Abstract
There are as many as 1 billion individuals with hypertension worldwide and physicians have only four recommended antihypertensive drugs to treat this varied population of patients. More than 50 million Americans have hypertension, and at ages 65–75 more than 60% of individuals have hypertension. The incidence is higher in African Americans.
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ALLH AT Officers and Coordinators for the ALLHAT Collaborative Research Group. The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial. Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002;288:2981–2997.
Aram V, Chobanian MD, Bakris GL, et al. and the National High Blood Pressure Education Program Coordinating Committee. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and the Treatment of High Blood Pressure. The JNC 7 Report. JAMA 2003;289:2560–2571.
Bakris GL, Fonseca V, Katholi RE, et al. for the GEMINI Investigators. Metabolic effects of carvedilol vs metoprolol in patients with type 2 diabetes mellitus and hypertension: a randomized controlled trial. JAMA 2004;292:2227–2236.
Bennet NE. Hypertension in the elderly. Lancet 1994;344:447.
Black HR, Elliott WJ, Grandits G, et al., CONVINCE Research Group. Principal results of the Controlled Onset Verapamil Investigation of Cardiovascular End Points (CONVINCE) trial. JAMA 2003;289:2073–2082
Carlberg B, Samuelsso O, Lindholm LH. Atenolol in hypertension: is it a wise choice? Lancet 2004;364:1684–1689.
Cominacini L, Fratta Pasini A, Garbin U, et al. Nebivolol and its 4-keto derivative increase nitric oxide in endothelial cells by reducing its oxidative inactivation. J Am Coll Cardiol 2003;42:1838–1844.
Committee on Detection, Evaluation and Treatment of High Blood Pressure. The seventh report of the Joint National Committee on Detection, Evaluation and Treatment of High Blood Pressure (JNCV). Arch Intern Med 2003.
Crow RS, Prineas RJ, Routaharju P, et al. Relation between electrocardiography and echocardiography for left ventricular mass in mild systemic hypertension (Results from Treatment of Mild Hypertension Study). Am J Cardiol 1995;75:1233.
Cunningham FG, Lindheimer MD. Current concepts: hypertension inpregnancy. N Engl J Med 1992;326:927.
Dabaghi S. ACE inhibitors and pancreatitis. Ann Intern Med 1991;115:331.
Edelson JF, Weinstein MC, Tosteson ANA, et al. Long-term cost-effectiveness of various initial monotherapies for mild to moderate hypertension. JAMA 1990;263:408.
Felson DT, Sloutskis D, Anderson JJ, et al. Thiazide diuretics and the risk of hip fracture. Results from the Framingham Study. JAMA 1991;265:370.
Franco V, Oparil S, Carretero OA. Hypertensive therapy: part II. Circulation 2004;109:3081–3088.
Furberg CD, Psaty BM, Meyer JV. Nifedipine: dose-related increase in mortality in patients with coronary heart disease. Circulation 1995;92:1326.
Giannoccaro PJ, Wallace GJ, Higginson LAJ, et al. Fatal angioedema associated with enalapril. Can J Cardiol 1989;5:335.
Hanson MW, Feldman JM, Beam CA, et al. Iodine 131-labeled metaiodobenzylguanidine scintigraphy and biochemical analyses in suspected pheochromocytoma. Arch Intern Med 1991;151:1397.
Hartman RP, Kawashima A, King F. Evaluation of renal causes of hypertension Radiol Clin N Am 2003;41:909.
Kario K, Pickering TG, Umeda Y, et al. Morning surge in blood pressure as a predictor of silent and clinical cerebrovascular disease in elderly hypertensives: a prospective study. Circulation 2003;107:1401–1406.
Khan M Gabriel. Hypertension. In: Cardiac Drug Therapy. Sixth edition. Philadelphia: WB Saunders, 2003.
Lakshman MR, Reda DJ, Materson B J, et al, for the Department of Veterans Affairs Cooperative Study Group on Antihypertensive Agents. Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension. Arch Intern Med 1999;159:551–558.
Lucas MJ, Leveno KJ, Cunningham FG. A comparison of magnesium sulfate with phenytoin for the prevention of eclampsia. N Engl J Med 1995;333:201.
Lunde H, Hedner T, Samuelsson O, et al. Dyspnoea, asthma, and bronchospasm in relation to treatment with angiotensin converting enzyme inhibitors. BMJ 1994;308:18.
Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group. JAMA 2000;283:1967–1975.
Materson BJ, Reda DJ, Cushman WC. Single drug therapy for hypertension in men: a comparison of six antihypertensive agents with placebo. N Engl J Med 1993;328:914.
Mattioli AV, Zennaro M, Bonatti S, et al. Regression of left ventricular hypertrophy and improvement of diastolic function in hypertensive patients treated with telmisartan. Int J Cardiol 2004;97(3):383–388.
Nissen SE, Tuzcu EM, Libby P, et al. for the CAMELOT Investigators. Effect of Antihypertensive Agents on Cardiovascular Events in Patients with Coronary Disease and Normal Blood Pressure: The CAMELOT Study: a randomized controlled trial. JAMA 2004;292:2217–2225.
Panacek EA, Bednarxzyk EM, Dunbar LM, et al. Randomized prospective trial of fenoldopam versus sodium nitroprusside in the treatment of acute severe hypertension. Acad Emerg Med 1995;2:959.
Parks WJ, Thang DM, Plauth WH, et al. Incidence of aneurysm formation after dacron patch aortoplasty repair for coarctation of the aorta: long-term results and assessment utilizing magnetic resonance angiography with three-dimensional surface rendering. J Am Coll Cardiol 1995;26:266.
Pearson AC, Pasierski T, Labovitz AJ. Left ventricular hypertrophy: diagnosis, prognosis and management. Am Heart J 1991;121:148.
Pepine CJ. What is the optimal blood pressure and drug therapy for patients with coronary artery disease? JAMA 2004;292:2271–2273.
Pitt B, Reichek N, Willenbrock R, et al. Effects of eplerenone, enalapril, and eplerenone/enalapril in patients with essential hypertension and left ventricular hypertrophy: the 4E-left ventricular hypertrophy study. Circulation. 2003;108:1831–1838.
Salathe M, Weiss P, Ritz R. Rapid reversal of heart failure in a patient with pheochromocytoma and catecholamine-induced cardiomyopathy who was treated with captopril. Br Heart J 1992;68:527.
SHEP Cooperative Study Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension: final results of the Systolic Hypertension in the Elderly Programs (SHEP). JAMA 1991;265:3255.
Slater EE, Merrill DD, Guess HA, et al. Clinical profile of angioedema associated with angiotensin converting enzyme inhibition. JAMA 1988;260:967.
Szlachcic J, Tubau JF, O’Kelly B, et al. What is the role of silent coronary artery disease and left ventricular hypertrophy in the genesis of ventricular arrhythmias in men with essential hypertension? J Am Coll Cardiol 1992;19:803.
The Treatment of Mild Hypertension Research Group. The treatment of mild hypertension study. A randomized, placebo-controlled trial of a nutritional-hygienic regimen along with various drug monotherapies. Arch Intern Med 1991;151:1413.
UK prospective Diabetes study group. Efficacy of atenolol and captopril in reducing risk of microvascular and macrovascular complications in Type II diabetes: UKPDS. BMJ 1998;317:713.
Wassertheil-Smoller S, Blaufox D, Oberman A, et al. Effect of anti-hypertensives on sexual function and quality of life: the TAIM Study. Ann Intern Med 1991;114:613.
Wilkstrand J, Warnold I, Tuomilhto J, et al. Metoprolol versus thiazide diuretics in hypertension. Morbidity results from the MAPHY Study. Hypertension 1991;17:579.
Wood SM, Mann RD, Rawlins MD. Angioedema and urticaria associated with angiotensin converting enzyme inhibitors. Br Med J 1987;294:91.
Yusuf S. Calcium antagonists in coronary artery disease and hypertension: time for reevaluation? Circulation 1995;92:1079.
Yusuf S, Gerstein H, Hoogwerf B, et al, for the HOPE Study Investigators. Ramipril and the development of diabetes. JAMA 2001;286:1882–1885.
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(2005). Hypertension. In: Heart Disease Diagnosis and Therapy. Contemporary Cardiology. Humana Press. https://doi.org/10.1385/1-59259-868-4:299
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DOI: https://doi.org/10.1385/1-59259-868-4:299
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