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Metastasis to Bone in Mammals

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Metastasis / Dissemination

Part of the book series: Cancer Growth and Progression ((CAGP,volume 8))

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Abstract

Tumor cell metastasis to the skeleton is a frequent complication of malignant disease. Only the lung and liver are more frequent sites of metastasis than bone. Moreover, the frequency of bone metastasis which is reported is an underestimate because many small bone metastases escape detection. Skeletal lesions are reported in 20% of all patients with advanced tumors and in more than 70% of patients with selected malignancies such as carcinoma of the breast (14, 43).

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Authors
  1. Donald R. Bertolini
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  2. Gregory R. Mundy
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Editors and Affiliations

  1. Pittsburgh Cancer Institute, Pittsburgh, Pa, USA

    Elizier L. Gorelik

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© 1989 Kluwer Academic Publishers, Dordrecht

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Bertolini, D.R., Mundy, G.R. (1989). Metastasis to Bone in Mammals. In: Gorelik, E.L. (eds) Metastasis / Dissemination. Cancer Growth and Progression, vol 8. Springer, Dordrecht. https://doi.org/10.1007/978-94-009-2534-2_9

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  • DOI: https://doi.org/10.1007/978-94-009-2534-2_9

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-94-010-7645-6

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