Abstract
Human cytomegalovirus (CMV) is the main cause of congenital virus infection in developed countries, leading to psychomotor impairment, deafness and blindness. In Germany each year an estimated 6,500 children are born with congenital CMV infection, causing an estimated 40 deaths and leaving approximately 1,200 children (primary infected and from seropositive women) with permanent disabilities such as hearing or vision loss or mental retardation. More children are affected by serious CMV-related disabilities than by several better-known childhood maladies, including Down syndrome[1].
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsPreview
Unable to display preview. Download preview PDF.
References
Cannon MJ, Finn Davis K (2005) Washing our hands of the congenital cytomegalovirus disease epidemic. BMC Public Health 5:70
Ludwig A, Hengel H (2009) Epidemiological impact and disease burden of congenital cytomegalovirus infection in Europe. Eurosurveill Vol. 14, Issue 9
Porath A, McNutt RA, Smiley LM, et al. (1990) Effectiveness and cost benefit of a proposed live cytomegalovirus vaccine in the prevention of congenital disease. Rev Infect Dis 12(1):31–40
Gazelle GS, McMahon PM, Siebert U, et al. (2005) Cost-effectiveness analysis in the assessment of diagnostic imaging technologies. Radiol 235(2):361–370
Akobundu E, Ju J, Blatt L, et al. (2006) Cost-of-Illness Studies — A Review of Current Methods. Pharmaco Econ 24(9):869–890
Azam AZ, Vial Y, Fawer CL, Zufferey J, Hohlfeld P (2001) Prenatal Diagnosis of Congenital Cytomegalovirus Infection. Obstet Gynecol Vol. 97, No. 3
Halwachs-Baumann G, Genser B (2003) Die konnatale Zytomegalievirusinfektion Epidemiologie — Diagnose — Therapie. Springer, Wien
Halwachs-Baumann G, Ludwig A, Hengel H (2006) Cytomegalie-Virus (CMV) — Infektionen in der Schwangerschaft. www.dgk.de
Ornoy A, Diav-Citrin O (2006) Fetal effects of primary and secondary cytomegalovirus infection in pregnancy. Reprod Toxicol 21
Dollard S, Grosse S, Ross D (2007) New estimates of the prevalence of neurological and sensory sequelae and mortality associated with congenital cytomegalovirus infection. Rev Med Virol 17
Ramsay M, Miller E, Peckham C (1991) Outcome of confirmed symptomatic congenital cytomegalovirus infection. Arch Dis Child 66
Schöffski O, Schulenburg Graf von der JM (2008) Gesundheitsökonomische Evaluation
Schulenburg Graf von der JM, Greiner W, Jost F, et al. (2007) Deutsche Empfehlungen zur gesundheitsökonomischen Evaluation-dritte und aktualisierte Fassung des Hannoveraner Konsens. Gesundh ökon Qual Manag 12
Statistisches Bundesamt Deutschland http://www.destatis.de/jetspeed/portal/cms/Sites/destatis/Internet/DE/Navigation/Navigationsknoten__Startseitel.psml
WHO. Global Burden of Disease, http://www.who.int/topics/global_burden_of_disease/en/
Institut für Gesundheitsökonomik München (2008) Bundeseinheitlicher Basisfallwert für Krankenhausleistungen und seine Konsequenzen: ein falscher Weg aus ordnungspolitischer Sicht
AOK (2008) Gesundheitskasse für Niedersachsen-Leistungen Hörgeräte. www.aok.de
Sohlbach I, Burgdörfer J, Lang J (2008) Blindheit und Sehbehinderung, www.polizei-projekte.nrw.de
Leitlinie der Gesellschaft für Neonatologie u Pädiatrische Intensivmedizin (2004) Zerebrale Anfälle beim Neugeborenen
Leitlinie der Gesellschaft für Neuropädiatrie (2001) Wahrnehmungsstörungen
Lange K, Danne T, Kordonouri O, et al. (2004) Diabetesmanifestation im Kindesalter: Alltagsbelastungen und berufliche Entwicklung der Eltern. Dtsch Med Wochenschr 129
Lafuma A, Brezin A, Lopatriello S, et al. (2006) Evalutaion of Non-Medical Costs Associated with Visual Impairment in Four European Countries. Pharmaco Econ 24(2)
Preuss-Lausitz U. (2004) Zur Frage der Kosten gemeinsamer schulischer Bildung. http://www.ewi.tu/belin.de/files/resourcesmodule/@random435c8d75c8731/1131958614_Kostenll_05.ppt
AOK (2009) Allg. Pflegesatz, Vollstationäre Pflege. www.aok-pflegenavigator.de
Munro SC, Hall B, Whybin LR, et al. (2005) Diagnosis of and Screening for Cytomegalovirus Infection in Pregnant Women. J Clin Microbiol, Vol. 43, No. 9
Lazzarotto T, Guerra B, Lanari M, et al. (2008) New advances in the diagnosis of congenital cytomegalovirus infection. J Clin Virol 41
Curdt I, Herzogenrath J, Bernhardt S, Braun HB, Eichler R, Maine GT, Hausmann M, Stricker Rt, Stricker Rn, Lazzarotto T, Christ H (2006) Preliminary Evaluation of the Abbott ARCHITECT Anti Cytomegalovirus IgG, IgM and IgG Avidity Assays Linked by an Automated Reflex Algorithm, American Association for Clinical Chemistry Annual Meeting, Chicago
Nigro G, Adler SP, La Torre R, Best M (2005) Passive immunization during pregnancy for congenital cytomegalovirus infection. N Engl J Med 353:1350–1362
Drummond MF (1986) Studies in economic appraisal in health care, Vol 2. Oxford University Press, Oxford New York Tokyo
Drummond MF (1992) Cost of illness studies: a major headache? Pharmaco Econ 2:1–4
Brown GC, Brown MM, Sharma S, Brown HC (1998) Patient perceptions of quality-of-life associated with bilateral visual loss. Int Ophthalmol, Vol. 22, No. 5
Weintraub WS (2003) Cardiovascular Health Care Economics. Humana Press Inc, Totowa New Jersey
Insinga RP, Laessig RH, Hoffman GL. (2002) Newborn screening with tandem mass spectrometry: examining its cost-effectiveness in the Wisconsin Newborn Screening Panel. J Pediatr 141:524–531
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer-Verlag/Wien
About this chapter
Cite this chapter
Walter, E., Brennig, C., Schöllbauer, V. (2011). How to save money: congenital CMV infection and the economy. In: Halwachs-Baumann, G. (eds) Congenital Cytomegalovirus Infection. Springer, Vienna. https://doi.org/10.1007/978-3-7091-0208-4_7
Download citation
DOI: https://doi.org/10.1007/978-3-7091-0208-4_7
Publisher Name: Springer, Vienna
Print ISBN: 978-3-7091-0207-7
Online ISBN: 978-3-7091-0208-4
eBook Packages: MedicineMedicine (R0)