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Glutamate synthase (NADH)

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Springer Handbook of Enzymes

Part of the book series: Springer Handbook of Enzymes ((HDBKENZYMES,volume 22))

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1 Nomenclature

EC number

1.4.1.14

Systematic name

-lglutamate:NADP+oxidoreductase (transminating)

Recommended name

glutamate synthase (NADPH)

Synonyms

-lglutamate synthase (NADH)

-lglutamate synthetase

NADPH-GOGAT

NADPH-GltS

NADPH-dependent glutamate synthase

NADPH-glutamate synthase

NADPH:GOGAT

glutamate (reduced nicotinamide adenine dinucleotide) synthase

glutamate synthase

glutamate synthase (NADH)

glutamate synthase (NADH-dependent)

glutamate synthase

synthase, glutamate (reduced nicotinamide adenine dinucleotide

CAS registry number

65589-88-0

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References

  1. Boland, M.J.; Benny, A.G.: Enzymes of nitrogen metabolism in legume nodules. Purification and properties of NADH-dependent glutamate synthase from lupin nodules. Eur. J. Biochem., 79, 355–362 (1977)

    Article  PubMed  CAS  Google Scholar 

  2. Hayakawa, T.; Yamaya, T.; Kamachi, K.; Ojima, K.: Purification, characterization, and immunological properties of NADH-dependent glutamate synthase from rice cell cultures. Plant Physiol., 98, 1317–1322 (1992)

    PubMed  CAS  Google Scholar 

  3. Anderson, M.P.; Vance, C.P.; Heichel, G.H.; Miller, S.S.: Purification and characterization of NADH-glutamate synthase from alfalfa root nodules. Plant Physiol., 90, 351–358 (1989)

    PubMed  CAS  Google Scholar 

  4. Chen, F.L.; Cullimore, J.V.: Two isoenzymes of NADH-dependent glutamate synthase in root nodules of Phaseolus vulgaris L.. Purification, properties and activity changes during nodule development. Plant Physiol., 88, 1411–1417 (1988)

    PubMed  CAS  Google Scholar 

  5. Singhal, R.K.; Krishnan, I.S.; Dua, R.D.: Stabilization, purification, and characterization of glutamate synthase from Clostridium pasteurianum. Biochemistry, 28, 7928–7935 (1989)

    Article  PubMed  CAS  Google Scholar 

  6. Masters, D.S.; Meister, A.: Inhibition by homocysteine sulfonamide of glutamate synthase purified from Saccharomyces cerevisiae. J. Biol. Chem., 257, 8711–8715 (1982)

    PubMed  CAS  Google Scholar 

  7. Romero, D.; Davila, G.: Genetic and biochemical identification of the glutamate synthase structural gene in Neurospora crassa. J. Bacteriol., 167, 1043–1047 (1986)

    PubMed  CAS  Google Scholar 

  8. Wang, R.; Nicholas, D.J.D.: Some properties of glutamine synthetase and glutamate synthase from Derxia gummosa. Phytochemistry, 24, 1133–1139 (1985)

    Article  CAS  Google Scholar 

  9. Cullimore, J.V.; Sims, A.P.: Occurrence of two forms of glutamate synthase in Chlamydomonas reinhardii. Phytochemistry, 20, 597–600 (1981)

    Article  CAS  Google Scholar 

  10. Khanna, S.; Nicholas, D.J.D.: Some properties of glutamine synthetase and glutamate synthase from Chlorobium vibrioforme f. thiosulfatophilum. Arch. Microbiol., 134, 98–103 (1983)

    Article  CAS  Google Scholar 

  11. Boland, M.J.; Court, C.B.: Glutamate synthase (NADH) from lupin nodules. Specificity of the 2-oxoglutarate site. Biochim. Biophys. Acta, 657, 539–542 (1981)

    PubMed  CAS  Google Scholar 

  12. Hummelt, G.; Mora, J.: NADH-dependent glutamate synthase and nitrogen metabolism in Neurospora crassa. Biochem. Biophys. Res. Commun., 92, 127–133 (1980)

    Article  PubMed  CAS  Google Scholar 

  13. Miyatake, K.; Kitaoka, S.: NADH-dependent glutamate synthase in Euglena gracilis Z. Agric. Biol. Chem., 45, 1727–1729 (1981)

    CAS  Google Scholar 

  14. Boland, M.J.: NADH-dependent glutamate synthase from lupin nodules. Reactions with oxidised and reduced 3-acetylpyridine-adenine dinucleotide. Eur. J. Biochem., 115, 485–489 (1981)

    Article  PubMed  CAS  Google Scholar 

  15. Marquez, A.J.; Galvan, F.; Vega, J.M.: Purification and characterization of the NADH-glutamate synthase from Chlamydomonas reinhardii. Plant Sci. Lett., 34, 305–314 (1984)

    Article  CAS  Google Scholar 

  16. Roon, R.J.; Even, H.I.; Larimore, R: Glutamate synthase: Properties of the reduced nicotinamide adenine dinucleotide-dependent enzyme from Saccharomyces cerevisiae. J. Bacteriol., 118, 89–95 (1974)

    PubMed  CAS  Google Scholar 

  17. Boland, M.J.: Kinetic mechanism of NADH-dependent glutamate synthase from lupin nodules. Eur. J. Biochem., 99, 531–539 (1979)

    Article  PubMed  CAS  Google Scholar 

  18. Meister, A.: Glutamate synthase from Escherichia coli, Klebsiella aerogenes, and Saccharomyces cerevisiae. Methods Enzymol., 113, 327–337 (1985)

    Article  PubMed  CAS  Google Scholar 

  19. Cordovilla, M.P.; Perez, J.; Ligero, F.; Lluch, C.; Valpuesta, V.: Partial purification and characterization of NADH-glutamate synthase from faba bean (Vicia faba) root nodules. Plant Sci., 150, 121–128 (2000)

    Article  Google Scholar 

  20. Ishiyama, K.; Hayakawa, T.; Yamaya, T.: Expression of NADH-dependent glutamate synthase protein in the epidermis and exodermis of rice roots in response to the supply of ammonium ions. Planta, 204, 288–294 (1998)

    Article  PubMed  CAS  Google Scholar 

  21. Hayakawa, T.; Hopkins, L.; Peat, L.J.; Yamaya, T.; Tobin, A.K.: Quantitative intercellular localization of NADH-dependent glutamate synthase protein in different types of root cells in rice plants. Plant Physiol., 119, 409–416 (1999)

    Article  PubMed  CAS  Google Scholar 

  22. Obara, M.; Kajiura, M.; Fukuta, Y.; Yano, M.; Hayashi, M.; Yamaya, T.; Sato, T.: Mapping of QTLs associated with cytosolic glutamine synthetase and NADH-glutamate synthase in rice (Oriza sativa L.). J. Exp. Bot., 52, 1209–1217 (2001)

    Article  PubMed  CAS  Google Scholar 

  23. Doverskog, M.; Jacobsson, U.; Chapman, B.E.; Kuchel, P.W.; Häggström, L.: Determination of NADH-dependent glutamate synthase (GOGAT) in Spodoptera frugiperda (Sf9) insect cells by a selective 1H/15N NMR in vitro assay. J. Biotechnol., 79, 87–97 (2000)

    Article  PubMed  CAS  Google Scholar 

  24. Vanoni, M.A.; Curti, B.: Glutamate synthase: A complex iron-sulfur flavoprotein. Cell. Mol. Life Sci., 55, 617–638 (1999)

    Article  PubMed  CAS  Google Scholar 

  25. Vance, C.P.; Miller, S.S.; Gregerson, D.L.; Samac, D.A.; Robinson, D.L.; Gantt, J.S.: Alfalfa NADH-dependent glutamate synthase: Structure of the gene and importance in symbiotic N2 fixation. Plant J., 8, 345–358 (1995)

    Article  PubMed  CAS  Google Scholar 

  26. Chichkova, S.; Arellano, J.; Vance, C.P.; Hernandez, G.: Transgenic tobacco plants that overexpress alfalfa NADH-glutamate synthase have higher carbon and nitrogen content. J. Exp. Bot., 52, 2079–2087 (2001)

    PubMed  CAS  Google Scholar 

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Editors and Affiliations

  1. Institute for Biochemistry, University to Cologne, Zülpicher Strasse 47, 50674, Cologne, Germany

    Dietmar Schomburg  & Ida Schomburg  & 

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© 2005 Springer-Verlag Berlin Heidelberg

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(2005). Glutamate synthase (NADH). In: Schomburg, D., Schomburg, I. (eds) Springer Handbook of Enzymes. Springer Handbook of Enzymes, vol 22. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-37646-1_14

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