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Extremophiles Handbook pp 213–227Cite as

Beta-Cyclomaltodextrin Glucanotransferase of a Species of Alkaliphilic Bacillus for the Production of Beta-Cyclodextrin

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Isolation of Alkaliphilic Bacteria Producing β-CGTases

Cyclomaltodextrin glucanotransferase (CGTase) [systematic name:1,4-α- d- glucan 4-α-d-(1,4-α-d-glucano)-transferase (cyclizing)], which is also called as cyclodextrin glycosyltransferase or cyclomaltodextrin glycosyltransferase, is a member of the α-amylase superfamily and belongs to the transferase group of enzymes (EC.2.4.1.19). This enzyme catalyzes the intramolecular transglycosylation to form cyclodextrins (CDs), which are nonreducing and cyclic maltooligosaccharides composed of 6–12 glucose molecules linked by the α-1,4-glucopyranosidic linkage, from starch and related carbohydrates (French 1957, 1962; Thoma and Stewwart 1965; Pulley and French 1961). Major products obtained from starch by the enzyme action are cyclomalto-hexaose (α-CD), -heptaose (β-CD), and -octaose (γ-CD), and larger CDs (δ-, ε-, ζ-, η-CD, and so on) are also formed during the reaction as minor products (French et al. 1965). Small amounts of...

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  1. Department of Research Support, Japan Agency for Marine-Earth Science and Technology (JAMSTEC), 2-15 Natsushima-cho, Yokosuka, Kanagawa, 237-006, Japan

    Dr. Nobuyuki Nakamura

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  1. Extremobiosphere Research Center, Japan Agency for Marine-Earth Science and Technology (JAMSTEC) Yokohama, Professor Emeritus of Tokyo Institute of Technology, Tokyo, Japan

    Koki Horikoshi

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Nakamura, N. (2011). Beta-Cyclomaltodextrin Glucanotransferase of a Species of Alkaliphilic Bacillus for the Production of Beta-Cyclodextrin. In: Horikoshi, K. (eds) Extremophiles Handbook. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53898-1_11

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