An internal control region of genes (5S ribosomal RNA and tRNA) transcribed by DNA-dependent RNA polymerase III; the consensus is 5′-TGGCNNAGTGG-3′. The tRNA genes also have an essential intermediate segment of about a dozen bases that has no consensus, yet its length is necessary for function. Nearby there is also another regulatory consensus, the B box 5′-GGTTCGAANNC-3′. The matrix attachment region (MAR) is also an A box (with a consensus of AATTAAA/CAAA). MAR; Borovjagin AV, Gerbi SA 2001 Mol Cell Biol 21:6210.
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© 2008 Springer Science+Business Media
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(2008). A Box. In: Encyclopedia of Genetics, Genomics, Proteomics and Informatics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6754-9_8
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DOI: https://doi.org/10.1007/978-1-4020-6754-9_8
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