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Breast MRI

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Abstract

Breast MRI has become one of the most useful breast imaging modalities. It is the most sensitive modality for detection of invasive ductal carcinoma. It will likely play an increasing role in screening women at high risk for developing breast cancer. Although there remains significant variability in specificity of MRI interpretation, as practice patterns become more established and standardized, variability should decrease.

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References

  1. El Yousef SJ, Duchesneau RH, Alfidi RJ, Haaga JR, Bryan PJ, LiPuma JP. Magnetic resonance imaging of the breast. Radiology. 1984;150:761.

    CAS  PubMed  Google Scholar 

  2. Zakaria S, Brandt KR, Degnim AC, Thomsen KM. Patients’ perceptions of breast MRI: a single-center study. Am J Roentgenol. Apr 2009;192:1149–1154.

    Article  Google Scholar 

  3. Bassett LW, Dhaliwal SG, Eredat J, et al. National trends and practices in breast MRI. AJR. 2008;191:332–339.

    Article  PubMed  Google Scholar 

  4. Erguvan-Dogan B, Whitman GJ, Kushwaha AC, Phelps MJ, Dempsey PJ. BI-RADS-MRI: A primer. Am J Roentgenol. Aug 2006;187:W152–W160.

    Article  Google Scholar 

  5. Orel SG, Schnall MD. MR imaging of the breast for the detection, diagnosis, and staging of breast cancer. Radiology. 2001;220:13.

    CAS  PubMed  Google Scholar 

  6. Sardanelli F, Giuseppetti GM, Panizza P, et al. Sensitivity of MRI versus mammography for detecting foci of multifocal, multicentric breast cancer in fatty and dense breasts using the whole-breast pathologic examination as a gold standard. Am J Roentgenol. Oct 2004;183:1149–1157.

    Google Scholar 

  7. Schell AM, Rosenkranz K, Lewis PJ. Role of breast MRI in the preoperative evaluation of patients with newly diagnosed breast cancer. Am J Roentgenol. May 2009;192:1438–1444.

    Article  Google Scholar 

  8. Lee JM, Orel SG, Czerniecki BJ, Solin LJ, Schnall MD. MRI before reexcision surgery in patients with breast cancer. Am J Roentgenol. Feb 2004;182:473–480.

    Google Scholar 

  9. Katipamula R, Hoskin TL, Boughey JC, et al. Trends in mastectomy rates at the Mayo Clinic Rochester: Effect of surgical year and preoperative MRI. J Clin Oncol (Meeting Abstracts). 2008;26:509.

    Google Scholar 

  10. Pediconi F, Catalano C, Roselli A, et al. Contrast-enhanced MR mammography for evaluation of the contralateral breast in patients with diagnosed unilateral breast cancer or high-risk lesions. Radiology. 2007;243:670–680.

    Article  PubMed  Google Scholar 

  11. Slanetz PJ, Edmister WB, Yeh ED, Talele AC, Kopans DB. Occult contralateral breast carcinoma incidentally detected by breast magnetic resonance imaging. Breast J. 2002;8:145–148.

    Article  PubMed  Google Scholar 

  12. Liberman L, Morris EA, Kim CM, et al. MR imaging findings in the contralateral breast of women with recently diagnosed breast cancer. AJR Am J Roentgenol. 2003;180:333–341.

    PubMed  Google Scholar 

  13. Lehman CD, Gatsonis C, Kuhl CK, et al. MRI evaluation of the contralateral breast in women with recently diagnosed breast cancer. N Engl J Med. 2007;356:1295–1303.

    Article  CAS  PubMed  Google Scholar 

  14. Morrow M. Magnetic resonance imaging in the preoperative evaluation of breast cancer: primum non nocere. J Am Coll Surg. 2004;198:240–241.

    Article  PubMed  Google Scholar 

  15. Solin LJ, Orel SG, Hwang W-T, Harris EE, Schnall MD. Relationship of breast magnetic resonance imaging to outcome after breast-conservation treatment with radiation for women with early-stage invasive breast carcinoma or ductal carcinoma in situ. J Clin Oncol. 2008;26:386–391.

    Article  PubMed  Google Scholar 

  16. Fischer U, Zachariae O, Baum F, von Heyden D, Funke M, Liersch T. The influence of preoperative MRI of the breasts on recurrence rate in patients with breast cancer. Eur Radiol. 2004;14:1725–1731.

    PubMed  Google Scholar 

  17. Morris EA, Schwartz LH, Dershaw DD, Van Zee KJ, Abramson AF, Liberman L. MR imaging of the breast in patients with occult primary breast carcinoma. Radiology. 1997;205:437–440.

    CAS  PubMed  Google Scholar 

  18. Orel SG, Weinstein SP, Schnall MD, et al. Breast MR imaging in patients with axillary node metastases and unknown primary malignancy. Radiology. 1999;212:543–549.

    CAS  PubMed  Google Scholar 

  19. Vinnicombe SJ, MacVicar AD, Guy RL, et al. Primary breast cancer: mammographic changes after neoadjuvant chemotherapy, with pathologic correlation. Radiology. 1996;198:333.

    CAS  PubMed  Google Scholar 

  20. Rosen EL, Blackwell KL, Baker JA, et al. Accuracy of MRI in the detection of residual breast cancer after neoadjuvant chemotherapy. Am J Roentgenol. Nov 2003;181:1275–1282.

    Google Scholar 

  21. Partridge SC, Gibbs JE, Lu Y, Esserman LJ, Sudilovsky D, Hylton NM. Accuracy of MR imaging for revealing residual breast cancer in patients who have undergone neoadjuvant chemotherapy. AJR. 2002;179:1193–1199.

    PubMed  Google Scholar 

  22. Yeh E, Slanetz P, Kopans DB, et al. Prospective comparison of mammography, sonography, and MRI in patients undergoing neoadjuvant chemotherapy for palpable breast cancer. Am J Roentgenol. Mar 2005;184:868–877.

    Google Scholar 

  23. Balu-Maestro C, Chapellier C, Bleuse A, Chanalet I, Chauvel C, Largillier R. Imaging in evaluation of response to neoadjuvant breast cancer treatment benefits of MRI. Breast Can Res Treatm. 2002;72:145–152.

    Article  CAS  Google Scholar 

  24. Delille JP, Slanetz PJ, Yeh ED, Halpern EF, Kopans DB, Garrido L. Invasive ductal breast carcinoma response to neoadjuvant chemotherapy: noninvasive monitoring with functional MR imaging – pilot study. Radiology. 2003;228:63–69.

    Article  PubMed  Google Scholar 

  25. Partridge SC, Gibbs JE, Lu Y, et al. MRI measurements of breast tumor volume predict response to neoadjuvant chemotherapy and recurrence-free survival. AJR. 2005;184:1774–1781.

    PubMed  Google Scholar 

  26. Hattangadi J, Park C, Rembert J, et al. Breast stromal enhancement on MRI is associated with response to neoadjuvant chemotherapy. Am J Roentgenol. Jun 2008;190:1630–1636.

    Article  Google Scholar 

  27. Loo CE, Teertstra HJ, Rodenhuis S, et al. Dynamic contrast-enhanced MRI for prediction of breast cancer response to neoadjuvant chemotherapy: Initial results. Am J Roentgenol. Nov 2008;191:1331–1338.

    Article  Google Scholar 

  28. El Khoury C, Servois V, Thibault F, et al. MR quantification of the washout changes in breast tumors under preoperative chemotherapy: Feasibility and preliminary results. AJR. 2005;184:1499–1504.

    PubMed  Google Scholar 

  29. Kuhl KC. Current status of breast mr imaging Part 2. Clinical applications. Radiology. 2007;244:672–691.

    Article  PubMed  Google Scholar 

  30. Leung JWT, Sickles EA. Developing asymmetry identified on mammography: Correlation with imaging outcome and pathologic findings. Am J Roentgenol. Mar 2007;188:667–675.

    Article  Google Scholar 

  31. Sickles EA. Periodic mammographic follow-up of probably benign lesions: Results in 3,184 consecutive cases. Radiology. 1991;179:463.

    CAS  PubMed  Google Scholar 

  32. Bazzocchi M, Zuiani C, Panizza P, et al. Contrast-enhanced breast mri in patients with suspicious microcalcifications on mammography: Results of a multicenter trial. Am J Roentgenol. Jun 2006;186:1723–1732.

    Article  Google Scholar 

  33. Morris EA, Liberman L, Ballon DJ, et al. MRI of occult breast carcinoma in a high-risk population. AJR. 2003;181:619–626.

    PubMed  Google Scholar 

  34. Kriege M, Brekelmans CT, Boetes C, et al. Efficacy of MRI and mammography for breast cancer screening in women with a familial or genetic predisposition. N Engl J Med. 2004;351:427–437.

    Article  CAS  PubMed  Google Scholar 

  35. Warner E, Plewes DB, Hill KA, et al. Surveillance of BRCA1 and BRCA2 mutation carriers with magnetic resonance imaging, ultrasound, mammography and clinical breast examination. J Am Med Assoc. 2004;292:1317–1325.

    Article  CAS  Google Scholar 

  36. Lehman CD, Blume JD, Weatherall P, et al. Screening women at high risk for breast cancer with mammography and magnetic resonance imaging. Cancer. 2005;103:1898–1905.

    Article  PubMed  Google Scholar 

  37. Kuhl CK, Schrading S, Leutner CC, et al. Mammography, breast ultrasound and magnetic resonance imaging for surveillance of women at high familial risk for breast cancer. J Clin Oncol. 2005;23:8469–8476.

    Article  PubMed  Google Scholar 

  38. Leach MO, Boggis CR, Dixon AK, et al. Screening with magnetic resonance imaging and mammography of a UK population at high familial risk for breast cancer: A prospective multicentre cohort study (MARIBS). Lancet. 2005;365:1769–1778.

    Article  CAS  PubMed  Google Scholar 

  39. Saslow D, Boetes C, Burke W, et al. American Cancer Society guidelines for breast screening with MRI as an adjunct to mammography. CA Cancer J Clin. 2007;57:75–89.

    Article  PubMed  Google Scholar 

  40. Kuhl CK, Träber F, Gieseke J, et al. (3.0-T) MR imaging in clinical practice Part II. Technical considerations and clinical applications. Radiology. 2008;247:16–35.

    Article  PubMed  Google Scholar 

  41. Kuhl CK, Jost P, Morakkabati N, Zivanovic O, Schild HH, Gieseke J. Contrast-enhanced MR imaging of the breast at 3.0 and 1.5 T in the same patients: Initial experience. Radiology. 2006;239:666–676.

    Article  PubMed  Google Scholar 

  42. Ghai S, Muradali D, Bukhanov K, Kulkarni S. Nonenhancing breast malignancies on MRI: Sonographic and pathologic correlation. Am J Roentgenol. Aug 2005;185:481–487.

    Google Scholar 

  43. Erguvan-Dogan B, Whitman GJ, Kushwaha AC, Phelps MJ, Dempsey PJ. BI-RADS-MRI: A primer. Am J Roentgenol. Aug 2006;187:W152–W160.

    Article  Google Scholar 

  44. Ikeda DM, Hylton MD, Karen Kinkel NM, et al. Development, standardization, and testing of a lexicon for reporting contrast-enhanced breast magnetic resonance imaging studies. JMRI. 2001;13(6):889–895.

    Article  CAS  PubMed  Google Scholar 

  45. Heywang-Kobrunner SH, Heinig A, Pickuth D, et al. Interventional MRI of the breast: lesion localization and biopsy. Eur Radiol. 2000;10:36–45.

    Article  CAS  PubMed  Google Scholar 

  46. Orel SG, Rosen M, Mies C, Schnall MD. MR imaging-guided 9-gauge vacuum-assisted core-needle breast biopsy: Initial experience. Radiology. Dec 2005;238(1):54–61.

    Article  PubMed  Google Scholar 

  47. Liberman L, Morris EA, Dershaw DD, Thornton CM, Van Zee KJ, Tan LK. Fast MRI-guided vacuum-assisted breast biopsy: Initial experience. Am J Roentgenol. Nov 2003;181(5):1283–1293.

    Google Scholar 

  48. Perlet C, Heywang-Kobrunner SH, Heinig A, et al. Magnetic resonance–guided, vacuum-assisted breast biopsy: Results from a European multicenter study of 538 lesions. Cancer. 2006;106:982–990.

    Article  PubMed  Google Scholar 

  49. Morris EA, Liberman L, Dershaw DD. Preoperative MR imaging-guided needle localization of breast lesions. AJR Am J Roentgenol. 2002;178:1211–1220.

    PubMed  Google Scholar 

  50. Erguvan-Dogan B, Whitman GJ, et al. Specimen radiography in confirmation of MRI-guided needle localization and surgical excision of breast lesions. Am J Roentgenol. Aug 2006;187:339–344.

    Article  Google Scholar 

  51. 51. LaTrenta LR, Menell JH, Morris EA, Abramson AF, Dershaw DD, Liberman L. Breast lesions detected with MR imaging: utility and histopathologic importance of identification with US. Radiology. 2003;227:856–861.

    Article  PubMed  Google Scholar 

  52. DeMartini WB, Eby PR, Peacock S, Lehman CD. Utility of targeted sonography for breast lesions that were suspicious on MRI. AJR. 2009;192:1128–1134.

    Article  PubMed  Google Scholar 

  53. Roebuck JR, Cecil KM, Schnall MD, Lenkinski RE. Human breast lesions: characterization with proton MR spectroscopy. Radiology. 1998;209:269.

    CAS  PubMed  Google Scholar 

  54. Bartella L, Morris EA, Dershaw DD, et al. Proton MR spectroscopy with choline peak as malignancy marker improves positive predictive value for breast cancer diagnosis: Preliminary study. Radiology. 2006;239:686–692.

    Article  PubMed  Google Scholar 

  55. Bartella L, Thakur SB, Morris EA, et al. Enhancing nonmass lesions in the breast: evaluation with proton (1H) MR spectroscopy. Radiology. 2007;245:80–87.

    Article  PubMed  Google Scholar 

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Correspondence to Barbara C. Cavanaugh .

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Cavanaugh, B.C., McNally, S. (2010). Breast MRI. In: Sauter, E., Daly, M. (eds) Breast Cancer Risk Reduction and Early Detection. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-87583-5_8

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  • DOI: https://doi.org/10.1007/978-0-387-87583-5_8

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