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Desmoid-Aggressive Fibromatosis

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Radiation Therapy of Benign Diseases

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Following surgical excision alone, local recurrences occur in 27–57 percent of cases of desmoid — aggressive fibromatosis. Radiation therapy in doses of 5000–6000 rad decreases local recurrence rates. Normal tissue tolerance may be limiting for the total dose of external beam radiation; therefore either post-operative brachytherapy or brachytherapy following external beam may be used. Regression rates may occur from eight months to two years following treatment. Desmoid — aggressive fibromatosis may occur in association with Gardner’s syndrome and pregnancy. A seventy percent local control rate has been reported with external radiation. In the national survey eighty-two percent of radiation oncologists would treat desmoid — aggressive fibromatosis.

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Author information

Authors and Affiliations

  1. The Johns Hopkins Hospital, 21205, Baltimore, MD, USA

    Stanley E. Order MD, ScD, FACR (Director Radiation Oncology)

  2. School of Medicine, Stanford University, 94305, Stanford, CA, USA

    Sarah S. Donaldson MD, FACR (Professor of Radiation Oncology)

Authors
  1. Stanley E. Order MD, ScD, FACR
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  2. Sarah S. Donaldson MD, FACR
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© 1990 Springer-Verlag Berlin Heidelberg

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Order, S.E., Donaldson, S.S. (1990). Desmoid-Aggressive Fibromatosis. In: Radiation Therapy of Benign Diseases. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97160-0_4

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  • DOI: https://doi.org/10.1007/978-3-642-97160-0_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-97162-4

  • Online ISBN: 978-3-642-97160-0

  • eBook Packages: Springer Book Archive

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