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The Cardiac Lymphatic System

An Overview

  • Book
  • © 2013

Overview

Editors:
  1. Ganga Karunamuni

    1. School of Medicine, Case Western Reserve University, Cleveland, USA

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  • Provides in-depth coverage of the cardiac lymphatic vessels and the essential nature of their patterning and development
  • Useful to a broad audience interested in cardiovascular medicine and physiology
  • Gives readers vital information on the crucial role played by the cardiac lymphatic vessels in preserving normal heart function
  • Includes supplementary material: sn.pub/extras

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
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  2. Anatomy of the Cardiac Lymphatic System

    1. Front Matter

      Pages 1-1
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  3. Anatomy of the Cardiac Lymphatic System

    1. A General Outline of the Cardiac Lymphatic System

      • Marios Loukas, Sameer Shah, Shivayogi Bhusnurmath, Bharti Shivayogi Bhusnurmath, R. Shane Tubbs
      Pages 3-15

    2. Development and Patterning of the Cardiac Lymphatic Network

      • Jörg Wilting, Jörg Männer
      Pages 17-31

  4. The Cardiac Lymphatics and Heart Disease

    1. Front Matter

      Pages 33-33
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  5. The Cardiac Lymphatics and Heart Disease

    1. The Link Between Lymphatic Obstruction and Congenital Heart Disease

      • Manish Bansal
      Pages 35-44

    2. The Role of Lymphatics in Atherogenesis, Myocardial Infarction, Congestive Heart Failure, and Cardiac Transplantation

      • Shin Lin, Stanley G. Rockson
      Pages 45-62

    3. The Lymphatics in Normal and Pathological Heart Valves

      • Ivana Kholová, Galina Dragneva, Seppo Ylä-Herttuala
      Pages 63-71

    4. Therapeutic Applications Targeting the Cardiac Lymphatics in Heart Disease

      • Jae-Hyeong Park, Jin-Ok Jeong
      Pages 73-85

    5. Imaging the Lymphatic System in Heart Transplantation and Its Immunological Implications

      • Kathryn Brown, Lindsey A. Edwards, Wilson Wong
      Pages 87-103

  6. Cardiac Lymphatic Signaling

    1. Front Matter

      Pages 105-105
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  7. Cardiac Lymphatic Signaling

    1. Tie Receptor Signaling in Cardiac Lymphangiogenesis

      • Xianghu Qu, H. Scott Baldwin
      Pages 107-123

    2. VEGF Receptor Signaling in the Cardiac Lymphatics

      • Alexey Dashkevich, Karl B. Lemström, Antti I. Nykänen
      Pages 125-143

    3. Hypoxia and the Cardiac Lymphatic System

      • Todd R. Wuest, P. Charles Lin
      Pages 145-160

    4. The Potential of the Epicardium to Act as a Source of Lymphatic Cells

      • Linda Klotz, Paul Riley
      Pages 161-181

  8. Back Matter

    Pages 183-184
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Keywords

About this book

The heart is invested with a complex, intertwining network of blood and lymphatic vessels which, respectively, provide the cardiac tissue with oxygen and nutrients and eliminate excess fluid from the interstitium. The coronary blood vessels have been the focus of much investigation in the past few decades. On the other hand, the literature regarding the cardiac lymphatic vessels remains sparse, despite their important role in maintaining normal heart function. With this in mind, a better understanding of the cardiac lymphatic network and its ability to regulate fluid homeostasis within the heart could give us insight into developing therapies for the alleviation of several cardiac pathological conditions.

Editors and Affiliations

  • School of Medicine, Case Western Reserve University, Cleveland, USA

    Ganga Karunamuni

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