Skip to main content
SpringerLink
Log in

Multiple Pregnancies

  • Chapter
Neonatology

  • 500 Accesses

Abstract

The cultural modifications in women’s reproductive strategies over the past 50 years have drastically influenced the demographic scenario. Higher levels of education and a desire for economic and social success, as well as difficulties in finding a permanent job, have played a major role in modifying the reproductive strategies, as evidenced by delayed parenthood and the reduction in family size [1]. In addition to this expected twinning rate due to advancing maternal age, there is also evidence that natural twinning has increased in women who have been exposed to assisted reproduction technologies [2].

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 149.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Astolfi P, Ulizzi L, Zonta LA (2003) Changes in twinning rate: Italy 1950–1996. Hum Reprod 18:207–211

    Article  PubMed  CAS  Google Scholar 

  2. Bortolus R, Parazzini F, Chatenoud L et al (1999) The epidemiology of multiple births. Hum Reprod Update 5:179–187

    Article  PubMed  CAS  Google Scholar 

  3. ESHRE Capri Workshop Group (2000) Multiple gestation pregnancy. Hum Reprod 15:1856–1864

    Article  Google Scholar 

  4. Benirschke K, Kaufmann P (eds) (2000) Pathology of the human placenta. Springer-Verlag, New York

    Google Scholar 

  5. Landy HJ, Neith LG (1998) The vanishing twin: a review. Hum Reprod Update 4:177–183

    Article  PubMed  CAS  Google Scholar 

  6. Andersen AN, Gianaroli L, Felberbaum R et al (2005) Assisted reproductive technology in Europe, 2001. Results generated from European registers by ESHRE. Hum Reprod 20:1158–1176

    Article  PubMed  Google Scholar 

  7. Simón C, Landeras J, Zuzuarregui JL et al (1999) Early pregnancy losses in in vitro fertilization and oocyte donation. Fertil Steril 72:1061–1065

    Article  PubMed  Google Scholar 

  8. Kingdom CP, Nevi O, Murphy KE (2005) Discordant growth in twins. Prenat Diag 25:759–765

    Article  Google Scholar 

  9. Naeye RL, Letts HW (1964) Body measurements of fetal and neonatal twins. Arch Pathol 77:393–396

    PubMed  CAS  Google Scholar 

  10. Galea P, Barigye O, Wee L et al (2008) The placenta contributes to activation of the renin angiotensin system in twin-to-twin transfusion syndrome. Placenta 29:734–742

    Article  PubMed  CAS  Google Scholar 

  11. Nicolini U, Poblete A (1999) Single intrauterine death in monochorionic twin pregnancies. Ultrasound Obstet Gynecol 14:297–301

    Article  PubMed  CAS  Google Scholar 

  12. Lopriore E, Nagel HT, Vandenbussche FP et al (2003) Long term neurodevelopmental outcome in twin-to-twin transfusion syndrome. Am J Obstet Gynecol 189:1314–1319

    Article  PubMed  Google Scholar 

  13. Denbow M, Fogliani R, Kyle P et al (1998) Haematological indices at fetal blood sampling in monochorionic pregnancies complicated by feto-fetal transfusion syndrome. Prenat Diagn 18:941–946

    Article  PubMed  CAS  Google Scholar 

  14. Senat M, Deprest J, Bulvain M et al (2004) Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndrome. N Engl J Med 351:136–144

    Article  PubMed  CAS  Google Scholar 

  15. Quintero RA, Moeales WJ, Allen MH et al (1999) Staging of twin-to-twin transfusion syndrome. J Perinatol 19:550–555

    Article  PubMed  CAS  Google Scholar 

  16. Stirnemann JJ, Mougeot M, Proulx F et al (2010) Profiling fetal cardiac function in twin-twin transfusion syndrome. Ultrasound Obstet Gynecol 35:19–27

    Article  PubMed  CAS  Google Scholar 

  17. Fusi L, McParland P, Fisk N et al (1991) Acute twin-to-twin transfusion: a possible mechanism for brain damaged survivors after intrauterine death of a monochorionic twin. Obstet Gynecol 78:517–520

    PubMed  CAS  Google Scholar 

  18. Hall JG (2003) Twinning. Lancet 362:735–743

    Article  PubMed  Google Scholar 

  19. Karatza AA, Wolfenden JL, Taylor MJO et al (2002) Influence of twin-to-twin transfusion syndrome on fetal cardiovascular structure and function: prospective case-control study of 136 monochorionic twin pregnancies. Heart 88:271–277

    Article  PubMed  CAS  Google Scholar 

  20. Rustico MA, Baietti MG, Coviello D et al (2005). Managing twins discordant for fetal anomalies. Prenat Diagn 25:766–771

    Article  PubMed  CAS  Google Scholar 

  21. Hack KE, Derks JB, Schaap AH et al (2009) Perinatal outcome of monoamniotic twin pregnancies. Obstet Gynecol 113:353–360

    PubMed  Google Scholar 

  22. De Lia JE, Kuhlmann RS, Harstad TW, Cruikshank DP (1995) Fetoscopic laser ablation of placental vessels in severe previable twin-twin transfusion syndrome. Am J Obstet Gynecol 172(4 Pt 1):1202–1208

    Article  PubMed  Google Scholar 

  23. Quintero RA, Comas C, Bornick PW et al (2000) Selective versus non-selective laser photocoagulation of placental vessels in twin-to-twin transfusion syndrome. Ultrasound Obstet Gynecol 16:230–236

    Article  PubMed  CAS  Google Scholar 

  24. Mari G, Roberts A, Detti L et al (2001) Perinatal morbidity and mortality rates in severe twin-twin transfusion syndrome: results of the International Amnioreduction Registry. Am J Obstet Gynecol 185:708–715

    Article  PubMed  CAS  Google Scholar 

  25. Roberts D, Gates S, Kilby M, Neilson JP (2008) Interventions for twin-twin transfusion syndrome: a Cochrane review. Ultrasound Obstet Gynecol 31:701–711

    Article  PubMed  CAS  Google Scholar 

  26. Yamamoto M, Ville Y (2007) Laser treatment in twin-to-twin transfusion syndrome. Sem Fetal Neonat Med 12:450–457

    Article  Google Scholar 

  27. Lopriore E, Middeldorp JM, Sueters M et al (2007) Long-term neurodevelopmental outcome in twin-to-twin transfusion syndrome treated with fetoscopic laser surgery. Am J Obstet Gynecol 196:231.e1–4

    Article  Google Scholar 

  28. De Lia JE, Kuhlmann RS, Lopez KP (1999) Treating previable twin-twin transfusion syndrome with fetoscopic laser surgery: outcomes following the learning curve. J Perinat Med 27:61–67

    Article  PubMed  Google Scholar 

  29. Yamamoto M, El Murr L, Robyr R et al (2005) Incidence and impact of perioperative complications in 175 fetoscopy-guided laser coagulations of chorionic plate anastomoses in fetofetal transfusion syndrome before 26 weeks of gestation. Am J Obstet Gynecol 193(3 Pt 2):1110–1116

    Article  PubMed  Google Scholar 

  30. Robyr R, Lewi L, Salomon LJ et al (2006) Prevalence and management of late fetal complications following successful selective laser coagulation of chorionic plate anastomoses in twin-to-twin transfusion syndrome. Am J Obstet Gynecol 194:796–803

    Article  PubMed  Google Scholar 

  31. Chang YL, Chmait RH, Bornick PW et al (2006) The role of laser surgery in dissecting the etiology of absent or reverse end-diastolic velocity in the umbilical artery of the donor twin in twin-twin transfusion syndrome. Am J Obstet Gynecol 195:478–483

    Article  PubMed  Google Scholar 

  32. Hecher K, Plath H, Bregenzer T et al (1999) Endoscopic laser surgery versus serial amniocenteses in the treatment of severe twin-twin transfusion syndrome. Am J Obstet Gynecol 180(3 Pt 1):717–724

    Article  PubMed  CAS  Google Scholar 

  33. Hecher K, Diehl W, Zikulnig L et al (2000) Endoscopic laser coagulation of placental anastomoses in 200 pregnancies with severe mid-trimester twin-to-twin transfusion syndrome. Eur J Obstet Gynecol Reprod Biol 92:135–139

    Article  PubMed  CAS  Google Scholar 

  34. Huber A, Diehl W, Bregenzer T (2006) Stage-related outcome in twin-twin transfusion syndrome treated by fetoscopic laser coagulation. Obstet Gynecol 108:333–337

    Article  PubMed  Google Scholar 

  35. Becker J, Hernandez-Andrade E, Muñoz-Abellana B (2006) Stage-dependent fetal umbilical blood flow changes induced by laser therapy and amniodrainage in twin-to-twin transfusion syndrome. Ultrasound Obstet Gynecol 28:674–680

    Article  PubMed  CAS  Google Scholar 

  36. Barrea C, Hornberger LK, Alkazaleh F (2006) Impact of selective laser ablation of placental anastomoses on the cardiovascular pathology of the recipient twin in severe twin-twin transfusion syndrome. Am J Obstet Gynecol 195:1388–1395

    Article  PubMed  Google Scholar 

  37. Nicolini U, Poblete A, Boschetto C et al (2001) Complicated monochorionic twin pregnancies: Experience with bipolar cord coagulation. Am J Obstet Gynecol 185:703–707

    Article  PubMed  CAS  Google Scholar 

  38. Rossi CA, D’Addario V (2009) Umbilical cord occlusion for selective feticide in complicated monochorionic twins: a systematic review of literature. Am J Obstet Gynecol 200:123–129

    Article  PubMed  Google Scholar 

  39. Quintero RA (2003) Treatment of previable premature ruptured membranes. Clin Perinatol 30:573–589

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Obstetrics and Gynaecology Clinical Unit, Buzzi Children’s Hospital Department of Clinical Sciences, University of Milan, Milan, Italy

    Maria Angela Rustico

Authors
  1. Maria Angela Rustico
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Mariano Lanna
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Enrico Ferrazzi
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Pediatrics, Obstetrics and Reproductive Medicine, Division of Neonatology, University of Siena General Hospital S. Maria alle Scotte Azienda Ospedaliera Universitaria Senese, Siena, Italy

    Giuseppe Buonocore (Professor of Pediatrics and Neonatology, Head of School of Pediatrics) (Professor of Pediatrics and Neonatology, Head of School of Pediatrics)

  2. University of Siena, Siena, Italy

    Rodolfo Bracci (Formerly Professor of Pediatrics and Head of Department of Pediatrics, Obstetrics and Reproductive Medicine) (Formerly Professor of Pediatrics and Head of Department of Pediatrics, Obstetrics and Reproductive Medicine)

  3. University of Liverpool, UK

    Michael Weindling (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery) (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery)

  4. Department of Women’s and Children’s Health, Institute of Translational Medicine, Liverpool, UK

    Michael Weindling (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery) (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery)

  5. Liverpool Women’s Hospital, Liverpool, UK

    Michael Weindling (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery) (Professor of Perinatal Medicine, Director of Postgraduate Research, Head of School of Paediatrics Mersey Deanery)

Rights and permissions

Reprints and permissions

Copyright information

© 2012 Springer-Verlag Italia

About this chapter

Cite this chapter

Rustico, M.A., Lanna, M., Ferrazzi, E. (2012). Multiple Pregnancies. In: Buonocore, G., Bracci, R., Weindling, M. (eds) Neonatology. Springer, Milano. https://doi.org/10.1007/978-88-470-1405-3_10

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-1405-3_10

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-1404-6

  • Online ISBN: 978-88-470-1405-3

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation