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Adiponectin and the Cardiovascular System

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Book cover Diabetes and Cardiovascular Disease

Part of the book series: Contemporary Cardiology ((CONCARD))

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Abstract

Adiponectin, a recently discovered protein produced exclusively by adipocytes, is thought to be a possible mediator between obesity, insulin resistance, and cardiovascular disease (CVD). Although its function is not entirely known, body fat distribution, insulin, sex hormones, tumor necrosis factor (TNF)-α, and peroxisome proliferator-activated receptor (PPAR)-α may contribute to its regulation. Along with being associated with cardiovascular risk factors such as diabetes and dyslipidemia, deficiency in adiponectin may also directly compromise endothelial action and promote atherosclerosis.

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Authors and Affiliations

  1. Division of Endocrinology and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Suketu Shah MD

  2. Division of Endocrinology and Metabolism, Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, MA

    Alina Gavrila MD & Christos S. Mantzoros MD

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  1. Suketu Shah MD
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  2. Alina Gavrila MD
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  3. Christos S. Mantzoros MD
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Editors and Affiliations

  1. Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA

    Michael T. Johnstone MD, CM, FRCP(C)  & Aristidis Veves MD, DSC  & 

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Shah, S., Gavrila, A., Mantzoros, C.S. (2005). Adiponectin and the Cardiovascular System. In: Johnstone, M.T., Veves, A. (eds) Diabetes and Cardiovascular Disease. Contemporary Cardiology. Humana Press. https://doi.org/10.1385/1-59259-908-7:191

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  • DOI: https://doi.org/10.1385/1-59259-908-7:191

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