Abstract
Both positron emission tomography (PET) and single photon emission computed tomography (SPECT) use radioactively labeled molecules that interact with a specific cellular target after injection. Images are formed by the detection of gamma rays, X-rays, or annihilation quanta (in the case of positron imaging). If single photon emitters are used, the direction of flight has to be determined by geometric collimation. In contrast, coincidence detection exploits the unique feature of positron annihilation which results in two high energy gamma rays simultaneously emitted back-to-back.
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Ziegler, S.I. (2011). PET and SPECT. In: Kiessling, F., Pichler, B. (eds) Small Animal Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-12945-2_17
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DOI: https://doi.org/10.1007/978-3-642-12945-2_17
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