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Rare Event Cell Surging in a Microfluidic System for Application in Prenatal Diagnosis

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Abstract

A recently developed prototype of a microfluidic cell sorting system fabricated on silicon wafers using semiconductor technology is presented. Preliminary results show that we can successfully sort fluorescent particles from non-fluorescent particles. When the performance of the structure has been optimised we will initiate sorting of fluorescently labelled foetal cells. Sorting foetal cells from mother’s blood offers a safer alternative to currently used methods of prenatal genetic diagnostic screening that carry a substantial risk of harming the foetus and may even lead to pregnancy loss.

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References

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© 1998 Springer Science+Business Media Dordrecht

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Wolff, A., Larsen, U.D., Blankenstein, G., Philip, J., Telleman, P. (1998). Rare Event Cell Surging in a Microfluidic System for Application in Prenatal Diagnosis. In: Harrison, D.J., van den Berg, A. (eds) Micro Total Analysis Systems ’98. Springer, Dordrecht. https://doi.org/10.1007/978-94-011-5286-0_18

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  • DOI: https://doi.org/10.1007/978-94-011-5286-0_18

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-6225-1

  • Online ISBN: 978-94-011-5286-0

  • eBook Packages: Springer Book Archive

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