Abstract
In this section we report some pedigree fulfilling the clinical criteria established during two international consensus conferences on the behalf of the IGCLC (Caldas et al. 1999; Fitzgerald et al. 2010). These original kindred are collected from Italian regions, in particular from Tuscany, an high incidence area for GC risk (Roviello et al. 2007a; Corso et al. 2012).
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsAbbreviations
- IGCLC:
-
International Gastric Cancer Linkage Consortium
- GC:
-
Gastric Cancer
References
Birch JM, Hartley AL, Tricker KJ, Prosser J, Condie A, Kelsey AM, Harris M, Jones PH, Binchy A, Crowther D, Craft AW, Eden OB, Evans DGR, Thompson E, Mann JR, Martin J, Mitchell ELD, Santibanez-Koref MF (1994) Prevalence and diversity of constitutional mutations in the p53 gene among 21 Li-Fraumeni families. Cancer Res 54(5):1298–1304
Caldas C, Carneiro F, Lynch HT, Yokota J, Wiesner GL, Powell SM, Lewis FR, Huntsman DG, Pharoah PD, Jankowski JA, MacLeod P, Vogelsang H, Keller G, Park KG, Richards FM, Maher ER, Gayther SA, Oliveira C, Grehan N, Wight D, Seruca R, Roviello F, Ponder BA, Jackson CE (1999) Familial gastric cancer: overview and guidelines for management. J Med Genet 36(12):873–880. doi:10.1136/jmg.36.12.873
Corso G, Roviello F, Paredes J, Pedrazzani C, Novais M, Correia J, Marrelli D, Cirnes L, Seruca R, Oliveira C, Suriano G (2007) Characterization of the P373L E-cadherin germline missense mutation and implication for clinical management. Eur J Surg Oncol 33(9):1061–1067. doi:org/10.1016/j.ejso.2007.03.001
Corso G, Pedrazzani C, Marrelli D, Pinto E, Roviello F (2010) Familial gastric cancer and Li-Fraumeni syndrome. Eur J Cancer Care (Engl) 19(3):377–381. doi:10.1111/j.1365-2354.2008.01066.x
Corso G, Pedrazzani C, Pinheiro H, Fernandes E, Marrelli D, Rinnovati A, Pascale V, Seruca R, Oliveira C, Roviello F (2011) E-cadherin genetic screening and clinico-pathologic characteristics of early onset gastric cancer. Eur J Cancer 47(4):631–639. doi:org/10.1016/j.ejca.2010.10.011
Corso G, Marrelli D, Pascale V, Vindigni C, Roviello F (2012) Frequency of CDH1 germline mutations in gastric carcinoma coming from high- and low-risk areas: metanalysis and systematic review of the literature. BMC Cancer 12:8
Corso G, Roncalli F, Marrelli D, Carneiro F, Roviello F (2013) History, pathogenesis and management of familial gastric cancer: original study of John XXIII’s family. Biomed Res Int 2013:385132. doi:10.1155/2013/385132
Fitzgerald RC, Hardwick R, Huntsman D, Carneiro F, Guilford P, Blair V, Chung DC, Norton J, Ragunath K, Van Krieken JH, Dwerryhouse S, Caldas C, International Gastric Cancer Linkage Consortium (2010) Hereditary diffuse gastric cancer: updated consensus guidelines for clinical management and directions for future research. J Med Genet 47(7):436–444. doi:10.1136/jmg.2009.074237
Roviello F, Corso G, Pedrazzani C, Marrelli D, De Falco G, Suriano G, Vindigni C, Berardi A, Garosi L, De Stefano A, Leoncini L, Seruca R, Pinto E (2007a) High incidence of familial gastric cancer in Tuscany, a region in Italy. Oncology 72(3–4):243–247. doi:10.1159/000113015
Roviello F, Corso G, Pedrazzani C, Marrelli D, De Falco G, Berardi A, Garosi L, Suriano G, Vindigni C, De Stefano A, Leoncini L, Seruca R, Pinto E (2007b) Hereditary diffuse gastric cancer and E-cadherin: description of the first germline mutation in an Italian family. Eur J Surg Oncol 33(4):448–451. doi:10.1016/j.ejso.2006.10.028
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2013 Springer Science+Business Media Dordrecht
About this chapter
Cite this chapter
Corso, G. (2013). Appendix. In: Corso, G., Roviello, F. (eds) Spotlight on Familial and Hereditary Gastric Cancer. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-6570-2_17
Download citation
DOI: https://doi.org/10.1007/978-94-007-6570-2_17
Published:
Publisher Name: Springer, Dordrecht
Print ISBN: 978-94-007-6569-6
Online ISBN: 978-94-007-6570-2
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)