Overview
Clinically focused overview of current and future therapies for progressive multiple sclerosis
Accessible guide for physicians who manage patients with progressive multiple sclerosis
Overview of hypotheses concerning the likely mechanisms of disease progression and how they relate to potential therapies
Extensive information on epidemiology, imaging pathology, treatment trials and biomarkers of relevance to progressive multiple sclerosis
Includes supplementary material: sn.pub/extras
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Table of contents (10 chapters)
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Front Matter
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Back Matter
Keywords
About this book
Progressive multiple sclerosis places a huge burden on individuals, carers and society and treatment options are currently limited. However, there have been significant recent advances in understanding progressive disease and this book draws the field together into a single, accessible, clinically focused text.
Progressive Multiple Sclerosis sets out the basic science, pathology, epidemiology and treatment possibilities in progressive multiple sclerosis. The biological processes underlying disease progression are elucidated as are specific pathophysiological mechanisms. The basic science of axonal degeneration and the clinical understanding of progressive multiple sclerosis are discussed in the context of emerging and future therapies for disease progression as are trials which might be conducted for progressive multiple sclerosis. An overview of biomarkers for the disease is included and existing symptomatic therapies for progressive multiple sclerosis are covered in detail. Each chapter addresses specific aspects of progressive multiple sclerosis providing an extensive review of the current literature and a discussion of the likely mechanisms of tissue injury relevant to the disease.
Progressive Multiple Sclerosis is ideal for both general neurologists and those with a specialist interest in multiple sclerosis. It will also be of interest to neurologists in training and other medical professionals treating this common disease.
Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
Reviews
From the reviews:
“Although there are plenty of books on multiple sclerosis, there are very few that solely cover progressive MS as this one does. … The book is written for neurologists and neurologists in training who grapple with the understanding and management of progressive multiple sclerosis. … This is an excellent overview of an often neglected topic in multiple sclerosis books.” (Joseph I. Sirven, Doody’s Review Service, November, 2012)Editors and Affiliations
About the editor
Dr Alastair Wilkins is Senior Lecturer in Neurology, University of Bristol, and Consultant Neurologist at Frenchay Hospital, Bristol, UK. He researches axonal injury in multiple sclerosis and related disorders.
Bibliographic Information
Book Title: Progressive Multiple Sclerosis
Editors: Alastair Wilkins
DOI: https://doi.org/10.1007/978-1-4471-2395-8
Publisher: Springer London
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer-Verlag London 2013
Softcover ISBN: 978-1-4471-6218-6Published: 20 September 2014
eBook ISBN: 978-1-4471-2395-8Published: 14 August 2012
Edition Number: 1
Number of Pages: XII, 252
Topics: Neurology, Internal Medicine