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Developmental Biology of Peripheral Lymphoid Organs pp 97–106Cite as

Structure and Development of Peyer’s Patches in Humans and Mice

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Abstract

Peyer’s patches are lymphoid organs situated on the anti-mesenteric side of the mid-intestine. Within the Peyer’s patches, immune responses to intestinal-derived antigens are initiated. In this chapter, we will discuss the structure and function of the Peyer’s patches. In addition, the development of Peyer’s patches during fetal life will be reviewed, with an emphasis on the reciprocal interaction between distinct hematopoietic cell subsets and their stromal environment in the Peyer’s patch anlage.

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Authors and Affiliations

  1. Department of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands

    Tom Cupedo

  2. Centre for Immunology and Infection, Department of Biology and Hull York Medical School, University of York, York, UK

    Mark C. Coles

  3. Immunobiology Unit, Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Lisboa, Portugal

    Henrique Veiga-Fernandes

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  1. Tom Cupedo
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  2. Mark C. Coles
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  3. Henrique Veiga-Fernandes
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Correspondence to Henrique Veiga-Fernandes .

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Editors and Affiliations

  1. , Department of Immunology and Biotechnolo, University of Pecs, Szigeti út 12, Pecs, 7624, Hungary

    Peter Balogh

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Cupedo, T., Coles, M.C., Veiga-Fernandes, H. (2011). Structure and Development of Peyer’s Patches in Humans and Mice. In: Balogh, P. (eds) Developmental Biology of Peripheral Lymphoid Organs. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-14429-5_9

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