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Membrane-Related Diseases

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Membrane Biophysics

Part of the book series: Biological and Medical Physics, Biomedical Engineering ((BIOMEDICAL))

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Abstract

Life starts with a single cell, but the cell is also where the origin of most pathological changes and disorders can be traced. Disease states can, in most cases, be linked to the abnormal functioning of specific organs. A living cell is the fundamental unit where most of these abnormalities happen and where they are initiated. That is why a cell is also the ultimate target for the action of most drugs. Cancer, Alzheimer’s disease, Parkinson’s disease, various infectious diseases, etc. originate in individual cellular compartments, including the membrane. This chapter will be dedicated to a better understanding of the membrane’s involvement in diseases, and disease treatment using drugs targeting cell membranes. Several examples will be used for illustration purposes. However, due to the book’s subject matter, we will concentrate on the scientific aspects of a few of the membrane-based diseases, leaving the medical issues aside. Below, we list several diseases that are either directly or indirectly related to membrane properties and their abnormalities.

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Authors and Affiliations

  1. Department of Biochemistry, College of Science, King Saud University, PO Box 2455, Riyadh, 11451, Saudi Arabia

    Mohammad Ashrafuzzaman

  2. Department of Physics,Cross Cancer Institute, University of Alberta, University Avenue 11560, Edmonton, AB, T6G 1Z2, Canada

    Jack Tuszynski

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  1. Mohammad Ashrafuzzaman
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  2. Jack Tuszynski
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Correspondence to Mohammad Ashrafuzzaman .

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© 2012 Springer-Verlag Berlin Heidelberg

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Ashrafuzzaman, M., Tuszynski, J. (2012). Membrane-Related Diseases. In: Membrane Biophysics. Biological and Medical Physics, Biomedical Engineering. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-16105-6_7

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  • DOI: https://doi.org/10.1007/978-3-642-16105-6_7

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