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Ions in Water and Biophysical Implications pp 171–203Cite as

Biophysical Implications

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Abstract

The properties of water and of ions and their mutual effects in bulk solutions and at interfaces described in the previous chapters lead to a discussion of the biophysical implications that ions in water have. The terms chaotropic (structure-breaking) and kosmotropic (structure-making) applied to aqueous ions relate to homogeneous solutions and should not be called on when dealing with bio-molecules that present surfaces in the solution. For such cases the empirical Hofmeister series of anions and of cations are appropriately descriptive, but should not be applied to situations that do not involve surfaces. When appropriately applied, the Hofmeister series of ions still elude understanding, since many different effects that depend not only on the ions but also on the substrates affected by them play a role. Some comments on items involving aqueous ions and biomolecules are added, such as the behaviour of guanidinium ions, the hydration of proteins, and the specificity of sodium and potassium channels.

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    Yizhak Marcus

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Marcus, Y. (2012). Biophysical Implications. In: Ions in Water and Biophysical Implications. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4647-3_5

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