Abstract
In this chapter a three-dimensional model of ellipsoidal cells is presented and used to study how cell-cell signaling, cell adhesion, chemotaxis and differentiation all work together in a coordinated fashion to give rise to the developed organism. The Dictyostelium discoideum is used as a model system, since it is simple, yet has all the basic cell-cell interactions. Another goal of introducing this model is to achieve visualization of cell movements and signal propagation in 3-D space.
This work was completed with the support of NSERC grant number RGPIN249789.
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Palsson, E. (2007). A 3-D Deformable Ellipsoidal Cell Model with Cell Adhesion and Signaling. In: Anderson, A.R.A., Chaplain, M.A.J., Rejniak, K.A. (eds) Single-Cell-Based Models in Biology and Medicine. Mathematics and Biosciences in Interaction. Birkhäuser Basel. https://doi.org/10.1007/978-3-7643-8123-3_12
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DOI: https://doi.org/10.1007/978-3-7643-8123-3_12
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