Abstract
This chapter provides a discussion on data management, databases, and data warehousing with particular reference to their utilization in cancer research. The section on data management describes the special requirements of data for research purposes. It discusses policies, ethics, and protocols involved in data collection, standardization, confidentiality, data entry and preparation, storage, quality assurance, and security. We have focused on the unique issues pertaining to data uniformity and consistency facilitating multi-institutional data sharing, data transfer, and collaboration. The section on Databases elaborates on the architecture and components of database systems. It also discusses various types of database systems with emphasis on the more commonly employed relational model of databases, database functions, and properties. In Data Warehousing the concept of data warehouses, along with warehouse architecture, technology, tools, and applications are discussed. A section on existing data resource systems has been detailed focusing on systems currently employed at the University of Pittsburgh to facilitate translational cancer research. There is a brief discussion on issues and approaches related to both databases and warehouses, which emphasizes their individual strengths and attributes.
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Acknowledgement
This work was supported by the following grants: Cooperative Prostate Cancer Tissue Resource – NCI U01 CA86735; Pennsylvania Cancer Alliance Bioinformatics Consortium – PA DOH – ME 01-740; Cancer Center Support Grant – NCI – P30 CA47904; Shared Pathology Informatics Network – NCI – U01 CA091338; caBIG – NCI Contracts – 94125DBS47 and 28XS210; NMVB – CDC NIOSH – 5 – U19 OH009077-02 and U24 OH009077-03; Clinical and Translational Science Award – NCRR – (UL1 RR024153-03).
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Amin, W., Kang, H.P., Becich, M.J. (2010). Data Management, Databases, and Warehousing. In: Ochs, M., Casagrande, J., Davuluri, R. (eds) Biomedical Informatics for Cancer Research. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-5714-6_3
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