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Molecular Aspects of Iron Metabolism in Pathogenic and Symbiotic Plant-Microbe Associations pp 41–86Cite as

Mechanisms and Regulation of Iron Homeostasis in the Rhizobia

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Part of the book series: SpringerBriefs in Molecular Science ((SB BIOMETALS))

Abstract

Rhizobia are soil bacteria belonging to different genera whose most conspicuous characteristic is the ability to establish a symbiotic association with legumes and carry out nitrogen fixation. The success of these organisms in the rhizosphere or within the host plant involves the ability to sense the environment to assess the availability of nutrients, and to optimize cellular systems for their acquisition. Iron in natural habitats is mostly inaccessible due to low solubility, and microorganisms must compete for this limited nutrient. In addition to their agricultural and economic importance, rhizobia are model organisms that have given new insights into related, but less tractable animal pathogens. In particular, genetic control of iron homeostasis in the rhizobia and other α-Proteobacteria has moved away from the Fur paradigm to an iron sensing mechanism responding to the metal indirectly. Moreover, utilization of heme as an iron source is not unique to animal pathogens, and the rhizobial strategy reveals some interesting novel features. This chapter reviews advances in our understanding of iron metabolism in rhizobia.

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Acknowledgments

Research from the authors’ laboratories was supported by a grant from PEDECIBA-Uruguay to E.F., NIH grants GM067966 and GM099667 to M.R.O’B.

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  1. Departmento de Bioquímica y Genómica Microbianas, Instituto de Investigaciones Biológicas Clemente Estable, Av. Italia 3318, 11600, Montevideo, Uruguay

    Elena Fabiano

  2. Department of Biochemistry, State University of New York at Buffalo, 140 Farber Hall, Buffalo, NY, 14214, USA

    Mark R. O’Brian

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  1. Elena Fabiano
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  2. Mark R. O’Brian
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Correspondence to Elena Fabiano or Mark R. O’Brian .

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  1. , Interactions Plantes-Pathogenes, AgroParis Tech, rue Claude Bernard 16, Paris, 75005, France

    Dominique Expert

  2. , Department of Biochemistry, State University of New York at Buffalo, Farber Hall 140, Buffalo, 14214, New York, USA

    Mark R. O'Brian

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© 2012 The Author(s)

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Fabiano, E., O’Brian, M.R. (2012). Mechanisms and Regulation of Iron Homeostasis in the Rhizobia. In: Expert, D., O'Brian, M. (eds) Molecular Aspects of Iron Metabolism in Pathogenic and Symbiotic Plant-Microbe Associations. SpringerBriefs in Molecular Science(). Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5267-2_3

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