Skip to main content

Part of the book series: Topics in Anaesthesia and Critical Care ((TIACC))

Abstract

The gut seems to play a major role in the development of systemic infection and multiple organ failure in critically ill patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Sganga G., Gangeri G., Castagneto M (1998) The gut: a central organ in the development of multiple organ system failure. In: van Saene HKF, Silvestri L, de la Cal MA (eds) Infection control in the intensive care unit. Springer-Verlag, Milan, pp 257–268.

    Google Scholar 

  2. Baker JW, Deitch EA, Li M et al (1988) Hemorrhagic shock induces bacterial translocation from the gut. J Trauma 28:896.

    Article  PubMed  CAS  Google Scholar 

  3. Deich EA, Specian RD, Berg RD (1991) Endotoxin induced bacterial translocation and mucosal permeability: role of xantine oxidase complement activation and macrophage products. Crit Care Med 19:178.

    Google Scholar 

  4. Fukushima R, Gianotti L, Alexander JW et al (1992) The degree of bacterial translocation is a determinant factor for mortality after burn injury and is improved by prostaglandin analogs. Ann Surg 216:438.

    Article  PubMed  CAS  Google Scholar 

  5. Jonnes WG II, Barber AE, Minei JP, Fathey TJ III, Shires GT III, Shires GT (1991) Differential pathophysiology of bacterial translocation after thermal injury and sepsis. Ann Surg 214(1):24–31.

    Article  Google Scholar 

  6. Berg RD (1975) Translocation of certain indigenous bacteria from the gastrointestinal tract to the mesenteric lymph nodes and other organs in a grotobiotic mouse model. Infect Immun 23:403.

    Google Scholar 

  7. Morales J, Kibsey P, Thomas PD et al (1992) The effects of ischemia and ischemia reperfusion, lipid peroxidation and gut histology: studies on hemorrhagic shock in pigs. J Trauma 33:221.

    Article  PubMed  CAS  Google Scholar 

  8. Jones WF II, Minei JP et al (1990) Bacterial translocation and intestinal atrophy after thermal injury and burn wound sepsis. Ann Surg 211:399.

    Article  PubMed  Google Scholar 

  9. Berg RD (1986) Bacterial translocation from the gastrointestinal tract-immunologic aspects. Microecol Ther 16:131.

    Google Scholar 

  10. Goris R (1988) MOF: whole body inflammation caused by angry leucocytes and mad macrophages. APICE, Trieste, p 191.

    Google Scholar 

  11. Deich EA, Kemper AC, Specian RD et al (1992) A study of the relationship among survival, gut origin sepsis, and bacterial translocation in a model of systemic inflammation. J Trauma 32:141.

    Google Scholar 

  12. Epstein MD, Banducci DR, Manders EK (1992) The role of the gastrointestinal tract in the development of burn sepsis. Plast Reconstr Surg 90(3):524–531.

    Article  PubMed  CAS  Google Scholar 

  13. Marshall JC, Christou NV, Meakins JL (1993) The gastrointestinal tract: the “undrained abscess” of multiple organ failure. Ann Surg 218:111–119.

    Article  PubMed  CAS  Google Scholar 

  14. Gullo A, Berlot G, Silvestri L, Sganga G (1992) Sepsis and Organ Failure. Systems Editore, pp 1–235.

    Google Scholar 

  15. Sganga G, Gangeri G, Montemagno S, Castagneto M (1994) Prevention of translocation, prevention of MOFS? In: Mutz NJ, Koller W, Benzer H (eds) Proceedings of the 7th European Congress of Intensive Care Medicine. Monduzzi, Bologna, pp 93–101.

    Google Scholar 

  16. Madara JL (1990) Pathobiology of the intestinal epithelial barrier. Am J Pathol 137:1273.

    PubMed  CAS  Google Scholar 

  17. Baue AE (1993) The role of the gut in the development of multiple organ dysfunction in cardiothoracic patients. Ann Thorac Surg 55:822–829.

    Article  PubMed  CAS  Google Scholar 

  18. Moore FA, Moore EE, Poggetti R, McAnena, Peterson VM, Abernathy CM, Parsons PE (1991) Gut bacterial translocation via the portal vein: a clinical perspective with major torso trauma. J Trauma 31(5):629–636.

    Article  PubMed  CAS  Google Scholar 

  19. Peitzman AB, Udekwu AO, Ochoa J, Smith S (1991) Bacterial translocation in trauma patients. J Trauma 31(8): 1083–1086.

    PubMed  CAS  Google Scholar 

  20. Brathwaite CEM, Ross SE, Nagele R et al (1993) Bacterial translocation occurs in humans after traumatic injury: evidence using immunofluorescence. J Trauma 34: 586–590.

    Article  PubMed  CAS  Google Scholar 

  21. Daly JM, Lieberman MD et al (1992) Enterai nutrition with supplemental arginine, RNA and ω-3 fatty acids in patients after operation: immunologic, metabolic, and clinical outcome. Surgery 112:56.

    PubMed  CAS  Google Scholar 

  22. Gianotti L, Braga M, Vignali A, Gentilini O, Fortis C, Soldini L, Di Carlo V (1997) Nutrizione perioperatoria con una miscela enterale arricchita in arginina, acidi grassi co-3 ed RNA. Effetti metabolici e nutrizionali. Riv Ital Nutr Parentera Enterai 15(3):219.

    Google Scholar 

  23. van Saene HKF, Stoutenbeek CP, Stoller JK (1992) Selective decontamination of the digestive tract in the intensive care unit: current status and future prospects. Critical Care Medicine 20:691–703.

    Article  PubMed  Google Scholar 

  24. Sganga G, Gangeri G, De Gaetano A, Castagneto M (1992) Metabolic derangments and VO2/DO2 unbalance in sepsis and organ failure. In: Gullo A, Berlot G, Silvestri L, Sganga G (eds) Sepsis and organ failure. Systems, pp 75-89.

    Google Scholar 

  25. Deich EA, Taylor M, Grisham MB et al (1994) Endotoxin induces bacterial translocation and increases xanthine oxidase activity. J Trauma 29:1679–1989.

    Article  Google Scholar 

  26. Sganga G, Gangeri G, Gui D, Castagneto M (1997) Oxidative stress and antioxidants in clinical sepsis. Intensive Care Med 20(Suppl 1):127.

    Google Scholar 

  27. Siegemund M, Studer W, Ince C (1998) Ischemia/reperfusion of the gut. In Vincent JL (ed) Yearbook of intensive care and emergency medicine. Springer-Verlag, Berlin Heidelberg New York, pp 637–648.

    Google Scholar 

  28. Hyuang KF, Chung DH, Herndon DN (1993) Insulin-like growth factor reduces gut atrophy and bacterial translocation after severe burn injury. Arch Surg 128:47.

    Article  Google Scholar 

  29. Gianotti L, Alexander W, Jukushima R, Pyles T (1993) Reduction of bacterial translocation with oral fibroblast growth factor and sucralfate. Am J Surg 165:195.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1999 Springer-Verlag Italia, Milano

About this chapter

Cite this chapter

Sganga, G., Castagneto, M. (1999). Bacterial translocation. In: Guarnieri, G., Iscra, F. (eds) Metabolism and Artificial Nutrition in the Critically Ill. Topics in Anaesthesia and Critical Care. Springer, Milano. https://doi.org/10.1007/978-88-470-2901-9_20

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-2901-9_20

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0042-1

  • Online ISBN: 978-88-470-2901-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics