Surgical Management of Intracranial Gliomas — Does Radical Resection Improve Outcome?

  • E. R. Laws
  • M. E. Shaffrey
  • A. Morris
  • F. A. AndersonJr
Conference paper

DOI: 10.1007/978-3-7091-6043-5_7

Part of the Acta Neurochirurgica Supplements book series (NEUROCHIRURGICA, volume 85)
Cite this paper as:
Laws E.R., Shaffrey M.E., Morris A., Anderson F.A. (2003) Surgical Management of Intracranial Gliomas — Does Radical Resection Improve Outcome?. In: Bernays R.L., Imhof HG., Yonekawa Y. (eds) Intraoperative Imaging in Neurosurgery. Acta Neurochirurgica Supplements, vol 85. Springer, Vienna

Abstract

This paper discusses the arguments for and against radical tumor resection as a strategy for treatment of cerebral gliomas.

Method. Data from the Glioma Outcome Project were analyzed to determine whether survival could be related to extent of resection in 666 patients treated by biopsy or resection for malignant cerebral gliomas.

Findings. Consistent survival advantages were noted for those patients treated with resection.

Interpretation. This observational study, although undoubtedly reflecting selection bias, provides data that support resection as a major factor in survival after surgery for malignant gliomas.

Keywords

Malignant glioma Glioblastoma Outcome survival 

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Copyright information

© Springer-Verlag/Wien 2003

Authors and Affiliations

  • E. R. Laws
    • 1
  • M. E. Shaffrey
    • 1
  • A. Morris
    • 1
  • F. A. AndersonJr
    • 2
  1. 1.Department of NeurosurgeryHealth Science Centre, University of Charlottesville VirginiaUSA
  2. 2.Center for Outcomes ResearchUniversity of Massachusetts Medical SchoolWorcesterUSA

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