Abstract
Diseases and/or disorders of the pulmonary system may affect brain behavior relationships due to impaired oxygen delivery (i.e., anoxia, hypoxia). Neurons are dependent on oxygen and without oxygen cellular function is disrupted and damage to cell structure leading to neuronal death may follow. A variety of respiratory disorders such as cardiac or respiratory arrest, carbon monoxide poisoning, obstructive sleep apnea, chronic obstructive pulmonary disease, and acute respiratory distress syndrome result in anoxia or hypoxia which can result in anoxic brain injury. The neuronal injury is manifest structurally by lesions and neuronal atrophy and functionally as neurocognitive and neuropsychiatric impairments.
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Hopkins, R.O. (2010). Respiratory Disorders: Effects on Neurocognitive and Brain Function. In: Armstrong, C., Morrow, L. (eds) Handbook of Medical Neuropsychology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1364-7_8
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