Skip to main content

Contraception and Cancer Treatment in Young Persons

  • Chapter
  • First Online:
Reproductive Health and Cancer in Adolescents and Young Adults

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 732))

Abstract

Adolescence and young adulthood can be an extremely stressful time for all concerned. When this period is compounded by the development of cancer, formidable and seemingly insurmountable problems may be perceived. With an annual incidence rate in western populations of around 250–300 per million, cancer in adolescents and young adults (AYAs) is relatively uncommon. In the western countries, five-year survival of patients diagnosed around 1990 exceeded 70%; therefore, many AYAs with cancer may remain fertile. Further advances in therapeutic modalities are creating a generation of AYAs with cancer who can now aspire to the same sexual and reproductive activities as their healthy peers. This then raises the issue of avoidance of undesired pregnancy during and after treatment. This chapter aims to address the contraceptive needs of AYAs undergoing treatment for cancer.

I always thought my patients were too sick to even think about sex. I had a twenty-one year old male patient who was so weak from chemo he had to use a wheelchair. Halfway into his treatment he told me his girlfriend was pregnant and he couldn’t understand how. I’d talked to him and his parents about the need to sperm bank and so he thought he didn’t need to use protection. It was a difficult situation because he also managed to get chlamydia in the process.

Dr. B, Oncologist

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Bleyer A, Viny A, Barr R (2006) Cancer in 15- to 29-year-olds by primary site. Oncologist 11(6):590–601

    PubMed  Google Scholar 

  2. Wu XC, Chen VW, Steele B, Roffers S, Klotz JB, Correa CN, Carozza SE (2003) Cancer incidence in adolescents and young adults in the United States, 1992–1997. J Adolesc Health 32(6):405–415

    PubMed  Google Scholar 

  3. Chapter: Smith MA, Gloecler-Ries LA (2002) Childhood cancer: incidence, survival and mortality. In: Pizzo PA, Poplack DG (eds) Principles and practice of pediatric oncology. Williams and Wilkins, Philadelphia, Lippincot pp 1–12.

    Google Scholar 

  4. Byrne J, Mulvihill JJ, Myers MH, Connelly RR, Naughton MD, Krauss MR, Steinhorn SC, Hassinger DD, Austin DF, Bragg K et al (1987) Effects of treatment on fertility in long-term survivors of childhood or adolescent cancer. N Engl J Med 317(21):1315–1321

    PubMed  CAS  Google Scholar 

  5. Wallace WH, Anderson RA, Irvine DS (2005) Fertility preservation for young patients with cancer: who is at risk and what can be offered? Lancet Oncol 6(4):209–218

    PubMed  Google Scholar 

  6. Cvancarova M, Samuelsen SO, Magelssen H, Fossa SD (2009) Reproduction rates after cancer treatment: experience from the Norwegian radium hospital. J Clin Oncol 27(3):334–343

    PubMed  Google Scholar 

  7. Coupey SM, Alderman EM (1992) Sexual behavior and related health care for adolescents with chronic medical illness. Adolesc Med 3(2):317–330

    PubMed  Google Scholar 

  8. Suris JC, Resnick MD, Cassuto N, Blum RW (1996) Sexual behavior of adolescents with chronic disease and disability. J Adolesc Health 19(2):124–131

    PubMed  CAS  Google Scholar 

  9. Blum RW (1997) Sexual health contraceptive needs of adolescents with chronic conditions. Arch Pediatr Adolesc Med 151(3):290–297

    PubMed  CAS  Google Scholar 

  10. Morgan S, Davies S, Palmer S, Plaster M (2010) Sex, drugs, and rock ‘n’ roll: caring for adolescents and young adults with cancer. J Clin Oncol 28(32):4825–4830

    Google Scholar 

  11. Gbolade BA (2000) Teenage pregnancy rates and the age and sex of general practitioners. Record linkage analysis could have been used. BMJ 321(7257):381–382; author reply 382–383

    PubMed  CAS  Google Scholar 

  12. World Health Organization (2009) Improving access to quality care in family planning: medical eligibility criteria for contraceptive use, 4th edn. WHO, Geneva, Switzerland

    Google Scholar 

  13. Schwarz EB, Hess R, Trussell J (2009) Contraception for cancer survivors. J Gen Intern Med 24(Suppl 2):S401–S406

    PubMed  Google Scholar 

  14. Jemmott JB 3rd, Jemmott LS, Fong GT (1998) Abstinence and safer sex HIV risk-reduction interventions for African American adolescents: a randomized controlled trial. JAMA 279(19):1529–1536

    PubMed  Google Scholar 

  15. Greydanus DE, Patel DR, Rimsza ME (2001) Contraception in the adolescent: an update. Pediatrics 107(3):562–573

    PubMed  CAS  Google Scholar 

  16. Lara-Torre E (2009) Update in adolescent contraception. Obstet Gynecol Clin North Am 36(1):119–128

    PubMed  Google Scholar 

  17. Grinyer A (2002) Sexuality and fertility: confronting the “taboo”. In: Clarke D (ed) Cancer in young adults: through parent’s eyes. Open University Press, Buckingham-Philadelphia, pp 61–75

    Google Scholar 

  18. Rieder J, Coupey SM (1999) The use of nonhormonal methods of contraception in adolescents. Pediatr Clin North Am 46(4):671–694

    PubMed  CAS  Google Scholar 

  19. Schwarz EB, Sobota M, Charron-Prochownik D (2010) Perceived access to contraception among adolescents with diabetes: barriers to preventing pregnancy complications. Diab Educ 36(3):489–494

    Google Scholar 

  20. Schwarz EB, Manzi S (2008) Risk of unintended pregnancy among women with systemic lupus erythematosus. Arthritis Rheum 59(6):863–866

    PubMed  Google Scholar 

  21. Wilcox AJ, Weinberg CR, Baird DD (1995) Timing of sexual intercourse in relation to ovulation. Effects on the probability of conception, survival of the pregnancy, and sex of the baby. N Engl J Med 333(23):1517–1521

    PubMed  CAS  Google Scholar 

  22. Dunson DB, Baird DD, Wilcox AJ, Weinberg CR (1999) Day-specific probabilities of clinical pregnancy based on two studies with imperfect measures of ovulation. Hum Reprod 14(7):1835–1839

    PubMed  CAS  Google Scholar 

  23. Wilcox AJ, Weinberg CR, Baird DD (1998) Post-ovulatory ageing of the human oocyte and embryo failure. Hum Reprod 13(2):394–397

    PubMed  CAS  Google Scholar 

  24. Wilcox AJ, Dunson D, Baird DD (2000) The timing of the “fertile window” in the menstrual cycle: day specific estimates from a prospective study. BMJ 321(7271):1259–1262

    PubMed  CAS  Google Scholar 

  25. Kost K, Singh S, Vaughan B, Trussell J, Bankole A (2008) Estimates of contraceptive failure from the 2002 National Survey of Family Growth. Contraception 77(1):10–21

    PubMed  Google Scholar 

  26. Fruzzetti F, Bitzer J (2010) Review of clinical experience with estradiol in combined oral contraceptives. Contraception 81(1):8–15

    Google Scholar 

  27. Palacios S, Wildt L, Parke S, Machlitt A, Romer T, Bitzer J (2010) Efficacy and safety of a novel oral contraceptive based on oestradiol (oestradiol valerate/dienogest): a Phase III trial. Eur J Obstet Gynecol Reprod Biol 149(1):57–62

    Google Scholar 

  28. Sitruk-Ware R, Nath A (2010) The use of newer progestins for contraception. Contraception 82(5):410–417

    Google Scholar 

  29. Gerschultz KL, Sucato GS, Hennon TR, Murray PJ, Gold MA (2007) Extended cycling of combined hormonal contraceptives in adolescents: physician views and prescribing practices. J Adolesc Health 40(2):151–157

    PubMed  Google Scholar 

  30. Trussell J, Hatcher RA, Cates W Jr, Stewart FH, Kost K (1990) Contraceptive failure in the United States: an update. Stud Fam Plann 21(1):51–54

    PubMed  CAS  Google Scholar 

  31. Brooks TL, Shrier LA (1999) An update on contraception for adolescents. Adolesc Med 10(2):211–219, v

    PubMed  CAS  Google Scholar 

  32. Szarewski A (2002) High acceptability and satisfaction with NuvaRing use. Eur J Contracept Reprod Health Care 7(Suppl 2):31–36; discussion 37–39

    PubMed  Google Scholar 

  33. Audet MC, Moreau M, Koltun WD, Waldbaum AS, Shangold G, Fisher AC, Creasy GW (2001) Evaluation of contraceptive efficacy and cycle control of a transdermal contraceptive patch vs an oral contraceptive: a randomized controlled trial. JAMA 285(18):2347–2354

    PubMed  CAS  Google Scholar 

  34. Raine TR, Epstein LB, Harper CC, Brown BA, Boyer CB (2009) Attitudes toward the vaginal ring and transdermal patch among adolescents and young women. J Adolesc Health 45(3):262–267

    PubMed  Google Scholar 

  35. Stewart FH, Brown BA, Raine TR, Weitz TA, Harper CC (2007) Adolescent and young women’s experience with the vaginal ring and oral contraceptive pills. J Pediatr Adolesc Gynecol 20(6):345–351

    PubMed  Google Scholar 

  36. Kouides PA, Kadir RA (2007) Menorrhagia associated with laboratory abnormalities of hemostasis: epidemiological, diagnostic and therapeutic aspects. J Thromb Haemost 5(Suppl 1):175–182

    PubMed  CAS  Google Scholar 

  37. Coffee AL, Sulak PJ, Kuehl TJ (2007) Long-term assessment of symptomatology and satisfaction of an extended oral contraceptive regimen. Contraception 75(6):444–449

    PubMed  Google Scholar 

  38. Owens K, Honebrink A (1999) Gynecologic care of medically complicated adolescents. Pediatr Clin North Am 46(3):631–642, ix.

    PubMed  CAS  Google Scholar 

  39. Gold MA (1999) Prescribing and managing oral contraceptive pills and emergency contraception for adolescents. Pediatr Clin North Am 46(4):695–718

    PubMed  CAS  Google Scholar 

  40. Cole JA, Norman H, Doherty M, Walker AM (2007) Venous thromboembolism, myocardial infarction, and stroke among transdermal contraceptive system users. Obstet Gynecol 109(2 Pt 1):339–346

    PubMed  Google Scholar 

  41. Rice CF, Killick SR, Dieben T, Coelingh Bennink H (1999) A comparison of the inhibition of ovulation achieved by desogestrel 75 micrograms and levonorgestrel 30 micrograms daily. Hum Reprod 14(4):982–985

    PubMed  CAS  Google Scholar 

  42. Korver T, Klipping C, Heger-Mahn D, Duijkers I, van Osta G, Dieben T (2005) Maintenance of ovulation inhibition with the 75-microg desogestrel-only contraceptive pill (Cerazette) after scheduled 12-h delays in tablet intake. Contraception 71(1):8–13

    PubMed  CAS  Google Scholar 

  43. de Melo NR (2010) Estrogen-free oral hormonal contraception: benefits of the progestin-only pill. Womens Health (Lond Engl) 6(5):721–735

    Google Scholar 

  44. Plu-Bureau G, Horellou MH (2008) Therapeutic management of menometrorrhagia in hemostasis disorders. J Gynecol Obstet Biol Reprod (Paris) 37(Suppl 8):S365–367

    Google Scholar 

  45. Ottesen S, Narring F, Renteria SC, Michaud PA (2002) Emergency contraception among teenagers in Switzerland: a cross-sectional survey on the sexuality of 16- to 20-year-olds. J Adolesc Health 31(1):101–110

    PubMed  Google Scholar 

  46. Task Force of Postovulatory Methods of Fertility Regulation (1998) Randomised controlled trial of levonorgestrel versus the Yuzpe regimen of combined oral contraceptives for emergency contraception. Task Force on Postovulatory Methods of Fertility Regulation. Lancet 352(9126):428–433

    Google Scholar 

  47. Hewitt G, Cromer B (2000) Update on adolescent contraception. Obstet Gynecol Clin North Am 27(1):143–162

    PubMed  CAS  Google Scholar 

  48. Glasier AF, Cameron ST, Fine PM, Logan SJ, Casale W, Van Horn J, Sogor L, Blithe DL, Scherrer B, Mathe H et al (2010) Ulipristal acetate versus levonorgestrel for emergency contraception: a randomised non-inferiority trial and meta-analysis. Lancet 375(9714):555–562

    Google Scholar 

  49. Haynes KA (2007) An update on emergency contraception use in adolescents. J Pediatr Nurs 22(3):186–195

    PubMed  Google Scholar 

  50. Raine TR, Harper CC, Rocca CH, Fischer R, Padian N, Klausner JD, Darney PD (2005) Direct access to emergency contraception through pharmacies and effect on unintended pregnancy and STIs: a randomized controlled trial. JAMA 293(1):54–62

    PubMed  CAS  Google Scholar 

  51. Grimes DA, Lopez LM, Manion C, Schulz KF (2007) Cochrane systematic reviews of IUD trials: lessons learned. Contraception 75(6 Suppl):S55–59

    PubMed  Google Scholar 

  52. Lande RF (1995). New era for injectables. Population Reports, Series K, No. 5. Baltimore, Johns Hopkins School of Public Health, Population Information Program, August

    Google Scholar 

  53. Belsey EM (1988) Vaginal bleeding patterns among women using one natural and eight hormonal methods of contraception. Contraception 38(2):181–206

    PubMed  CAS  Google Scholar 

  54. Scholes D, Lacroix AZ, Ott SM, Ichikawa LE, Barlow WE (1999) Bone mineral density in women using depot medroxyprogesterone acetate for contraception. Obstet Gynecol 93(2):233–238

    PubMed  CAS  Google Scholar 

  55. Cromer BA, Blair JM, Mahan JD, Zibners L, Naumovski Z (1996) A prospective comparison of bone density in adolescent girls receiving depot medroxyprogesterone acetate (Depo-Provera), levonorgestrel (Norplant), or oral contraceptives. J Pediatr 129(5):671–676

    PubMed  CAS  Google Scholar 

  56. Harel Z, Cromer B (1999) The use of long-acting contraceptives in adolescents. Pediatr Clin North Am 46(4):719–732

    PubMed  CAS  Google Scholar 

  57. Busen NH, Britt RB, Rianon N (2003) Bone mineral density in a cohort of adolescent women using depot medroxyprogesterone acetate for one to two years. J Adolesc Health 32(4):257–259

    PubMed  Google Scholar 

  58. Lara-Torre E, Edwards CP, Perlman S, Hertweck SP (2004) Bone mineral density in adolescent females using depot medroxyprogesterone acetate. J Pediatr Adolesc Gynecol 17(1):17–21

    PubMed  Google Scholar 

  59. Meier C, Brauchli YB, Jick SS, Kraenzlin ME, Meier CR (2010) Use of depot medroxyprogesterone acetate and fracture risk. J Clin Endocrinol Metab 95(11):4909–4916

    Google Scholar 

  60. Matkovic V, Jelic T, Wardlaw GM, Ilich JZ, Goel PK, Wright JK, Andon MB, Smith KT, Heaney RP (1994) Timing of peak bone mass in Caucasian females and its implication for the prevention of osteoporosis. Inference from a cross-sectional model. J Clin Invest 93(2):799–808

    PubMed  CAS  Google Scholar 

  61. Leiper AD (1998) Osteoporosis in survivors of childhood malignancy. Eur J Cancer 34(6):770–772

    PubMed  CAS  Google Scholar 

  62. Arikoski P, Komulainen J, Riikonen P, Parviainen M, Jurvelin JS, Voutilainen R, Kroger H (1999) Impaired development of bone mineral density during chemotherapy: a prospective analysis of 46 children newly diagnosed with cancer. J Bone Miner Res 14(12):2002–2009

    PubMed  CAS  Google Scholar 

  63. Meirik O (2002) Implantable contraceptives for women. Contraception 65(1):1–2

    PubMed  Google Scholar 

  64. Glasier A (2002) Implantable contraceptives for women: effectiveness, discontinuation rates, return of fertility, and outcome of pregnancies. Contraception 65(1):29–37

    PubMed  Google Scholar 

  65. Blumenthal PD, Gemzell-Danielsson K, Marintcheva-Petrova M (2008) Tolerability and clinical safety of Implanon. Eur J Contracept Reprod Health Care 13(Suppl 1):29–36

    PubMed  CAS  Google Scholar 

  66. Berenson AB, Wiemann CM (1995) Use of levonorgestrel implants versus oral contraceptives in adolescence: a case-control study. Am J Obstet Gynecol 172(4 Pt 1):1128–1135; discussion 1135–1127

    PubMed  CAS  Google Scholar 

  67. Weisman CS, Plichta SB, Tirado DE, Dana KH (1993) Comparison of contraceptive implant adopters and pill users in a family planning clinic in Baltimore. Fam Plann Perspect 25(5):224–226

    PubMed  CAS  Google Scholar 

  68. Ammerman SD (1995) The use of Norplant and Depo Provera in adolescents. J Adolesc Health 16(5):343–346

    PubMed  CAS  Google Scholar 

  69. Cullins VE, Huggins GR (2000). Adolescent contraception and abortion. In: Koehler-Carpenter SE, Rock JA (eds) Pediatric and adolescent oncology. Williams and Wilkins, Philadelphia, Lippincott, pp 364–392

    Google Scholar 

  70. Kothari AS, Beechey-Newman N, D’Arrigo C, Hanby AM, Ryder K, Hamed H, Fentiman IS (2002) Breast carcinoma in women age 25 years or less. Cancer 94(3):606–614

    PubMed  Google Scholar 

  71. Perez-Gracia JL, Carrasco EM (2002) Tamoxifen therapy for ovarian cancer in the adjuvant and advanced settings: systematic review of the literature and implications for future research. Gynecol Oncol 84(2):201–209

    PubMed  CAS  Google Scholar 

  72. Osterlind A, Tucker MA, Stone BJ, Jensen OM (1988) The Danish case-control study of cutaneous malignant melanoma. III. Hormonal and reproductive factors in women. Int J Cancer 42(6):821–824

    PubMed  CAS  Google Scholar 

  73. Hubacher D (2007) Copper intrauterine device use by nulliparous women: review of side effects. Contraception 75(6 Suppl):S8–11

    PubMed  CAS  Google Scholar 

  74. Kadir RA, Chi C (2007) Levonorgestrel intrauterine system: bleeding disorders and anticoagulant therapy. Contraception 75(6 Suppl):S123–129

    PubMed  CAS  Google Scholar 

  75. Prager S, Darney PD (2007) The levonorgestrel intrauterine system in nulliparous women. Contraception 75(6 Suppl):S12–15

    PubMed  CAS  Google Scholar 

  76. Trussell J, Strickler J, Vaughan B (1993) Contraceptive efficacy of the diaphragm, the sponge and the cervical cap. Fam Plann Perspect 25(3):100–105, 135.

    PubMed  CAS  Google Scholar 

  77. Mauck CK, Weiner DH, Creinin MD, Archer DF, Schwartz JL, Pymar HC, Ballagh SA, Henry DM, Callahan MM (2006) FemCap with removal strap: ease of removal, safety and acceptability. Contraception 73(1):59–64

    PubMed  Google Scholar 

  78. Rosenberg MJ, Gollub EL (1992) Commentary: methods women can use that may prevent sexually transmitted disease, including HIV. Am J Public Health 82(11):1473–1478

    PubMed  CAS  Google Scholar 

  79. Edelman DA, McIntyre SL, Harper J (1984) A comparative trial of the today contraceptive sponge and diaphragm. Am J Obstet Gynecol 150(7):869–876

    PubMed  CAS  Google Scholar 

  80. McIntyre SL, Higgins JE (1986) Parity and use-effectiveness with the contraceptive sponge. Am J Obstet Gynecol 155(4):796–801

    PubMed  CAS  Google Scholar 

  81. Daly CC, Helling-Giese GE, Mati JK, Hunter DJ (1994) Contraceptive methods and the transmission of HIV: implications for family planning. Genitourin Med 70(2):110–117

    PubMed  CAS  Google Scholar 

  82. Bounds W, Guillebaud J, Newman GB (1992) Female condom (Femidom): a clinical study of its use-effectiveness and patient acceptability. Br J Fam Plann18:36–41

    Google Scholar 

  83. Smit J, Beksinska M, Vijayakumar G, Mabude Z (2006) Short-term acceptability of the Reality polyurethane female condom and a synthetic latex prototype: a randomized crossover trial among South African women. Contraception 73(4):394–398

    PubMed  Google Scholar 

  84. Minnis AM, Padian NS (2005) Effectiveness of female controlled barrier methods in preventing sexually transmitted infections and HIV: current evidence and future research directions. Sex Transm Infect 81(3):193–200

    PubMed  CAS  Google Scholar 

  85. Vijayakumar G, Mabude Z, Smit J, Beksinska M, Lurie M (2006) A review of female-condom effectiveness: patterns of use and impact on protected sex acts and STI incidence. Int J STD AIDS 17(10):652–659

    PubMed  Google Scholar 

  86. Pinter B (2002) Continuation and compliance of contraceptive use. Eur J Contracept Reprod Health Care 7(3):178–183

    PubMed  CAS  Google Scholar 

  87. Raymond E, Dominik R (1999) Contraceptive effectiveness of two spermicides: a randomized trial. Obstet Gynecol 93(6):896–903

    PubMed  CAS  Google Scholar 

  88. Fu H, Darroch JE, Haas T, Ranjit N (1999) Contraceptive failure rates: new estimates from the 1995 National Survey of Family Growth. Fam Plann Perspect 31(2):56–63

    PubMed  CAS  Google Scholar 

  89. Schwartz JL, Mauck C, Lai JJ, Creinin MD, Brache V, Ballagh SA, Weiner DH, Hillier SL, Fichorova RN, Callahan M (2006) Fourteen-day safety and acceptability study of 6% cellulose sulfate gel: a randomized double-blind Phase I safety study. Contraception 74(2):133–140

    PubMed  CAS  Google Scholar 

  90. Ballagh SA, Brache V, Mauck C, Callahan MM, Cochon L, Wheeless A, Moench TR (2008) A Phase I study of the functional performance, safety and acceptability of the BufferGel Duet. Contraception 77(2):130–137

    PubMed  CAS  Google Scholar 

  91. Barnhart KT, Rosenberg MJ, MacKay HT, Blithe DL, Higgins J, Walsh T, Wan L, Thomas M, Creinin MD, Westhoff C et al (2007) Contraceptive efficacy of a novel spermicidal microbicide used with a diaphragm: a randomized controlled trial. Obstet Gynecol 110(3):577–586

    PubMed  Google Scholar 

  92. Centers for Disease Control and Prevention (1988) Condoms for prevention of sexually transmitted diseases. MMWR Morb Mortal Wkly Rep 37(9):133–137

    Google Scholar 

  93. Moreau C, Trussell J, Rodriguez G, Bajos N, Bouyer J (2007) Contraceptive failure rates in France: results from a population-based survey. Hum Reprod 22(9):2422–2427

    PubMed  CAS  Google Scholar 

  94. Trussell J (2004) Contraceptive efficacy. In: Hatcher RA et al (eds) Contraceptive technology, 18th revised edn. Ardent Media, New York.

    Google Scholar 

  95. Gallo MF, Grimes DA, Lopez LM, Schulz KF (2006) Non-latex versus latex male condoms for contraception. Cochrane Database Syst Rev (1):CD003550

    Google Scholar 

  96. Hales BF, Smith S, Robaire B (1986) Cyclophosphamide in the seminal fluid of treated males: transmission to females by mating and effect on pregnancy outcome. Toxicol Appl Pharmacol 84(3):423–430

    PubMed  CAS  Google Scholar 

  97. Paladine WJ, Cunningham TJ, Donavan MA, Dumper CW (1975) Letter: Possible sensitivity to vinblastine in prostatic or seminal fluid. N Engl J Med 292(1):52

    PubMed  CAS  Google Scholar 

  98. Kahn JA (2001) An update on human papillomavirus infection and Papanicolaou smears in adolescents. Curr Opin Pediatr 13(4):303–309

    PubMed  CAS  Google Scholar 

  99. Winer RL, Hughes JP, Feng Q, O’Reilly S, Kiviat NB, Koutsky LA (2009) Comparison of incident cervical and vulvar/vaginal human papillomavirus infections in newly sexually active young women. J Infect Dis 199(6):815–818

    PubMed  Google Scholar 

  100. Castle PE, Schiffman M, Herrero R, Hildesheim A, Rodriguez AC, Bratti MC, Sherman ME, Wacholder S, Tarone R, Burk RD (2005) A prospective study of age trends in cervical human papillomavirus acquisition and persistence in Guanacaste, Costa Rica. J Infect Dis 191(11):1808–1816

    PubMed  Google Scholar 

  101. Moscicki AB (1999) Human papillomavirus infection in adolescents. Pediatr Clin North Am 46(4):783–807

    PubMed  CAS  Google Scholar 

  102. Woodman CB, Collins S, Winter H, Bailey A, Ellis J, Prior P, Yates M, Rollason TP, Young LS (2001) Natural history of cervical human papillomavirus infection in young women: a longitudinal cohort study. Lancet 357(9271):1831–1836

    PubMed  CAS  Google Scholar 

  103. Malouf MA, Hopkins PM, Singleton L, Chhajed PN, Plit ML, Glanville AR (2004) Sexual health issues after lung transplantation: importance of cervical screening. J Heart Lung Transplant 23(7):894–897

    PubMed  Google Scholar 

  104. Rose B, Wilkins D, Li W, Tran N, Thompson C, Cossart Y, McGeechan K, O’Brien C, Eris J (2006) Human papillomavirus in the oral cavity of patients with and without renal transplantation. Transplantation 82(4):570–573

    PubMed  Google Scholar 

  105. Courtney AE, Leonard N, O’Neill CJ, McNamee PT, Maxwell AP (2009) The uptake of cervical cancer screening by renal transplant recipients. Nephrol Dial Transplant 24(2):647–652

    PubMed  Google Scholar 

  106. Bouwes Bavinck JN, Berkhout RJ (1997) HPV infections and immunosuppression. Clin Dermatol 15(3):427–437

    PubMed  CAS  Google Scholar 

  107. Volkow P, Rubi S, Lizano M, Carrillo A, Vilar-Compte D, Garcia-Carranca A, Sotelo R, Garcia B, Sierra-Madero J, Mohar A (2001) High prevalence of oncogenic human papillomavirus in the genital tract of women with human immunodeficiency virus. Gynecol Oncol 82(1):27–31

    PubMed  CAS  Google Scholar 

  108. Sun XW, Kuhn L, Ellerbrock TV, Chiasson MA, Bush TJ, Wright TC Jr (1997) Human papillomavirus infection in women infected with the human immunodeficiency virus. N Engl J Med 337(19):1343–1349

    PubMed  CAS  Google Scholar 

  109. Bunin N, DiDomenico C, Guzikowski V (2005) Hematopoietic stem cell transplantation. In: Schwartz CL, Hobbie WL, Constine LS, Ruccione KS (eds) Survivors of childhood and adolescent cancer. Springer, Berlin, Heidelberg, pp 271–282

    Google Scholar 

  110. Sasadeusz J, Kelly H, Szer J, Schwarer AP, Mitchell H, Grigg A (2001) Abnormal cervical cytology in bone marrow transplant recipients. Bone Marrow Transplant 28(4):393–397

    PubMed  CAS  Google Scholar 

  111. Fujimura M, Ostrow RS, Okagaki T (1991) Implication of human papillomavirus in postirradiation dysplasia. Cancer 68(10):2181–2185

    PubMed  CAS  Google Scholar 

  112. Barzon L, Pizzighella S, Corti L, Mengoli C, Palu G (2002) Vaginal dysplastic lesions in women with hysterectomy and receiving radiotherapy are linked to high-risk human papillomavirus. J Med Virol 67(3):401–405

    PubMed  Google Scholar 

  113. Ault KA (2007) Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials. Lancet 369(9576):1861–1868

    PubMed  Google Scholar 

  114. Paavonen J, Jenkins D, Bosch FX, Naud P, Salmeron J, Wheeler CM, Chow SN, Apter DL, Kitchener HC, Castellsague X et al (2007) Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial. Lancet 369(9580):2161–2170

    PubMed  CAS  Google Scholar 

  115. Centers for Disease and Control Prevention (2009) National, state, and local area vaccination coverage among adolescents aged 13–17 years— United States. MMWR Morb Mortal Wkly Rep 59(32):1018–1023

    Google Scholar 

  116. Klosky JL, Gamble HL, Spunt SL, Randolph ME, Green DM, Hudson MM (2009) Human papillomavirus vaccination in survivors of childhood cancer. Cancer 115(24):5627–5636

    PubMed  Google Scholar 

  117. Winer RL, Hughes JP, Feng Q, O’Reilly S, Kiviat NB, Holmes KK, Koutsky LA (2006) Condom use and the risk of genital human papillomavirus infection in young women. N Engl J Med 354(25):2645–2654

    PubMed  CAS  Google Scholar 

  118. Killick S (ed) (2000) Contraception in practice. Martin Dunitz Ltd, London, pp 19–28

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Valerie Laurence MD .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer Science+Business Media B.V.

About this chapter

Cite this chapter

Laurence, V., Rousset-Jablonski, C. (2012). Contraception and Cancer Treatment in Young Persons. In: Quinn, G., Vadaparampil, S. (eds) Reproductive Health and Cancer in Adolescents and Young Adults. Advances in Experimental Medicine and Biology, vol 732. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-2492-1_4

Download citation

Publish with us

Policies and ethics