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Part of the book series: Clinical Trials ((CLINICAL))

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References

  1. Kellgren JH, Lawrence JS. Radiological assessment of osteo-arthrosis. Ann Rheum Dis 1957;16:494–502.

    Article  PubMed  CAS  Google Scholar 

  2. Cooper C. Osteoarthritis and related disorders: epidemiology. In Klippel JH, Dieppe PA, eds. Rheumatology. London: Harcourt Publishers Ltd; 2000:8.2.1–8.2.8.

    Google Scholar 

  3. Bellamy N, Kirwan J, Boers M, Brooks P, Strand V, Tugwell P, et al. Recommendations for a core set of outcome measures for future phase III clinical trials in knee, hip, and hand osteoarthritis. Consensus development at OMERACT III. J Rheumatol 1997;24:799–802.

    PubMed  CAS  Google Scholar 

  4. Bellamy N, Carr A, Dougados M, Shea B, Wells G. Towards a definition of “difference” in osteoarthritis. J Rheumatol 2001;28:427–430.

    PubMed  CAS  Google Scholar 

  5. Dougados M, Leclaire P, van der HD, Bloch DA, Bellamy N, Altman RD. Response criteria for clinical trials on osteoarthritis of the knee and hip: a report of the Osteoarthritis Research Society International Standing Committee for Clinical Trials response criteria initiative. Osteoarthritis Cartilage 2000;8:395–403.

    Article  PubMed  CAS  Google Scholar 

  6. The CONSORT Statement. 2004.

    Google Scholar 

  7. Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol 1988;15:1833–1840.

    PubMed  CAS  Google Scholar 

  8. Lequesne MG, Mery C, Samson M, Gerard P. Indexes of severity for osteoarthritis of the hip and knee. Validation–value in comparison with other assessment tests. Scand.J Rheumatol Suppl 1987;65:85–89.

    Article  CAS  Google Scholar 

  9. Hurst NP, Jobanputra P, Hunter M, Lambert M, Lochhead A, Brown H. Validity of Euroqol—a generic health status instrument—in patients with rheumatoid arthritis. Economic and Health Outcomes Research Group. Br J Rheumatol 1994;33:655–662.

    Article  PubMed  CAS  Google Scholar 

  10. Bellamy N, Campbell J, Haraoui B, Gerecz-Simon E, Buchbinder R, Hobby K, et al. Clinimetric properties of the AUSCAN Osteoarthritis Hand Index: an evaluation of reliability, validity and responsiveness. Osteoarthritis Cartilage 2002;10:863–869.

    Article  PubMed  CAS  Google Scholar 

  11. Poiraudeau S, Chevalier X, Conrozier T, Flippo RM, Liote F, Noel E, et al. Reliability, validity, and sensitivity to change of the Cochin hand functional disability scale in hand osteoarthritis. Osteoarthritis Cartilage 2001;9:570–577.

    Article  PubMed  CAS  Google Scholar 

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© 2008 Springer-Verlag London Limited

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Arden, N. (2008). Trial Design and Outcomes in Osteoarthritis. In: Reid, D.M., Miller, C.G. (eds) Clinical Trials in Rheumatoid Arthritis and Osteoarthritis. Clinical Trials. Springer, London. https://doi.org/10.1007/978-1-84628-742-8_6

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  • DOI: https://doi.org/10.1007/978-1-84628-742-8_6

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-85233-874-9

  • Online ISBN: 978-1-84628-742-8

  • eBook Packages: MedicineMedicine (R0)

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