Skip to main content

Osteoporosis

  • Chapter
  • First Online:
Drug Therapy for the Elderly
  • 1892 Accesses

Abstract

Osteoporosis is an important age-related disease; its largest incidence occurs in postmenopausal women. Social and economical consequences are considerable as it is frequent and leads to fractures, particularly of the hip and vertebrae. In the elderly, and particularly the very elderly, fracture morbidity leads to mortality as they may be complicated by pneumonia or venous thromboembolism due to immobilization. The disease is characterized by a progressive reduction of bone density, which not only includes demineralization but also structural rarification. Typical risk factors apart from female sex are

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Chrischilles EA, Butler CD, Davis CS, Wallace RB (1991) A model of lifetime osteoporosis impact. Arch Intern Med 151:2026–2032

    Article  PubMed  CAS  Google Scholar 

  • Donaldson MG, Cawthon PM, Lui LY et al (2010) Estimates of the proportion of older white men who would be recommended for pharmacologic treatment by the new U.S. National Osteoporosis Foundation guidelines. J Bone Miner Res 25:1506–1511

    Article  PubMed  Google Scholar 

  • Duque G, Mallet L, Roberts A, Gingrass S, Kremer R, Sainte-Marie LG, Kiel DP (2007) To treat or not to treat, that is the question: proceedings of the Quebec symposium for the treatment of osteoporosis in long-term care institutions, Saint- Hyacinthe, Quebec, November 5, 2004. J Am Med Dir Assoc 8(3 Suppl 2):e67–e73

    Article  PubMed  Google Scholar 

  • Looker AC, Orwoll ES, Johnston CC Jr et al (1997) Prevalence of low femoral bone density in older U.S. adults from NHANES III. J Bone Miner Res 12:1761–1768

    Article  PubMed  CAS  Google Scholar 

  • Lyles KW, Colon-Emeric CS, Magaziner JS et al (2007) HORIZON Recurrent Fracture Trial. Zoledronic acid and clinical fractures and mortality after hip fracture. N Engl J Med 357:1799–1809

    Article  PubMed  CAS  Google Scholar 

  • National Osteoporosis Foundation (2002) America’s bone health: the state of osteoporosis and low bone mass in our nation. National Osteoporosis Foundation, Washington, DC

    Google Scholar 

  • National Osteoporosis Foundation (2010) Clinician’s guide to prevention and treatment of osteoporosis. National Osteoporosis Foundation, Washington, DC

    Google Scholar 

  • U.S. Department of Health and Human Services (2004) Bone health and osteoporosis: a report of the surgeon general. U.S. Department of Health and Human Services, Office of the Surgeon General, Rockville

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Martin Wehling .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Wien

About this chapter

Cite this chapter

Wehling, M. (2013). Osteoporosis. In: Wehling, M. (eds) Drug Therapy for the Elderly. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0912-0_12

Download citation

  • DOI: https://doi.org/10.1007/978-3-7091-0912-0_12

  • Published:

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-7091-0911-3

  • Online ISBN: 978-3-7091-0912-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics