Abstract
The topic of endocrine disruption in the aquatic environment is a clear example of a problem-driven research area. Field observations of endocrine abnormalities in wild life have prompted the growth of scientific attention and concern about the topic. Multiple studies have reported the presence of endocrine disrupting activities in various compartments of the aquatic environment, without, at the time, knowing the cause of the observations. The application of effect-directed analysis (EDA) has shown to be a valuable approach in investigating the nature of the compounds responsible for endocrine disrupting activities in environmental samples. Various research groups have applied EDA approaches and thereby successfully identified compounds responsible for endocrine disrupting effects. The research field of endocrine disruption is thus one of the research areas that has extensively experienced the benefits of EDA. This chapter describes the issue of endocrine disruption in the aquatic environment and discusses examples of the application of EDA for the identification of responsible compounds.
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Houtman, C.J., Legler, J., Thomas, K. (2011). Effect-Directed Analysis of Endocrine Disruptors in Aquatic Ecosystems. In: Brack, W. (eds) Effect-Directed Analysis of Complex Environmental Contamination. The Handbook of Environmental Chemistry(), vol 15. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-18384-3_10
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