Abstract
There are currently two types of bone regeneration, physiological and reparative. Many authors consider reparative regeneration as occurring only in case of traumatic or other type of pathogenic injury of bone [106–110]. The basis for reparative regeneration is cell division [111]. If following injury, the differentiated structures are substituted by a dense fibrous connective tissue scar, the process is referred to as substitution [110, 111].
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References
Voitkevich AA, Krasnoschekov GP (1971) Some aspects on modern posttraumatic regeneration. Archiv anatomii 3:92–106
Lavrischeva GI, Onoprienko GA (1996) Morphologic and clinical aspects of reparative regeneration of limbs and tissues. Meditsina, Moscow
Mjadelets OD (2002) Main principles of cytology, embryology and general gystology. NGMA, N. Novgorod
Avrunin AS, Kornilov NV et al (2001) Restructuring of mineral matrix of bone tissue. Morfologia 2:37–40
Kchussar PU et al (2001) Posttraumatic tibial reparation on rats. Morfologia vol 120(5):84–91
Jarigin NE, Serov VV (1977) Atlas of pathological histology. Meditsina, Moscow
Belous AM, Pankov EY (1972) Bone tissue regeneration mechanisms. Meditsina, Moscow
Mikchailova LN (1988) Reparative regeneration of bone and cartilage tissue under influence of different biomechanical factors. MD dissertation, Moscow, p 29
Vinogradova TP, Lavrischeva GI (1974) Bone regeneration and grafting. Meditsina, Moscow
Kamalov II (1976) Regeneration in skull injuries and defects. In: Reparative regeneration and its regulation, vol XX. Leningrad, pp 101–107
Shevtsov VI, Irjianov UM (1999) Ultrastructural features of ontogenesis in fracture fusion. Genij ortopedii 4:13–18
Ozaki A et al (2000)
Gololobov VG, Deev RV (2003) Stromal cells and osteoblastic cell differon. Morfologia 123(1):9–19
Korzh AA, Belous AM, Pankov EA (1972) Reparative bone regeneration. Moscow
Axhausen W (1956) Osteogenic phases of regeneration of bone; historical and experimental study. J Bone Joint Surg 38-A:593–600
Tevosjan GV (1979) Bone marrow in bone formation and its reparative potentiality in fracture healing. PhD thesis, Erevan
Frindstein AY, Lalikina KS (1973) Bone tissue induction and osteogenous cells. Meditsina, Moscow
Bruder et al (1994)
Nogemi et al (1984)
Danilov PK et al (2000) Histological principles of limb tissue regeneration. Ortopedia i travmatologia 2:102
Ulumbekov EG et al (1998) Histology (introduction to pathology). GOETAR-MED, Moscow
Rodionova NV (1989) Functional cellular morphology in osteogenesis. Naukova dumka, Kiev
Caplan (1987)
Baroukh et al (2000)
Gololobov VG (2004) Posttraumatic bone tissue regeneration. In: Fundamental and applied problems, vol 257. VMA, St. Petersburg, pp 94–109
Rusakov AV (1959) Pathological anatomy of bone diseases. An introduction into physiology and pathology of bone tissue. Nauka, Moscow
Stetsula VI (1993) System knowledge of real complexity of fracture healing. Ortopedia i travmotologia 2:57–61
Sukchanov AV, Avrunin AC, Kornilov NV (1997) Bone tissue restructuring after bone damage. Morfologia 112:82–87
Miller SC, De Saint-Georges L, Bowman BM, Jee WS (1989) Bone lining cells: structure and function. Scanning Microsc 3:953–960; discussion 960–961
Kruglikov GG et al (1977) Fibroplasts differentiation in collagen formation. Ontogenesis 8:186–190
Samusev RP, Pupisheva GI, Smirnov AV (2004) Atlas of cytology, histology and embryology. ONICS 21, Moscow
Jurina et al (1990)
Popsujshapka (1992)
Ham A, Cormac D (1983) Histology. Mir, Moscow
Shimizu et al (1989) Chapter 8
Delloye et al (1990)
Ilizarov GA, Shreiner AA, Imerlishvili IA (1986) Osteogenous potentiality of bone marrow diaphysis. In: Proceedings of international conference on transosseous osteosynthesis. RSC “RTO”, Kurgan, 1986, pp 28–28
Golovin (1961)
Ilizarov GA (1975) External fixation using the author’s device in acute trauma. In: Third all-union congress of traumatologists and orthopedists, Moscow, 1975, pp 148–153
Shreiner (1990) Chapter 8 (in reference group 143–147)
Barabash AP, Solomin LN (1997) “Esperanto” of transosseous elements insertion in osteosynthesis by Ilizarov device. Nauka, Novosibirsk
Solomin et al (2003)
Ilizarov GA, Imershvili IA, Bachlikov UN (1982) Reparative bone formation in distraction osteosynthesis by Ilizarov. In: Problems of transosseous osteosynthesis in orthopedics and traumotology, RSC “RTO”, Kurgan, 1982, vol 8, pp 27–33
Ilizarov GA, Ledjaev V I, Imerlishvili I A (1972) Some facts from morphologic studying of bone formation in case of distraction osteosynthesis. In: Transosseous compression and distraction osteosynthesis in traumotology and orthopaedics. RSC “RTO”, Kurgan, 1972, vol 2, pp 217–237
Ilizarov et al (1999)
Ilizarov GA (1984) Importance of optimum mechanical and biological factors in trasosseous osteosynthesis regeneration. In: Proceedings of international symposium on transosseous osteosynthesis. RSC “RTO”, Kurgan, 1984, pp 8–49
Iljina VK, Meerson EM (1998) Cellular and genetic parameters of reparative osteosynthesis. Ontogenesis 29(6):471
Kataev IA, Lobko AJa, Chernish VU (1996) Limb lengthening. In: Proceedings of V republican conference of crimean traumotologists, Yalta, 1996, pp 46–47
Shevtsov VI, Popkov AV, Burlakov EV (2000) Sheboop distracter. Genij ortopedii 1:93–95
Bliskunov AI (1983) Lengthening of hip by guided implants. Moscow
Golubev GSh (1998) Ilizarov device computer navigation. Dissertation, Moscow
Ilizarov GA et al (1988) Drive to compression-distraction device. Patent 1423114, Bulletin 34
Pursley JA, Holloway JM, Wakefield TL (1990) Automatic compression-distraction-torsion method and apparatus. US Patent 4,973,331
Paley D et al (1990) Problems, obstacles, and complications of limb lengthening by the Ilizarov technique. Clin Orthop 250:81–104
Lass et al (1996)
Popkov AV, Saldin VV, Novikov KI, Schukin AA (1998) Rehabilitation of short people (methodological recommendations). RSC “RTO,” Kurgan, 1998
Chirkova AM, Erofeev CA (1997) Reparative regeneration and bone restructuring after braking distraction regenerate. Genij ortopedii 4:39–42
Stetsula VI, Devjatov AA (1987) Transosseous osteosynthesis in traumotology. Zdorovje, Kiev
Shevtsov (1997)
Popkov AV, Erofeev SA, Popkov DA (2000) Bone formation X-ray examination dynamics in compression-distraction osteosynthesis. Genij ortopedii 3:5–9
Devjatov AA, Kaplunov AG (1978) Complications in Ilizarov device external fixation. Compression and distraction transosseous osteosyntesis 4:84–92
Kochutina LN (1992) Muscle and tendon limb regeneration in lengthening with aid of mono and bilocal distraction osteosynthesis by Ilizarov. MD dissertation, St. Petersburg
Aranovich AM et al (2002) Contracture of knee joint at lengthening of lower leg in achondroplasia. Genius Orthop 3:58–60
Reutov AI (2002) Comparative characteristics of mono and bilocal distraction osteosynthesis by Ilizarov. Ginij ortopedii 3:108–105
De Deyne (2002)
Green et al (2002)
Osepjan IA et al (1988) Autotransplantation of bone tissue fibroblasts in grammatology and orthopedics. Vestnik kchirurgii 5:70–71
Prokopova LV, Nikolaeva NG (1990) Use of UV-irradiated autological bone marrow at treating bone defects in children. Ortopedia i travmotologia 9:25–28
Sirij OM (1987) Bone marrow autografting in bone tissue damage. PhD thesis, Moscow
Shevtsov VI, Shved SI, Sisenko JM (2002) Transosseous osteosynthesis in treatment of comminuted fractures. ZAO Dammi, Kurgan
Shevtsov VI et al (2003) Distraction regenerate osteogenesis stimulation using bone marrow. Genij ortopedii 3:131–138
Desyatchenko KS et al (1989) Influence of protein growth control factors of out cell bone tissue matrix on reparative osteogenesis and blood supply. Tsitologia 31(9):92
Grebneva (1998)
Kovinka MA (2002) Bone regeneration regulation in achondroplasia. PhD dissertation, Tumen
Desyatchenko KS et al. (1997) Influence of bone growth factors on distraction regenerate. Bull Exp Biol Med 8:233–236.
Desyatcheko KS et al (2002) Methods of reparative osteogenesis stimulation. Patent 2193868 of Russian Federation. Bulletin 34
Teot (1987)
Lascombes (2001)
Prévot et al (1993)
Shevtsov et al (2004)
Bliskunov AI et al (1996) Various osteotomies in lengthening of hip by Bliskunov device. Vestnik travmatologii i ortopedii 3:22–30
Guichet JM et al (2003) Gradual femoral lengthening with the albizzia intramedullary nail. J Bone Joint Surg 85:838–848
Paley D et al (1994) Deformity planning for frontal and sagittal plane corrective osteotomies. Orthop Clin North Am 25:425–465
Кojimoto et al (1991)
Paley et al (1993)
Kocaoglu M et al (2004) Complications encountered during lengthening over an intramedullary nail. J Bone Joint Surg 86-A:2406–2411
Paley D, Herzenberg JE, Paremain G, Bhave A (1997) Femoral lengthening over an intramedullary nail. A matched-case comparison with Ilizarov femoral lengthening. J Bone Joint Surg 79-A(10):1464–1480
Huang et al (1998)
Baumgart et al (1996)
Lee et al (1997)
Yamamoto et al (1998)
Simpson AH, Cole AS, Kenwright J (1999) Leg lengthening over an intramedullary nail. J Bone Joint Surg 81-B:1041–1045
Shepherd et al (2001)
Gordon JE et al (2002) Femoral lengthening over a humeral intramedullary nail in preadolescent children. J Bone Joint Surg 84-A:930–937
Kreitz et al (2000)
Kristiansen et al (1999)
Lin et al (1996)
Caton et al (2001)
Vinogradova TP, Lavrischeva GI (1974) Bone regeneration and grafting. Meditsina, Moscow
Shevtsov VI, Makushin BD, Pozharishchensky KE (1994) The treatment of patients with tibial defects by the method of reconstructive tibialization of the fibula. Periodika, Kurgan
Larionov et al (1999)
Larionov et al (2004)
Omeljanenko NP, Slutski LI (2009) Connective tissue (histology and biochemistry). Izvestija, Moscow
Razumovsky (1983)
Nikitin et al (2001)
Rodenburg (1974)
Lotzeva et al (1974)
Lotzeva (1980)
Tkachenko and Rutzkij (1987)
Boltrukevitch (1989)
Vyaljko (1997)
Grischenko (2000)
Kalatcheva (2004)
Lekishvili (2002)
von Verzen (1993)
Saveljev and Sivkov (1986)
Urist MR, Strates BS (1970) Bone formation in implants of partially and wholly demineralized bone matrix: including observations on acetone-fixed intra and extracellular proteins. Clin Orthop Relat Res 71:271–278
Aspenberg P, Wittbjer J, Thorngren KG (1986) Pulverized bone matrix as an injectable bone graft in rabbit radius defects. Clin Orthop Relat Res 206:261–268
Russell JL, Block JE (1999) Clinical utility of demineralized bone matrix for osseous defects, arthrodesis, and reconstruction: impact of processing techniques and study methodology. Orthopedics 22:524–531
Omeljanenko and Buturin (1994)
Omelyanenko et al (1996)
Omelyanenko (2002)
Malakhov et al (2003)
Lekishvili (2004)
Barabash (2001)
Guljnazarova et al (2001)
Snetkov et al (2002)
Kesjan et al (2003)
Krasnov et al (2004)
Pitkevitch et al (2004)
Lavrikova (2004)
Boden (1999)
Barkov (2000)
Samodaj et al (2005)
Lane et al (1999)
Lavrikova and Sumarokov (2004)
Krasnov (2005)
Krasnoyarov and Stemplevskij (2004)
Kanukin et al (1999)
Malakhov et al (2004)
Urist et al (2001)
Termaat et al (2005)
Chekanov AV et al (2010) Making new osteoinductive materials on the basis of recombinative morphologic genetic VMR proteins for bone tissue regeneration. In: Proceedings of IV Russian symposium on tissue and cellular transplantology, St. Petersburg, 2010, pp 199–200
Lietman et al (2005)
Kochetkov US (2002) Biological and surgical aspects of osteogenesis stimulation. MD dissertation, Kurgan
Kirillova et al (2008)
Nikolaienko NS et al (2009) Problems of standardization, cultivation and differentiation of stroma cells of bone marrow in humans and animals. In: Autologous cells: experiments and application. Litterra, Moscow, pp 42–57
Bruder et al (1998)
Mironov SP (2007) Biomedical technologies of reparative osteogenesis control. In: Proceedings of III Russian symposium on tissue and cellular transplantology, Moscow, 2007, pp 27–28
Krugljakov PV, Sokolova IB (2005) Influence of singenic complexes on bone tissue regeneration in grafting of demineralised bone matrix. Tsitoligia 47:466–476
Malginov NN, Frolov EN (2007) Reparative regeneration of rat’s bones at inserting titan implants with xenogeny mesenchimal stem cells. In: Proceedings of III Russian symposium on tissue and cellular transplantology, Moscow, 2007, pp 83–84
Krasheninnikov et al (2010)
Maljginov et al (2007)
Shevtsov VI et al (2004) Experimental adaptive distraction osteogenesis stimulation by means of automiel transplantation. In: Proceedings of international conference on limb function, Kurgan, 2004, pp 345–347
Erofeev SA, Osipova EV, Emanov AA (2010) Influence of cultivated fetal fibroplasts on bone regenerate mineralization in case of transosseous distraction osteogenesis. Actual issues of tissue and cell transplantology. Theses of symposium, St. Petersburg, 2010, pp 254–255
Fridenshtein (1986)
Goel et al (2005)
Belousov VD, Chobanu AA, Chobanu FI (1990) Conservative treatment of long bone non-unions. STIINTSA, Kishinev
Osepjan IA et al (1987) Treatment of malunions, non-unions and defects of long bones using grafting of fibroblasts grown in vitro and impregnated in sponge bone matrix. Ortopedia i travmatologia 9:59–61
Savintsev AM, Smoljaninov AB, Malko AV (2010) Stroma stem cells in surgery of neck of femur. In: Proceedings of IV Russian symposium on tissue and cellular transplantology, St. Petersburg, 2010, pp 286–287
Onischenko et al (2009)
Sizikov MU et al (2006) Therapy of posttraumatic limb bone pseudoarthroses by means of autologous stroma stem cells osteoinduction. In: Proceedings of the annual international conference on stem cells, Moscow, 2006, pp 95–97
Schepkina EA (2010) Grafting of autogenous maltipotent mesenchimal stroma cells on deminerilized bone matrix in treatment of long bone non-unions. Kletochnaja transplantologia I tkanevaja injeniria 2:67–74
Osepjan IA et al (1987) Treatment of malunions, non-unions and defects of long bones using grafting of fibroblasts grown in vitro and impregnated in sponge bone matrix. Ortopedia i travmatologia 9:59–61
Schepkina EA, Krugljakov PV et al (2007) Grafting of autologous mesenchimal stem cells on deminerilized bone matrix in non-unions and bone defects plastics. In: Actual issues of cellular and tissue transplantology. CITO, Moscow, p 113
Bistrov AV, Shumakov IV et al (2009) Use of bone marrow cells immobilized on matrix. LAVR, Moscow
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Erofeev, S.A., Shchepkina, E.A. (2012). Features of Reparative Osteogenesis and the Management of Distraction Osteogenesis in External Fixation. In: Solomin, L. (eds) The Basic Principles of External Skeletal Fixation Using the Ilizarov and Other Devices. Springer, Milano. https://doi.org/10.1007/978-88-470-2619-3_8
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