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Extrinsic and Intrinsic Control of Germline Stem Cell Regulation in the Drosophila Ovary

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Book cover Regulatory Networks in Stem Cells

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

Germline stem cells (GSCs) in the Drosophila ovary represent one of the best studied adult stem cell types, while their regulatory microenvironment or niche is also one of the best defined ones. Due to the availability of powerful genetic tools and a large number of mutants, much progress has been made in understanding the molecular mechanisms underlying intrinsic and extrinsic controls of GSC regulation within the past decade. Since several excellent reviews have been written on these stem cells, this review primarily discusses progress within the last couple of years and important questions remaining to be answered.

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Authors and Affiliations

  1. Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110

    Nian Zhang & Ting Xie

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  1. Nian Zhang
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  2. Ting Xie
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Correspondence to Ting Xie .

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Editors and Affiliations

  1. Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Vinagolu K. Rajasekhar MSc, MPhil, PhD

  2. Invitrogen Corporation, Frederick, MD, USA

    Mohan C. Vemuri Ph.D.

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© 2009 Humana Press, a part of Springer Science+Business Media, LLC, a part of Springer Science+Business Media, LLC

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Zhang, N., Xie, T. (2009). Extrinsic and Intrinsic Control of Germline Stem Cell Regulation in the Drosophila Ovary. In: Rajasekhar, V.K., Vemuri, M.C. (eds) Regulatory Networks in Stem Cells. Stem Cell Biology and Regenerative Medicine. Humana Press. https://doi.org/10.1007/978-1-60327-227-8_14

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