Cytogenetics of Infertility

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Abstract

The World Health Organization has described infertility as a health problem of global concern. One in seven couples experiences infertility or subfertility (1). Infertility is commonly defined as absence of a pregnancy after a year of unprotected intercourse. For information about cytogenetic aspects of spontaneous abortions, please refer to Chapter 13. Male factor and female factor infertility each account for about 40% of cases of infertility, and the remaining 20% is a combination (2). In this chapter, an overview of known causes of infertility will be presented so that the cytogenetic component’s relative contribution can be placed into context.