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Pulmonary Arterial Hypertension in Pregnancy

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Book cover Pulmonary Problems in Pregnancy

Part of the book series: Respiratory Medicine ((RM))

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Abstract

Pulmonary arterial hypertension (PAH) is a disease of unknown etiology that affects young and middle-aged woman with greater frequency than the rest of the population (1). It is characterized by an elevation in pulmonary vascular resistance (PVR) and a decrease in cardiac output (CO) that results in right-sided heart failure and reduced exercise capacity. Without treatment, it usually progresses to right heart failure and death. Recently developed therapies have improved exercise capacity and prolonged survival, but a cure for this debilitating disease does not yet exist. Fortunately, the disease is extremely rare. Unfortunately it usually strikes without warning and occurs most often in women who are otherwise healthy.

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Acknowledgements

This paper was supported in part by NIH grant HL-088328-01 (JRK)

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  1. Division of Pulmonary/Critical Care and Sleep Medicine, Warren Alpert Medical School of Brown University, Rhode Island Hospital, 593 Eddy Street, Providence, RI 02903

    Brian Casserly MD (Teaching Fellow in Medicine (Pulmonary/Critical Care)

  2. Respiratory Care Unit, Division of Pulmonary Sleep and Critical Care Medicine, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, 593 Eddy Street, Providence, RI 02903, USA

    James R. Klinger MD (Associate Professor of Medicine, Medical Director)

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  1. Brian Casserly MD
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    © 2009 Humana Press, a part of Springer Science+Business Media, LLC

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    Casserly, B., Klinger, J.R. (2009). Pulmonary Arterial Hypertension in Pregnancy. In: Rosene-Montella, K., Bourjeily, G. (eds) Pulmonary Problems in Pregnancy. Respiratory Medicine. Humana Press. https://doi.org/10.1007/978-1-59745-445-2_19

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