Abstract
Dynamic MRI of the lung allows for real-time imaging of normal respiratory motion in 2D and of slow respiratory motion in 3D. 3D reconstructions and quantitative analysis confirmed that the diaphragm essentially has a piston-like function, but also showed that respiratory motion has a complex distribution over the diaphragm and the thoracic wall, and is further changed with body position. MRI-derived volumetry is well correlated to spirometric measurements and can be obtained for single lungs, allowing for regional assessment of lung function. With computational image registration and grid-tagging MRI, lung motion can be measured even at a subsegmental level. First experimental applications in chronic obstructive pulmonary disease, scoliosis, and radiation therapy proved the potential for the diagnosis and quantitative assessment of altered respiratory motion. Thus, it seems only a question of time until dynamic MRI enhances our understanding and diagnostics of respiratory mechanics in pulmonary disease.
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© 2009 Springer-Verlag Berlin Heidelberg
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Tetzlaff, R. (2009). Respiratory Mechanics and Pulmonary Motion. In: Kauczor, HU. (eds) MRI of the Lung. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-34619-7_5
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DOI: https://doi.org/10.1007/978-3-540-34619-7_5
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