Abstract
There may be many reasons why irregular functioning of the pacemaking mechanisms can occur. Both sympathetic and parasympathetic activity on the SAN and AVN have been linked to abnormal functionality and the genesis of atrial arrhythmias. One such mechanism by which they may do so is to cause a shift in the leading pacemaker site away from the centre of the SAN. AV-nodal rhythms occur either during periods of SAN dysfunction or AVN dysfunction, such as severe sinus bradycardia or AV-nodal re-entrant tachycardias. Hence, the ability to detect and characterise the presence of AV-nodal rhythms is of great importance.
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References
Fedorov VV, Ambrosi CM, Kostecki G, Hucker WJ, Glukhov AV, Wuskell JP et al (2011) Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts. Circ Arrhythm Electrophysiol 4(4):515–525
Coumel P (1994) Paroxysmal atrial fibrillation: a disorder of autonomic tone? Eur Heart J 15(Suppl A):9–16
Coumel P (1996) Autonomic influences in atrial tachyarrhythmias. J Cardiovasc Electrophysiol 7(10):999–1007
Fedorov VV, Chang R, Glukhov AV, Kostecki G, Janks D, Schuessler RB et al (2010) Complex interactions between the sinoatrial node and atrium during reentrant arrhythmias in the canine heart. Circulation 122(8):782–789
Colman MA, Aslanidi OV, Stott J, Holden AV, Zhang H (2011) Correlation between P-wave morphology and origin of atrial focal tachycardia–insights from realistic models of the human atria and torso. IEEE Trans Biomed Eng 58(10):2952–2955
Stenroos M, Haueisen J (2008) Boundary element computations in the forward and inverse problems of electrocardiography: comparison of collocation and Galerkin weightings. IEEE Trans Biomed Eng 55(9):2124–2133
Ohkubo K, Watanabe I, Yamada T, Okumura Y, Hashimoto K, Ashino S et al (2008) P wave morphology of an arrhythmogenic focus in patients with atrial fibrillation originating from a pulmonary vein or the superior vena cava. Circ J 72(10):1650–1657
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Colman, M.A. (2014). Pacemaking and Autonomic Regulation in the 3D Sinoatrial Node and Atria. In: Mechanisms of Atrial Arrhythmias. Springer Theses. Springer, Cham. https://doi.org/10.1007/978-3-319-01643-6_7
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DOI: https://doi.org/10.1007/978-3-319-01643-6_7
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