Skip to main content
SpringerLink
Log in
Book cover

Contact Dermatitis pp 97–104Cite as

Mechanisms of Phototoxic and Photoallergic Reactions

  • Chapter

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   229.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Ferguson J (1999) Drug and chemical photosensitivity. In: Hawk JLM (ed) Photodermatology. Arnold, London pp 155–169

    Google Scholar 

  2. Krutmann J, Hönigsmann H, Elmets CA, Bergstresser PR (eds) (2000) Dermatological phototherapy and photodiagnostic methods. Springer, Berlin Heidelberg New York

    Google Scholar 

  3. Epstein JH (1989) Photomedicine. In: Smith KC (ed) The science of photobiology, 2nd edn. Plenum, New York, pp 155–192

    Google Scholar 

  4. Epstein JH (1983) Phototoxicity and photoallergy in man. J Am Acad Dermatol 8:141–147

    Article  PubMed  CAS  Google Scholar 

  5. Hölzle E, Plewig G, Lehmann P (1987) Photodermatoses — diagnostic procedures and their interpretation. Photodermatology 4:109–114

    PubMed  Google Scholar 

  6. Gould JW, Mercurio MG, Elmets CA (1995) Cutaneous photosensitivity diseases induced by exogenous agents. J Am Acad Dermatol 33:551–573

    Article  PubMed  CAS  Google Scholar 

  7. Fritsch C, Goerz G, Ruzicka T (1998) Photodynamic therapy in dermatology. Arch Dermatol 134:207–214

    Article  PubMed  CAS  Google Scholar 

  8. Lim HW (1989) Mechanisms of phototoxicity in porphyria cutanea tarda and erythropoietic protoporphyria. Immunol Ser 46:671–685

    PubMed  CAS  Google Scholar 

  9. Strauss GH, Bridges BA, Greaves M, Vella-Briffa D, Hall-Smith P, Price M (1980) Methoxypsoralen photochemotherapy. Lancet 122:1134–1135

    Article  Google Scholar 

  10. Gonzalez E, Gonzalez S (1996) Drug photosensitivity, idiopathic photodermatoses, and sunscreens. J Am Acad Dermatol 35:871–885

    Article  PubMed  CAS  Google Scholar 

  11. Ljunggren B, Bjellerup M (1986) Systemic drug photosensitivity. Photodermatology 3:26–35

    PubMed  CAS  Google Scholar 

  12. Quintero B, Miranda MA (2000) Mechanisms of photosensitization induced by drugs: a general survey. Ars Pharmadeutica 1:27–46

    Google Scholar 

  13. Quedraogo G, Morliere P, Santus R, Miranda, Castell JV (2000) Damage to mitochondria of cultured human skin fibroblasts photosensitized by fluoroquinolones. J Photochem Photobiol 58:20–25

    Article  Google Scholar 

  14. Kochevar KE (1991) Phototoxicity mechanisms: chlorpromazine photosensitized damage to DNA and cell membranes. J Invest Dermatol 77:59–64

    Article  Google Scholar 

  15. Terencio MC, Guillen I, Gomez-Lechon MJ, Miranda MA, Castell JV (1998) Release of inflammatory mediators (PGE2, IL-6) by fenofibric acid-photosensitized human keratinocytes and fibroblasts. Photochem Photobiol 68:331–336

    Article  PubMed  CAS  Google Scholar 

  16. Diffey BL, Farr PM, Adams SJ (1988) The action spectrum in quinine photosensitivity. Br J Dermatol 118:679–685

    PubMed  CAS  Google Scholar 

  17. Diffey BL, Farr PM (1988) The action spectrum in drug induced photosensitivity. Photochem Photobiol 47:49–53

    PubMed  CAS  Google Scholar 

  18. Dall’Acqua F, Vedaldi D, Bordin F, Rodighiero G (1979) New studies on the interaction between 8-methoxypsoralen and DNA in vitro. J Invest Dermatol 73:191–197

    Article  PubMed  CAS  Google Scholar 

  19. Laskin JD, Lee E, Laskin DL, Gallo MA (1986). Psoralens potentiate ultraviolet light-induced inhibition of epidermal growth factor binding. Proc Natl Acad Sci USA 83:8211–8215

    Article  PubMed  CAS  Google Scholar 

  20. Zarebska Z (1994) Cell membrane, a target for PUVA therapy. J Photochem Photobiol B 23:101–109

    Article  PubMed  CAS  Google Scholar 

  21. Anthony FA, Laboda HM, Costlow ME (1997) Psoralen-fatty acid adducts activate melanocyte protein kinase C: a proposed mechanism for melanogenesis induced by 8-methoxypsoralen and ultraviolet A light. Photodermatol Photoimmunol Photomed 13:9–16

    PubMed  CAS  Google Scholar 

  22. Coven TR., Walters IB, Cardinale I, Krueger JG (1999) PUVA-induced lymphocyte apoptosis: mechanism of action in psoriasis. Photodermatol Photoimmunol Photomed 15:22–27

    PubMed  CAS  Google Scholar 

  23. Pathak MA, Daniels F, Fitzpatrick TB (1962) The presently known distribution of furocomarins (psoralens) in plants. J Invest Dermatol 32:225–239

    Article  Google Scholar 

  24. Kavli G, Volden G (1984) Phytophotodermatitis. Photodermatology 1:65–75

    PubMed  CAS  Google Scholar 

  25. Dawe RS, Ibbotson SH, Sanderson JB, Thomson EM, Ferguson J (2003) A randomized controlled trial (volunteer study) of sitafloxacin, enoxacin, levofloxacin and sparfloxacin phototoxicity. Br J Dermatol 149:1232–1241

    Article  PubMed  CAS  Google Scholar 

  26. Kawada A, Hatanaka K, Gomi H, Matsuo I (1999) In vitro phototoxicity of new quinolones: production of active oxygen species and photosensitized lipid peroxidation. Photodermatol Photoimmunol Photomed 15:226–230

    Article  PubMed  CAS  Google Scholar 

  27. Neumann NJ, Holzle E, Lehmann P, Rosenbruch M, Klaucic A, Plewig G (1997) Photo hen’s egg test: a model for phototoxicity. Br J Dermatol 136:326–330

    Article  PubMed  CAS  Google Scholar 

  28. Ferguson J, Johnson BE (1993) Clinical and laboratory studies of the photosensitizing potential of norfloxacin, a 4-quinolone broad-spectrum antibiotic. Br J Dermatol 128:285–295

    PubMed  CAS  Google Scholar 

  29. Diffey BL, Daymond TJ, Fairgreaves H (1983) Phototoxic reactions to piroxicam, naproxen and tiaprofenic acid. Br J Rheumatol 22:239–242

    PubMed  CAS  Google Scholar 

  30. Ljunggren B (1985) Propionic acid-derived nonsteroidal anti-inflammatory drugs and phototoxicity in vitro. Photodermatology 2:3–9

    PubMed  CAS  Google Scholar 

  31. Stern RS (1983) Phototoxic-reactions to piroxicam and other non-steroidal anti-inflammatory agents. N Engl J Med 309:186–187

    PubMed  CAS  Google Scholar 

  32. Ferguson J, Addo HA, Jones S, Johnson BE, Frain-Bell W (1985) A study of cutaneous photosensitivity induced by amiodarone. Br J Dermatol 113:537–549

    PubMed  CAS  Google Scholar 

  33. Elmets CA (1986) Drug-induced photoallergy. Dermatol Clin 4:231–241

    PubMed  CAS  Google Scholar 

  34. Emmett EA (1978) Drug photoallergy. Int J Dermatol 17:370–379

    Article  PubMed  CAS  Google Scholar 

  35. Horio T (1984) Photoallergic reaction. Classification and pathogenesis. Int J Dermatol 23:376–382

    PubMed  CAS  Google Scholar 

  36. Schurer NY, Holzle E, Plewig G, Lehmann P (1992) Photosensitivity induced by quinidine sulfate: experimental reproduction of skin lesions. Photodermatol Photoimmunol Photomed 9:78–82

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Universitäts-Hautklinik Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany

    Renz Mang

  2. Heinrich-Heine University Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Germany

    Helger Stege

  3. Institut für umweltmedizinische Forschung, Auf’ m Hennekamp 50, 40225, Düsseldorf, Germany

    Jean Krutmann

Authors
  1. Renz Mang
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Helger Stege
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Jean Krutmann
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Klinikum Dortmund gGmbH, Hautklinik Lehrstuhl Dermatologie der Universität Witten/Herdecke, Beurhausstr. 40, 44137, Dortmund, Germany

    Peter J. Frosch (Professor) (Professor)

  2. Dermatologisk afdeling K, Amtssygehuset Gentofte, 2900, Hellerup, Denmark

    Torkil Menné (Professor Dr.) (Professor Dr.)

  3. Laboratoire de Dermato-Chimie Clinique Dermatologique, CHU, 67091, Strasbourg Cedex, France

    Jean-Pierre Lepoittevin (Professor) (Professor)

Rights and permissions

Reprints and permissions

Copyright information

© 2006 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Mang, R., Stege, H., Krutmann, J. (2006). Mechanisms of Phototoxic and Photoallergic Reactions. In: Frosch, P.J., Menné, T., Lepoittevin, JP. (eds) Contact Dermatitis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-31301-X_6

Download citation

  • DOI: https://doi.org/10.1007/3-540-31301-X_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-24471-4

  • Online ISBN: 978-3-540-31301-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation