Use of Tylan 200® for the treatment of mastitis caused by Staphylococcus aureus and/or Streptococcus uberis

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Abstract

Staphylococcus aureus and Streptococcus uberis are leading causes of cattle mastitis. In the field these pathogens are typically treated with the macrolide tylosin, in the form of Tylan 200®. The aim of the study was to determine the Minimum Inhibitory Concentration (MIC) of Tylosin against S. aureus and S. uberis using the methodology recommended by the Clinical and Laboratory Standards Institute (CLSI). A total of 50 isolates each of S. aureus and S. uberis were collected from cattle with clinical mastitis and subjected to antibiotic susceptibility testing.