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Pathology of Human Cytomegalovirus Infection

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Molecular Aspects of Human Cytomegalovirus Diseases

Part of the book series: Frontiers of Virology ((FRVIROLOGY,volume 2))

Summary

Cytomegalovirus (CMV) produces widely variable pathologic change in infected tissues, whether in the context of acquired immunodeficiency syndrome (AIDS) or another form of immunosuppression, e.g., that noted after organ or bone marrow transplantation. Characteristic cytomegalic cells may be present with minimal or absent inflammatory response in a given organ, or there may be extensive associated inflammation and necrosis with clinically significant dysfunction. This chapter discusses and illustrates the histologic manifestations of CMV infection in the context of their clinical presentation, and complements other chapters that discuss molecular mechanisms of CMV pathogenesis and neuropathogenesis.

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Author notes

  1. Dr. Jorge A. Ferreiro

    Present address: Dept. of Pathology, Mayo Clinic, Rochester, MN, USA

Authors and Affiliations

  1. Department of Pathology, Los Angeles Medical Center, University of California, CHS Room 18-170, Los Angeles, CA, 90024-1732, USA

    Harry V. Vinters & Dr. Jorge A. Ferreiro

  2. Brain Research Institute, Los Angeles Medical Center, University of California, CHS Room 18-170, Los Angeles, CA, 90024-1732, USA

    Harry V. Vinters

Authors
  1. Harry V. Vinters
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  2. Dr. Jorge A. Ferreiro
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Editors and Affiliations

  1. Department of Molecular Virology, Faculty of Medicine, Hebrew University of Jerusalem, POB 1172, 910010, Jerusalem, Israel

    Yechiel Becker

  2. Institut für Medizinische Virologie, Universität Heidelberg, Im Neuenheimer Feld 324, W-6900, Heidelberg, Germany

    Gholamreza Darai

  3. Lineberger Comprehensive Cancer Research Center, The University of North Carolina, CB # 7259, Rm. 117, Lineberger Building, 27599-7295, Chapel Hill, NC, USA

    Eng-Shang Huang Ph. D.

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© 1993 Springer-Verlag Berlin Heidelberg

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Vinters, H.V., Ferreiro, J.A. (1993). Pathology of Human Cytomegalovirus Infection. In: Becker, Y., Darai, G., Huang, ES. (eds) Molecular Aspects of Human Cytomegalovirus Diseases. Frontiers of Virology, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-84850-6_2

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  • DOI: https://doi.org/10.1007/978-3-642-84850-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

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  • Online ISBN: 978-3-642-84850-6

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