Abstract
Small collections of neuroepithelial cells are distributed widely throughout the body. When they are identifible grossly, they are called paraganglia. Those which do not secrete catecholamines, and thus are non-chromaffin, are related to the parasympathetic nervous system. Tumors which develop from these paraganglia are most frequently found in the temporal bone or the cervical region. The term “chemodectoma” has been applied to these tumors because of their lcoation in the vicinity of the carotid body, which is known chemoreceptor sensitive to pH, and concentrations of oxygen and carbon dioxide. Since only the tumors which arise in the vicinity of the aortic body or carotid body can be considered chemodectomas, the more general term, non-chromaffin paraganglioma, is preferred. However, much of the literature concerning these tumors uses “chemodectoma” in a broad sense, and the following discussion will use this term as synonymous with non-chromaffin paraganglioma.
Keywords
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Alford BR, Guilford FR (1953) A comprehensive study of tumors of glomus jugulare. Brain 76: 576
Batsakis JG (1979) Paragangliomas of the head and neck. In: Tumors of the head and neck, 2nd edn. Williams and Wilkins Company, Baltimore, pp369–380
Brammer RE, Graham MD, Kemink JL (1984) Glomus tumors of the temporal bone: Contemporary evaluation and therapy. Otolaryngologic Clinics of North America 17: 499–512
Capps FCW (1957) Tumours of the glomus jugulare or tympanic body. J Facul Radiol 8: 312–324
Chambers RG, Mahoney WD (1968) Carotid body tumors. Am J Surg 115: 554–558
Cole JM (1977) Glomus jugulare tumor. Laryngoscope 87: 1244–1258
Cole JM (1979) Panel discussion: Glomus jugulare tumors of the temporal bone. Radiation of glomus tumors of the temporal bone. Laryngoscope 89:1623
Conley J J (1965) The carotid body tumor: A review of 29 cases. Arch Otolaryngol 81:187–193
Cummings BJ, Beale FA, Garrett PG, Harwood AR, Keane TJ, Payne DG, Rider WD (1984) The treatment of glomus tumors in the temporal bone by megavoltage radiation. Cancer 53: 2635–2640
Dent TL, Thompson NW, Fry WJ (1976) Carotid body tumors. Surg 80: 365–372
Dickens WJ, Million RR, Cassisi NJ, Singleton GT (1982) Chemodectomas arising in temporal bone structures. Laryngoscope 92:188–191
Duke WW, Boshell BR, Soteres P et al. (1964) A norepinephrine-secreting glomus jugulare tumor presenting as a pheochromocytoma. Ann Int Med 60: 1040–1047
Farr HW (1980) Carotid body tumors: A 40-year study. CA-A Cancer Journal for Clinicians 30: 260–265
Grufferman S. Gillman MW, Pasternek LR, Peterson CL, Young WG (1980) Familial carotid body tumors: Case report and epidemiologic review. Cancer 46: 2116–2122
Guild SR (1941) Anat Rec 79: 28
Guild SR (1953) Ann Otol, St. Louis 62: 1045
Hatfield PM, James AE, Schulz MD (1972) Chemodectomas of the glomus jugulare. Cancer 30: 1164–1668
Hudgins PT (1972) Radiotherapy for extensive glomus jugulare tumors. Radiol 103: 427–429
Jackson AW, Koshiba R (1974) Treatment of glomus jugulare tumors by radiotherapy. Proc R Soc Med 67: 9–12
Javid H, Chawla SK, Dye WS et al. (1976) Carotid body tumor. Arch Surg 111: 344–347
Kim JA, Elkon D, Lim ML, Constable WC (1980) Optimum dose of radiotherapy for chemodectomas of the middle ear. Int J Rad Oncol Biol Phys 6: 815–819
Krause W (1878) Zbl Med Wiss 16: 737
Krupski WC, Effeney DJ, Ehrenfeld WK, Stoney RJ (1982) Cervical chemodectoma. Technical considerations and mangemenl options. Am J Surg 144: 215–220
Lack EE, Cubilla AL, Woodruff JM, Farr HW (1977) Paragangliomas of the head and neck region. Cancer 39: 397–409
Levit SA, Sheps SG, Espinosa RE et al. (1976) Cathecholamine-secreting paraganglioma of glomus-jugulare region resembling phenchromocytoma. New Engl J Med 281: 805–811
Lybeert MLM, van Andel JG, Eijkenboom WMH, de Jong PC, Kengt P (1984) Radiotherapy of paragangliomas. Clin Otolaryngol 9:105–109
Martin CE, Rosenfeld L, McSwain B (1973) Carotid body tumors. A 16-year followup of seven malignant cases. Southern Med J 66: 1236–1243
Maruyama Y (1972) Radiotherapy of tympanojugular chemodectomas. Radiol 105: 659–663
McCabe B, Fletcher M (1979) Selection of therapy of glomus jugulare tumors. Arch Otolaryngol 89:182–185
McGuirt WF, Harker LA (1975) Carotid body tumors. Arch Otolaryngol 101: 58–62
Million RR, Cassisi NJ (1984) Chemodectomas (Glomus Body Tumors). In: Management of Head and Neck Cancer, A Multi-disciplinary Approach. J B Lippincott Company, Philadelphia, pp 567–578
Newman H, Rowe JF Jr, Phillips TL (1973) Radiation therapy of the glomus jugulare tumor. AJR 18: 663–669
Reddy EK, Mansfield CM, Hartman GV (1983) Chemodectoma of glomus jugulare. Cancer 52: 337–340
Rosai J (1981) Ackerman’s surgical pathology 6th edn. The C V Mosby Company, St. Louis, pp697–727
Rosenwasser H (1951) Arch Otolaryng 54: 453
Rosenwasser H (1958) Metastasis from glomus jugulare tumors. AMA Archives Otolaryngol 67:197–203
Saldana MJ, Salem LE, Travezan R (1973) High altitude hypoxia and chemodectomas. Human Pathol 4: 251–263
Shamblin WR, ReMine WH, Sheps SG, Harrison EG Jr (1971) Carotid body tumor (chemodectoma). Clinicopathologic analysis of ninety cases. Am J Surg 122: 732–739
Simko TG, Griffin TW, Gerdes AJ, Parker RG, Tesh DW, Taylor W, Blasko JC (1978) The role of radiation therapy in the treatment of glomus jugulare tumors. Cancer 42: 104–106
Spector GJ, Campagno J, Perez CA, Maisel RH, Ogura JH (1975) Glomus jugulare tumors: Effects of radiotherapy. Cancer 35:1316–1321
Spector GJ, Fierstein J, Ogura JH (1976) A comparison of therapeutic modalities of glomus tumors in the temporal bone. Laryngoscope 86: 690–696
Suit HD, Gallagher HS (1964) Intact tumor cells in irradiated tissue. Arch Pathol 78: 648
Tidwell TJ, Montague ED (1975) Chemodectomas involving the temporal bone. Radiol 116: 147–149
Valentin G (1840) Arch Anta Physiol LPZ: 287
Van Asperen de Boer FRS, Terpstra JL, Vink M (1981) Diagnosis, treatment and operative complications of carotid body tumors. Br J Surg 68: 433–438
Van Haller, cited by Dickinson AM, Traver CA (1945) Carotid body tumors. Review of the literature with report of two cases. Am J Surg 69: 9–11
Wang CC, Doppke K (1976) Osteoradionecrosis of the temporal bone - Consideration of nominal standard dose. Rad Oncol Biol Phys 1: 881–883
Wang CC (1980) What is the optimum dose of radiation therapy for glomus jugulare? Int J Radiat Oncol Biol Phys 6: 945–946
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Olson, L.E., Cox, J.D. (1989). Chemodectomas. In: Laramore, G.E. (eds) Radiation Therapy of Head and Neck Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83501-8_12
Download citation
DOI: https://doi.org/10.1007/978-3-642-83501-8_12
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-83503-2
Online ISBN: 978-3-642-83501-8
eBook Packages: Springer Book Archive