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Postsynaptic Transport Packets

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Book cover Molecular Mechanisms of Synaptogenesis

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Summary

To understand the molecular methods by which synapse formation occurs, it is critical to know the mechanisms by which all the synaptic components can possibly arrive at a newly forming synapse. Methods of trafficking can range from diffusion through the cytoplasm or in the plasma membrane to exo/endocytic cycling between bouts of transport along microtubules. In the case of the postsynaptic density (PSD) of glutamatergic synapses, it appears that many of the necessary proteins arrive separately and by different means. Here we examine the modes of transport and recruitment of a number of postsynaptic components to newly forming, glutamatergic synapses.

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Authors and Affiliations

  1. Institute of Neuroscience, University of Oregon, Eugene, OR, 97403, USA

    Philip E. Washbourne

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  1. Philip E. Washbourne
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  1. University Medical Center Hamburg-Eppendorf, 52 Martinistrasse, Hamburg, 20246, Germany

    Alexander Dityatev

  2. University of British Columbia, 2255 Wesbrook Mall, Vancouver, British Columbia, Canada, V6T 2A1

    Alaa El-Husseini

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Washbourne, P.E. (2006). Postsynaptic Transport Packets. In: Dityatev, A., El-Husseini, A. (eds) Molecular Mechanisms of Synaptogenesis. Springer, Boston, MA . https://doi.org/10.1007/978-0-387-32562-0_15

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