Skip to main content

Controlled Mechanical Ventilation in ARDS

  • Chapter
Respiratory System and Artificial Ventilation

Abstract

Acute respiratory distress syndrome (ARDS) is a severe form of hypoxaemic respiratory failure that is associated with several critical diseases, such as trauma, inhalation injury, shock and pulmonary and extrapulmonary infections. ARDS has been classified into two forms: primary (caused by an insult in the lung) and secondary (caused by an indirect insult, e.g. sepsis or acute pancreatitis, followed by an acute systemic inflammatory response). Lung disease originating from an inflammatory response has several degrees of severity. In the presence of sepsis, these range from a subclinical expression of pulmonary damage to overt respiratory failure. The most feared complication of sepsis is ARDS, a severe form of acute lung injury (ALI).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Bernard GR, Artigas A, Brigham GL et al (1994) The American-European consensus conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 149:818–824

    PubMed  CAS  Google Scholar 

  2. Thomsen GE, Morris AH (1995) Incidence of the adult respiratory distress syndrome in the state of Utah. Am J Respir Crit Care Med 152:965–971

    PubMed  CAS  Google Scholar 

  3. Marino PL (2007) The ICU Book. Lippincott Williams & Wilkins, Philadelphia

    Google Scholar 

  4. Montgomery AN, Stager MA (1985) Causes of mortality in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 132:485–489

    PubMed  CAS  Google Scholar 

  5. Murray JF, Matthay MA (1988) An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 138:720–723

    PubMed  CAS  Google Scholar 

  6. Sloan PJ, Gee MH (1992) A multicenter registry of patients with acute respiratory distress syndrome: physiology and outcome Am Rev Respir Dis 142:1250–1257

    Google Scholar 

  7. Doyle RL, Szaflarski N (1995) Identification of patients with acute lung injury. Predictors of mortality. Am J Respir Crit Care Med 152:1818–1824

    PubMed  CAS  Google Scholar 

  8. Demling RH (1995) The modern version of the adult respiratory distress syndrome. Annu Rev Med 46:193–202

    Article  PubMed  CAS  Google Scholar 

  9. Matthay MA, Wiener Kronish JP (1990) Intact epithelial barrier function is critical for the resolution of alveolar edema in humans. Am Rev Respir Dis 142:1250–1257

    PubMed  CAS  Google Scholar 

  10. Mc Hugh LG, Milberg JA (1994) Recovery of function in survivors of the acute respiratory distress syndrome. Am J respir Crit Care Med 150:90–94

    CAS  Google Scholar 

  11. Davidson TA, Caldwell ES (1999) Reduced quality of life in survivors of acute respiratory distress syndrome compared with critically ill control patients JAMA 281:354–360

    Article  PubMed  CAS  Google Scholar 

  12. Lumb AB (ed) (2005) Nunn’s applied respiratory physiology, 6th edition. Elsevier, Philadelphia

    Google Scholar 

  13. Steinberg KP, Milberg JA (1988) Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome. Am Rev Respir Dis 138:720–723

    Google Scholar 

  14. Pelosi P, Caironi P, Gattinoni L (2001) Pulmonary and extrapulmonary forms of acute respiratory distress syndrome. Semin Respir Crit Care Med 22(3)259–268

    Article  PubMed  CAS  Google Scholar 

  15. Pelosi P, D’Onofrio D, Chiumello D et al (2003) Pulmonary and extrapulmonary acute respiratory distress syndrome are different. Eur Respir J 22(Suppl 42):48s–56s

    Article  Google Scholar 

  16. Gattinoni L, Pesenti A, Bombino M (1988) Relationships between lung computed tomographic density, gas exchange and PEEP in acute respiratory failure. Anesthesiology 69:824–832

    Article  PubMed  CAS  Google Scholar 

  17. Webb HH, Tierney DF (1974) Experimental pulmonary edema due to intermittent positive pressure ventilation with high inflation pressures: protection by positive and-expiratory pressure. Am Rev Respir Dis 110:556–565

    PubMed  CAS  Google Scholar 

  18. Wright PE, Bernard GR (1989) The role of airflow resistance in patients with the adult respiratory distress syndrome. Am Rev Respir Dis 139:1169–1174

    PubMed  CAS  Google Scholar 

  19. Gattinoni L, Caironi P, Cressoni M et al (2006) Lung recruitment in patients with the acute respiratory distress syndrome. N Eng J Med 354:1775–1786

    Article  CAS  Google Scholar 

  20. Falke KJ (ed) (1992) Lung biology in heath and disease. Philadelphia, Saunders

    Google Scholar 

  21. The Acute Respiratory Distress Syndrome Network (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 342:1301–1308

    Article  Google Scholar 

  22. Villar J, Kacmarek RM, Pérez-Méndex Lina et al (2006) A high positive end-expiratory pressure, low tidal volume ventilatory strategy improves outcome in persistent acute respiratory distress syndrome: arandomized controlled trial. Crit Care Med 34(5):1311–1318

    Article  PubMed  Google Scholar 

  23. Decailliot F, Demoule A, Maggiore SM et al (2006) Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome. Intensive Care Med 32:1322–1328

    Article  PubMed  Google Scholar 

  24. Kallet RH, Branson RD (2007) Do the NIH ARDS Clinical Trials Network PEEP/FiO2 Tables provide the best evidence-based guide to balancing PEEP and FIO2 settings in adults? Respiratory Care 52(4):461–475

    PubMed  Google Scholar 

  25. Ferguson ND, Frutos-Vivar F, Esteban A et al (2005) Airway pressure, tidal volumes and mortality in patients with acute respiratory distress syndrome Crit Care Med. 33(1):21–30

    Article  PubMed  Google Scholar 

  26. Alsous F, Amoateng Adjepong Y(1999) Noninvasive ventilation: experience at a community teaching hospital. Intensive Care Med 25:459–463

    Article  Google Scholar 

  27. Patrick W, Webster K (1996) Noninvasive positive-pressure ventilation in acute respiratory distress without prior chronic respiratory failure. Am J Respir Crit Care Med 153:1005–1011

    PubMed  CAS  Google Scholar 

  28. Agarwal R, Reddy C, Aggarwal AN (2006) Is there a role for noninvasive ventilation in acute respiratory distress syndrome? A meta-analysis. Respir Med 100(12):2235–2238

    Google Scholar 

  29. Antonelli M, Conti G, Esquinas A et al (2007) A multiple-center survey on the use in clinical practice of noninvasive ventilation as a first-line intervention for acute respiratory distress syndrome Crit Care Med 35(1):18–25

    Article  PubMed  Google Scholar 

  30. Prella M, Feihl F, Domenighetti G (2002) Effect of short-term pressure-controlled ventilation on gas exchange, airway pressures and gas distribution in patients with acute lung injury/ARDS. Comparison with volume-controlled ventilation. Chest 122:1382–1388

    Article  PubMed  Google Scholar 

  31. Branson RD, Catburn RL (2007) Should adaptive pressure control modes be utilized for virtually all patients receiving mechanical ventilation? Respir Care 52(4):478–485

    PubMed  Google Scholar 

  32. Merker D, Groll JR (2001) Prospective trial of high-frequency oscillation in adults with acute respiratory distress syndrome Crit Care Med 29:1360–1369

    Article  PubMed  Google Scholar 

  33. Wunsch H, Mapstone J, Takala J (2005) High-frequency ventilation versus conventional ventilation for the treatment of acute lung injury and acute respiratory distress syndrome: a systematic review and Cochrane analysis. Anesth Analg 100(6):1765–1772

    Article  PubMed  Google Scholar 

  34. Bollen CW, van Well GTJ, Sherry T et al (2005) High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial. Critical Care 9:R430–R439

    Article  PubMed  Google Scholar 

  35. Ferguson ND, Chicche JD, Kacmarek RM et al (2005) Combining high-frequency oscillatory ventilation and recruitment maneuvers in adults with early acute respiratory distress syndrome: the Treatment with Oscillation and an Open Lung Strategy (TOOLS) trial pilot study. Crit Care Med 33(3):479–486

    Article  PubMed  Google Scholar 

  36. Lucangelo U, Fontanesi L (2003) High frequency ventilation, principles and technique. Minerva Anesthesiol 69:841–851

    CAS  Google Scholar 

  37. Birnkrant DJ, Pope JF (1996) Persistent pulmonary consolidation treated with intrapulmonary percussive ventilation: a preliminary report. Pediatr Pulomonol 21:246–249

    Article  CAS  Google Scholar 

  38. Reper P, Dankaert R(1998) The usefulness of high frequency percussive ventilation during acute respiratory failure after smoke inhalation. Burns 24:34–38

    Article  PubMed  CAS  Google Scholar 

  39. Gattinoni L, Tognoni G, Pesenti A et al (2001) Effect of prone positioning on the survival of patients with acute respiratory failure. N Engl J Med 345(8):568–573

    Article  PubMed  CAS  Google Scholar 

  40. Mancebo J, Fernández R, Blanch L et al (2006) A multicenter trial of prolonged prone ventilation in severe acute respiratory distress syndrome. Am J Respir Crit Care Med 173:1233–1239

    Article  PubMed  Google Scholar 

  41. Voggenreiter G, Aufmkolk M, Stiletto RJ et al (2005) Prone positioning improves oxygenation in post-traumatic lung injury-a prospective randomized trial. J Trauma 59(2):333–341

    Article  PubMed  Google Scholar 

  42. Papazian L, Gainnier M, Marin V et al (2005) Comparison of prone positioning and highfrequency oscillatory ventilation in patients with acute respiratory distress syndrome. Crit Care Med 33(10):2162–2171

    Article  PubMed  Google Scholar 

  43. Demory D, Michelet P, Arnal JM et al (2007) High-frequency oscillatory ventilation following prone positioning prevents a further impairment in oxygénation. Crit Care Med 35(1):106–111

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2008 Springer

About this chapter

Cite this chapter

Lucangelo, U., Gramaticopolo, S., Bacer, B. (2008). Controlled Mechanical Ventilation in ARDS. In: Lucangelo, U., Pelosi, P., Zin, W.A., Aliverti, A. (eds) Respiratory System and Artificial Ventilation. Springer, Milano. https://doi.org/10.1007/978-88-470-0765-9_9

Download citation

  • DOI: https://doi.org/10.1007/978-88-470-0765-9_9

  • Publisher Name: Springer, Milano

  • Print ISBN: 978-88-470-0764-2

  • Online ISBN: 978-88-470-0765-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics