Dengue Virus

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Abstract

Dengue is the most frequently reported human viral disease transmitted by arthropod vectors. The disease is endemic in most tropical and subtropical areas; over half of the world’s population lives in locations that are at risk for transmission (Fig. 1). Worldwide, there are an estimated 50–100 million cases of dengue and 250,000–500,000 cases of dengue hemorrhagic fever (DHF) annually. During the last few decades, dengue epidemics have been reported in countries that had not previously been considered endemic (1). This chapter provides a brief review of the clinical and laboratory features of dengue and DHF, a detailed discussion of dengue infection during pregnancy, and specific characteristics of dengue during the perinatal period.