Abstract
Intestinal transplantation (ITx) has become an alternative for patients with permanent intestinal failure who are dependent on parenteral nutrition (PN) [1], Our center has been involved in the management of pediatric patients with intestinal failure for a long time. After developing a home PN program [2, 3], we started ITx in 1987 using cyclosporine [4]. One of our earliest patients still survives with a fully functioning graft 12 years later [5]. With the development of FK506 (tacrolimus) in the early 1990s [6], we restarted our ITx program. We now report the results of the largest current European series of consecutive intestinal transplantations in pediatric patients at the Necker-Enfants Malades University Hospital in Paris.
Key words
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Goulet O (1998) Intestinal failure in children. Transplant Proc 30:2523–2525
Ricour C, Gorski AM, Goulet O, et al. (1990) Home parenteral nutrition in children: 8 years of experience with 112 patients. Clin Nutr 9:65–71
Colomb V, Goulet O, Ricour C (1998) Home enteral and parenteral nutrition. Baillière’s Clin Gastroenterol 122:877–894
Goulet O, Michel JL, Jan D, et al. (1997) Intestinal transplantation in pediatric patients: the European experience. Transplant Proc 29:1785–1786
Goulet O, Révillon Y, Brousse N, et al. (1992) Successful small bowel transplantation in an infant. Transplantation 53:940–943
Todo S, Tsakis A, Abu-Elmagd K, et al. (1992) Cadaveric small bowel and small bowel-liver transplantation in humans. Transplantation 53:369–376
Grant D (1996) Intestinal Transplantation Registry on behalf of the current results of intestinal transplantation. Lancet 347:1801–1803
Grant D (1999) Intestinal transplantation: 1997 report of the International Registry. Transplantation 15:1061–1064
Langnas AN, Shaw BW, Antonson DL, et al. (1996) Preliminary experience with intestinal transplantation in infants and children. Pediatrics 97:443–448
Karatzas T, Khan F, Tzakis AG (1997) Clinical intestinal transplantation—experience in Miami. Transplant Proc 29:1787–1789
Atkison P, Williams S, Wall S, et al. (1998) Results of pediatric small bowel transplantation in Canada. Transplant Proc 30:2521–2522
Abu-Elmagd K, Reyes J, Todo S, et al. (1998) Clinical intestinal transplantation: new perspectives and immunologic considerations. J Am Coll Surg 186:512–525
Reyes J, Bueno J, Kocoshis S, et al. (1998) Current status of intestinal transplantation in children. J Pediatr Surg 243–254
Farmer DG, McDiarmid SV, Smith C, et al. (1998) Experience with combined liver-small intestine transplantation at the University of California, Los Angeles. Transplant Proc 30:2533–2534
Sudan DL, Kaufman S, Shaw BW, et al. (2000) Intestinal transplantation: for intestinal failure. Am J Gastroenterol 95:1506–1515
Goulet O, Jan D, Lacaille F, et al. (1999) Intestinal transplantation in children: preliminary experience in Paris. J Parenter Enter Nutr 23(Suppl.):S121–S125
Bueno J, Ohwada S, Kocoshis S, et al. (1999) Factors impacting the survival of children with intestinal failure referred for intestinal transplantation. J Pediatr Surg 34:27–33
Beath SV, Booth IW, Murphy MS, et al. (1995) Nutritional care and candidates for small bowel transplantation. Arch Dis Child 73:348–350
Beath SV, Brook GA, Kelly DA, et al. (1998) Demand for pediatric small bowel transplantation in the United Kingdom. Transplant Proc 30:2531–2532
Colomb V, Jobert A, Lacaille F, et al. (1999) Parenteral nutrition associated liver disease in children: natural history and prognosis. J Pediatr Gastroenterol Nutr 28:577 (abstract)
Filston HC, Colombani PM (1996) Preliminary experience with intestinal transplantation in infants and children. Pediatrics 97:583–584
Goulet O, Brousse N, Révillon Y, et al. (1993) Pathology of human intestinal transplantation. In: Grant D, Wood RFM (eds) Small bowel transplantation. Edward Arnold, London, pp 112–120
Kusne S, Manez R, Frye BL, et al. (1997) Use of DNA amplification for diagnosis of cytomegalovirus enteritis after intestinal transplantation. Gastroenterology 112: 1121–1128
Green M, Bueno J, Sigurdsson L, et al. (1999) Unique aspects of the infectious complications of intestinal transplantation. Curr Opin Organ Transplant 4:361–367
Patel R, Snydman DR, Rubin RH, et al. (1996) Cytomegalovirus prophylaxis in solid organ transplant recipients. Transplantation 61:1279–1289
Reyes J, Tzakis A, Bonet H, et al. (1994) Lymphoproliferative disease after intestinal transplantation under primary FK 506 immunosuppression. Transplant Proc 26: 1426–1427
Finn L, Reyes J, Bueno J, et al. (1998) Epstein-Barr virus infection in children after transplantation of the small intestine. Am J Surg Pathol 22:299–309
Green M, Reyes J, Jabbour N, et al. (1996) Use of quantitative PCR to predict onset of Epstein-Barr viral infection and post-transplant lymphoproliferative disease after intestinal transplantation in children. Transplant Proc 28:2759–2760
Kim J, Fryer J, Craig RM (1998) Absorptive function following small intestinal transplantation. Dig Dis Sci 43:1925–1930
Kaufman SS, Lyden ER, Brown CR, et al. (2000) Disaccharidase activities and fat assimilation in pediatric patients after intestinal transplantation. Transplantation 15:362–365
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2002 Springer Japan
About this paper
Cite this paper
Goulet, O. et al. (2002). Intestinal Transplantation in Children: Experience of a Single Center in Paris. In: Kitajima, M., Shimazu, M., Wakabayashi, G., Hoshino, K., Tanabe, M., Kawachi, S. (eds) Current Issues in Liver and Small Bowel Transplantation. Keio University International Symposia for Life Sciences and Medicine, vol 9. Springer, Tokyo. https://doi.org/10.1007/978-4-431-67889-2_14
Download citation
DOI: https://doi.org/10.1007/978-4-431-67889-2_14
Publisher Name: Springer, Tokyo
Print ISBN: 978-4-431-68005-5
Online ISBN: 978-4-431-67889-2
eBook Packages: Springer Book Archive