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Application of Geostatistics in Cancer Studies

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Part of the book series: Quantitative Geology and Geostatistics ((QGAG,volume 16))

Abstract

This paper presents an overview of geostatistical methods available for the analysis of both areal and individual-level health data. The application of Poisson kriging and p-field simulation to lung cancer mortality rates recorded for white males in 688 US counties of the Southeast (1970–1994) allowed: (1) the creation of noise-filtered mortality maps at the county-level and over a fine grid (isopleth maps), (2) the detection of clusters of low or high mortality counties that are significantly correlated in space, and (3) the identification of areas where the local correlation of mortality rates is stronger for white males than for white females, revealing gender-specific factors such as occupational exposure. Then, indicator kriging is introduced as a way to map the risk for late stage breast cancer diagnosis using patient residences across Michigan.

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References

  • Ali M, Goovaerts P, Nazia N, Haq MZ, Yunus M, Emch M (2006) Application of Poisson kriging to the mapping of cholera and dysentery incidence in an endemic area of Bangladesh. Int J Health Geogr 5:45

    Article  Google Scholar 

  • Anselin L (1995) Local indicators of spatial association – LISA. Geogr Anal 27:93–115

    Article  Google Scholar 

  • Besag J, York J, Mollie A (1991) Bayesian image restoration with two applications in spatial statistics. Ann Inst Stat Math 43:1–59

    Article  Google Scholar 

  • Castro MC, Singer BH (2006) Controlling the false discovery rate: a new application to account for multiple and dependent tests in local statistics of spatial association. Geogr Anal 38:180–208

    Article  Google Scholar 

  • Devesa SS, Grauman DJ, Blot WJ, Fraumeni JF Jr (1999) Cancer surveillance series: changing geographic patterns of lung cancer mortality in the United States, 1950 through 1994. J Natl Canc Inst 91(12):1040–1050

    Article  Google Scholar 

  • Goovaerts P (2005a) Detection of spatial clusters and outliers in cancer rates using geostatistical filters and spatial neutral models. In: Renard Ph, Demougeot-Renard H, Froidevaux R (eds) geoENV V – geostatistics for environmental applications. Springer, Berlin/Germany, pp 149–160

    Chapter  Google Scholar 

  • Goovaerts P (2005b) Geostatistical analysis of disease data: estimation of cancer mortality risk from empirical frequencies using Poisson kriging. Int J Health Geogr 4:31

    Article  Google Scholar 

  • Goovaerts P (2006a) Geostatistical analysis of disease data: visualization and propagation of spatial uncertainty in cancer mortality risk using Poisson kriging and p-field simulation. Int J Health Geogr 5:7

    Article  Google Scholar 

  • Goovaerts P (2006b) Geostatistical analysis of disease data: accounting for spatial support and population density in the isopleth mapping of cancer mortality risk using area-to-point Poisson kriging. Int J Health Geogr 5:52

    Article  Google Scholar 

  • Goovaerts P (2008a) Accounting for rate instability and spatial patterns in the boundary analysis of cancer mortality maps. Environ Ecol Stat 4:421–446

    Article  Google Scholar 

  • Goovaerts P (2008b) Kriging and semivariogram deconvolution in presence of irregular geographical units. Math Geosci 40:101–128

    Article  Google Scholar 

  • Goovaerts P, Gebreab S (2008) How does Poisson kriging compare to the popular BYM model for mapping disease risks? Int J Health Geogr 7:6

    Article  Google Scholar 

  • Goovaerts, P. 2009. Medical geography: a promising field of application for geostatistics. Math. Geosci 41(3):243–264

    Article  Google Scholar 

  • Goovaerts P, Jacquez GM (2004) Accounting for regional background and population size in the detection of spatial clusters and outliers using geostatistical filtering and spatial neutral models: the case of lung cancer in Long Island, New York. Int J Health Geogr 3:14

    Article  Google Scholar 

  • Goovaerts P, Jacquez GM (2005) Detection of temporal changes in the spatial distribution of cancer rates using LISA statistics and geostatistically simulated spatial neutral models. J Geogr Syst 7:137–159

    Article  Google Scholar 

  • Jacquez GM, Meliker JR, AvRuskin G, Goovaerts P, Kaufmann A, Wilson ML, Nriagu J (2006) Case-control geographic clustering for residential histories accounting for risk factors and covariates. Int J Health Geogr 5:32

    Article  Google Scholar 

  • James L, Matthews I, Nix B (2004) Spatial contouring of risk: a tool for environmental epidemiology. Epidemiology 15:287–292

    Article  Google Scholar 

  • Kelsall J, Wakefield J (2002) Modeling spatial variation in disease risk: a geostatistical approach. J Am Stat Assoc 97(459):692–701

    Article  Google Scholar 

  • Lajaunie C (1991) Local risk estimation for a rare noncontagious disease based on observed frequencies. Note N-36/91/G. Centre de Géostatistique, Ecole des Mines de Paris

    Google Scholar 

  • Monestiez P, Dubroca L, Bonnin E, Durbec JP, Guinet C (2006) Geostatistical modelling of spatial distribution of Balenoptera physalus in the Northwestern Mediterranean Sea from sparse count data and heterogeneous observation efforts. Ecol Model 193:615–628

    Article  Google Scholar 

  • Richardson S, Thomson A, Best N, Elliot P (2004) Interpreting posterior relative risk estimates in disease-mapping studies. Environ Health Perspect 112:1016–1025

    Article  Google Scholar 

  • Webster R, Oliver MA, Muir KR, Mann JR (1994) Kriging the local risk of a rare disease from a register of diagnoses. Geogr Anal 26:168–185

    Article  Google Scholar 

  • Woodward P (2005) BugsXLA: Bayes for the common man. J Stat Softw 14:5

    Google Scholar 

Download references

Acknowledgments

This research was funded by grant R44-CA132347-01 from the National Cancer Institute. The views stated in this publication are those of the author and do not necessarily represent the official views of the NCI.

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Correspondence to Pierre Goovaerts .

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Goovaerts, P. (2010). Application of Geostatistics in Cancer Studies. In: Atkinson, P., Lloyd, C. (eds) geoENV VII – Geostatistics for Environmental Applications. Quantitative Geology and Geostatistics, vol 16. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-2322-3_10

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