Abstract
Since Hippocrates described the anatomy of the blood and the lymphatic systems for the first time at BC400, these two vascular systems have been believed to be the only circulatory systems existing and operating in vertebrates. However, the oriental medicine that originates much prior to the Hippocrates era in the Western world has suggested the presence of a third neurovascular network that serves as a conduit for acupuncture meridian. While the controversies on the therapeutic efficacies of acupuncture have not been entirely resolved, a novel primo-vascular system has been discovered to be present on the surface of the internal organs and within the large vessels in the rat, rabbit, and other animals. The morphological and anatomical properties of this new primo-vascular system were originally characterized by a North Korean scientist, Dr. Bonghan Kim, and thus this primo-vascular system was named after him as Bonghan thread/duct. In this chapter, we will report our endeavor to study this primo-vessel present in the thoracic ducts of rodents.
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Soh KS (2009) Bonghan circulatory system as an extension of acupuncture meridians. J Acupunct Meridian Stud 2(2):93–106
Yoo JS, Kim MS, Ogay V, Soh KS (2008) In vivo visualization of bonghan ducts inside blood vessels of mice by using an Alcian blue staining method. Indian J Exp Biol 46(5):336–339
Sung B, Kim MS, Lee BC, Yoo JS, Lee SH, Kim YJ, Kim KW, Soh KS (2008) Measurement of flow speed in the channels of novel threadlike structures on the surfaces of mammalian organs. Naturwissenschaften 95(2):117–124
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, Chevalier B, Johnstone SE, Cole MF, Isono K, Koseki H, Fuchikami T, Abe K, Murray HL, Zucker JP, Yuan B, Bell GW, Herbolsheimer E, Hannett NM, Sun K, Odom DT, Otte AP, Volkert TL, Bartel DP, Melton DA, Gifford DK, Jaenisch R, Young RA (2006) Control of developmental regulators by Polycomb in human embryonic stem cells. Cell 125(2):301–313
Ogay V, Baik KY, Lee BC, Soh KS (2006) Characterization of DNA-containing granules flowing through the meridian-like system on the internal organs of rabbits. Acupunct Electrother Res 31(1–2):13–31
Lee BC, Yoo JS, Baik KY, Kim KW, Soh KS (2005) Novel threadlike structures (Bonghan ducts) inside lymphatic vessels of rabbits visualized with a Janus Green B staining method. Anat Rec B New Anat 286(1):1–7
Choi I, Chung HK, Ramu S, Lee HN, Kim KE, Lee S, Yoo J, Choi D, Lee YS, Aguilar B, Hong YK (2011) Visualization of lymphatic vessels by Prox1-promoter directed GFP reporter in a bacterial artificial chromosome-based transgenic mouse. Blood 117(1):362–365
Gong S, Zheng C, Doughty ML, Losos K, Didkovsky N, Schambra UB, Nowak NJ, Joyner A, Leblanc G, Hatten ME, Heintz N (2003) A gene expression atlas of the central nervous system based on bacterial artificial chromosomes. Nature 425(6961):917–925
Hong YK, Lange-Asschenfeldt B, Velasco P, Hirakawa S, Kunstfeld R, Brown LF, Bohlen P, Senger DR, Detmar M (2004) VEGF-A promotes tissue repair-associated lymphatic vessel formation via VEGFR-2 and the alpha1beta1 and alpha2beta1 integrins. FASEB J 18(10):1111–1113
Ogay V, Bae KH, Kim KW, Soh KS (2009) Comparison of the characteristic features of Bonghan ducts, blood and lymphatic capillaries. J Acupunct Meridian Stud 2(2):107–117
Lee BC, Kim KW, Soh KS (2009) Visualizing the network of Bonghan ducts in the omentum and peritoneum by using Trypan blue. J Acupunct Meridian Stud 2(1):66–70
Lee BC, Kim S, Soh KS (2008) Novel anatomic structures in the brain and spinal cord of rabbit that may belong to the Bonghan system of potential acupuncture meridians. J Acupunct Meridian Stud 1(1):29–35
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Choi, I., Chung, HK., Hong, YK. (2012). Detection of the Primo Vessels in the Rodent Thoracic Lymphatic Ducts. In: Soh, KS., Kang, K., Harrison, D. (eds) The Primo Vascular System. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-0601-3_17
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DOI: https://doi.org/10.1007/978-1-4614-0601-3_17
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