Abstract
In many laboratories, Single Photon Emission Computed Tomography imaging is the procedure of choice for nuclear cardiology procedures. Despite this, cardiac Positron Emission Tomography (PET) perfusion imaging has been recognized as superior to standard SPECT imaging due to higher image quality a greater efficiency [1]. However, it has been infrequently used due to limited availability of camera systems, radiopharmaceuticals and technical difficulties in cardiac acquisition and processing. Recently, the number of PET Camera systems has increased substantially and acquisition, processing and display of Cardiac PET studies has vastly improved. Thus, since its introduction in the early 1980s [2], the use of Cardiac (PET) perfusion imaging has greatly increased within the last 8 years. Its superior sensitivity and specificity over Single Photon Emission Computed Tomographic (SPECT) myocardial perfusion imaging [3], as well as the routine availability of Rubidium-82 (Rb-82), has made cardiac PET an important tool in the detection and risk stratification of coronary artery disease. This chapter will discuss some of the technical differences between PET and SPECT cameras, particularly as it relates to choice of technologies, and provide insights as to when PET might be preferable to SPECT for individual patients. A more detailed description of PET radiopharmaceuticals is provided in Part III (Chap. 13) and PET instrumentation in Part III (Chap. 14).
Keywords
- Positron Emission Tomography
- Single Photon Emission Compute Tomography
- Myocardial Perfusion Imaging
- Cardiac Sarcoidosis
- Cardiac Positron Emission Tomography
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsReferences
Bateman TM, Heller GV, McGhie AI, et al. Diagnostic accuracy of rest/stress ECG-gated Rb-82 myocardial perfusion PET: comparison with ECG-gated Tc-99 m sestamibi SPECT. J Nucl Cardiol. 2006;13(1):24–33.
Schelbert HR, Wisenberg G, Phelps ME, et al. Noninvasive assessment of coronary stenoses by myocardial imaging during pharmacologic coronary vasodilation. VI. Detection of coronary artery disease in human beings with intravenous N-13 ammonia and positron computed tomography. Am J Cardiol. 1982;49(5):1197–207.
Nandalur KR, Dwamena BA, Choudhri AF, Nandalur SR, Reddy P, Carlos RC. Diagnostic performance of positron emission tomography in the detection of coronary artery disease: a meta-analysis. Acad Radiol. 2008;15(4):444–51.
Cerqueira MD, Allman KC, Ficaro EP, et al. Recommendations for reducing radiation exposure in myocardial perfusion imaging. J Nucl Cardiol. 2010;17(4):709–18.
al Moudi M, Sun Z, Lenzo N. Diagnostic value of SPECT, PET and PET/CT in the diagnosis of coronary artery disease: a systematic review. Biomed Imaging Interv J. 2010;7(2):e9.
DeKemp RA, Yoshinaga K, Beanlands RS. Will 3-dimensional PET-CT enable the routine quantification of myocardial blood flow? J Nucl Cardiol. 2007;14(3):380–97.
Hendel RC, Berman DS, Di Carli MF, et al. ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 appropriate use criteria for cardiac radionuclide imaging: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. J Am Coll Cardiol. 2009;53(23):2201–29.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer-Verlag London
About this chapter
Cite this chapter
Lundbye, J. (2013). Cardiac Positron Emission Tomography. In: Heller, G., Hendel, R. (eds) Handbook of Nuclear Cardiology. Springer, London. https://doi.org/10.1007/978-1-4471-2945-5_2
Download citation
DOI: https://doi.org/10.1007/978-1-4471-2945-5_2
Published:
Publisher Name: Springer, London
Print ISBN: 978-1-4471-2944-8
Online ISBN: 978-1-4471-2945-5
eBook Packages: MedicineMedicine (R0)