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Ultrastructure of Non-Hodgkin’s Lymphomas

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Part of the book series: Handbuch der Speziellen Pathologischen Anatomie und Histologie ((1690,volume 1 / 3 / B))

Abstract

The previous development of ultrastructural studies of non-Hodgkin’s lymphomas can be divided into three phases. The first phase was stimulated by the idea that it might be possible to find ultrastructural features that are specific to malignant cells. It appeared that it might also be possible to gain insight into the genesis of tumors. This hope has not been fulfilled, as Bernhard anticipated as early as 1961.

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References

  • Ada, G.L., Nossal, G.J.V., Austin, C.M.: Antigens in immunity. V. The ability of cells in lymphoid follicles to recognize foreignness. Aust. J. exp. Biol. med. Sci. 42, 331–346 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Akasaka, K.: Proliferative diseases of the RES presenting a leukemic blood picture: Phase-contrast and electron microscopic studies. Recent Adv. RES Res. 12, 183–213 (1973).

    Google Scholar 

  • Anday, G.J., Goodman, J.R., Tishkoff, G.H.: An unusual cytoplasmic ribosomal structure in pathologic lymphocytes. Blood 41, 439–449 (1973).

    PubMed  CAS  Google Scholar 

  • Anderson, D.R.: Ultrastructure of normal and leukemic leukocytes in human peripheral blood. J. Ultrastruct. Res. Suppl. 9 (1966).

    Google Scholar 

  • Argani, I., Kipkie, G.F.: The cellular origin of macroglobulins. A study of the protein-secreting cells in Waldenström’s disease. Lab. Invest. 14, 720–728 (1965).

    PubMed  CAS  Google Scholar 

  • Avrameas, S., Leduc, E.H.: Detection of simultaneous antibody synthesis in plasma cells and specialized lymphocytes in rabbit lymph nodes. J. exp. Med. 131, 1137–1168 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Barcos, M.P., Lukes, R.J.: Malignant lymphoma of convoluted lymphocytes: A new entity of possible T-cell type. In: Conflicts in Childhood Cancer. An Evaluation of Current Management, Vol. 4, pp. 147–178. Sinks, L.F., Godden, J.O., Eds. New York: Liss 1975.

    Google Scholar 

  • Barka, T., Anderson, P.J.: Histochemistry. Theory, Practice, and Bibliography. New York-Evans-ton-London: Harper & Row 1963.

    Google Scholar 

  • Beachey, E.H., Hashimoto, K., Burkett, L.L.: Histiocytic leukemia: ultrastructure and phagocytic capacity of hairy cells. [Abstr.] Clin. Res. 17, 530 (1969).

    Google Scholar 

  • Bedoya, V., Grimley, P.M., Rabson, A.S.: Ultrastructural evidence of in vitro interaction among Burkitt lymphoma cells: Possible relevance to the “phagocytic” activity of starry sky histiocytes in vivo. Cancer Res. 29, 753–762 (1969).

    PubMed  CAS  Google Scholar 

  • Berard, C., O’Conor, G.T., Thomas, L.B., Torloni, H.: Histopathological definition of Burkitt’s tumour. Bull. Wld Hlth Org. 40, 601–607 (1969).

    Google Scholar 

  • Bernard, J., Bessis, M., Soulier, J.P., Thiéry, J.P.: Étude au microscope électronique d’une leucémie lymphoide avec cristaux intra-cytoplasmiques. Rev. Hémat. 14, 227–237 (1959).

    PubMed  CAS  Google Scholar 

  • Bernhard, W.: Elektronenmikroskopischer Beitrag zum Studium der Kanzerisierung und der malignen Zustände der Zelle. Verh. dtsch. Ges. Path. 45, 8–37 (1961).

    CAS  Google Scholar 

  • Bernhard, W.: Fine structure of Burkitt’s lymphoma. In: Burkitt’s Lymphoma, pp. 103–117. Burkitt, D.P., Wright, D.H., Eds. Edinburgh-London: Livingstone 1970.

    Google Scholar 

  • Bernhard, W., Leplus, R.: Structure fine du ganglion humain normal et malin. Oxford: Pergamon Press [usw.] 1964.

    Google Scholar 

  • Bessis, M.: Études au microscope électronique des leucocytes normaux et leucémiques. Acta Un. int. Cancer 7, 646–659 (1951).

    CAS  Google Scholar 

  • Bessis, M.C.: Ultrastructure of lymphoid and plasma cells in relation to globulin and antibody formation. Lab. Invest. 10, 1040–1067 (1961).

    PubMed  CAS  Google Scholar 

  • Bessis, M.: Living Blood Cells and Their Ultrastructure. Berlin-Heidelberg-New York: Springer 1973.

    Google Scholar 

  • Bonneau, H., Cesarini, J.-P.: Étude ultrastructurale d’un cas de mycosis fongoïde. Bull. Soc. franç. Derm. Syph. 74, 612–617 (1967)

    PubMed  CAS  Google Scholar 

  • Bosman, F.T., van Vloten, W.A.: Sézary’s syndrome: A cytogenetic, cytophotometric and autoradiographic study. J. Path. 118, 49–57 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Brittinger, G., Augener, W., Bremer, K., Cohnen, G., Dabag, S., Fischer, K., König, E., Meusers, P.: Der Lymphozyt bei der chronischen lymphatischen Leukämie. Blut 30, 293–308 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Brouet, J.-C., Flandrin, G., Sasportes, M., Preud’Homme, J.-L., Seligmann, M.: Chronic lymphocytic leukaemia of T-cell origin. Immunological and clinical evaluation in eleven patients. Lancet 1975, II, pp. 890–893.

    Article  Google Scholar 

  • Brownlee, T.R., Murad, T.M.: Ultrastructure of mycosis fungoides. Cancer (Philad.) 26, 686–698 (1970).

    Article  CAS  Google Scholar 

  • Brunning, R.D., Parkin, J.: Ultrastructural studies of parallel tubular arrays in human lymphocytes. Amer. J. Path. 78, 59–70 (1975).

    PubMed  CAS  Google Scholar 

  • Burke, J. S., Mackay, B., Rappaport, H.: Hairy cell leukemia (leukemic reticuloendotheliosis). II. Ultrastructure of the spleen. Cancer (Philad.) 37, 2267–2274 (1976).

    Article  CAS  Google Scholar 

  • Carr, I.: The ultrastructure of the abnormal reticulum cells in Hodgkin’s disease. J. Path. 115, 45–50 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Catovsky, D.: T-cell origin of acid-phosphatase-positive lymphoblasts. Lancet 1975, II, pp. 327–328.

    Article  Google Scholar 

  • Catovsky, D., Frisch, B., van Noorden, S.: B, T and ‘null’ cell leukaemias. Electron cytochemistry and surface morphology. Blood Cells 1, 115–124 (1975).

    Google Scholar 

  • Cawley, J.C., Barker, C.R., Britchford, R.D., Smith, J.L.: Intracellular IgA immunoglobulin crystals in chronic lymphocytic leukaemia. Clin. exp. Immunol. 13, 407–416 (1973).

    PubMed  CAS  Google Scholar 

  • Cawley, J.C., Emmines, J., Goldstone, A.H., Hamblin, T., Hough, D., Smith, J.L.: Distinctive cytoplasmic inclusions in chronic lymphocytic leukaemia. Europ. J. Cancer 11, 91–92 (1975).

    Article  CAS  Google Scholar 

  • Cawley, J.C., Smith, J., Goldstone, A.H., Emmines, J., Hamblin, J., Hough, L.: IgA and IgM cytoplastic inclusions in a series of cases of chronic lymphocytic leukaemia. Clin. exp. Immunol. 23, 78–82 (1976).

    PubMed  CAS  Google Scholar 

  • Chandra, S.: Undulating tubules associated with endoplasmic reticulum in pathologic tissues. Lab. Invest. 18, 422–428 (1968).

    PubMed  CAS  Google Scholar 

  • Chelloul, N., Daumas-Duport, C., Bonvallet, D., Briere, J., Vorhauer-Atlan, W., Bernuau, D.: Pathologie ganglionnaire au cours des dermatoses avec cellules de Sézary circulantes. Biomedicine 24, 62–77 (1976).

    PubMed  CAS  Google Scholar 

  • Clark, C., Rydell, R.E., Kaplan, M.E.: Frequent association of IgMA with crystalline inclusions in chronic lymphatic leukemic lymphocytes. New Engl. J. Med. 289, 113–117 (1973).

    Article  PubMed  CAS  Google Scholar 

  • Cohnen, G.: T- und B-Lymphozyten bei chronischer lymphatischer Leukämie und Lymphogranulomatose. Elektronenmikroskopische und immunologische Untersuchungen. Veröff. Path. H. 97. Stuttgart: G. Fischer 1975.

    Google Scholar 

  • Cohnen, G., Fischer, K., Ludwig, H., Brittinger, G.: Rasterelektronenmikroskopische Beobachtungen an Blutlymphozyten von Normalpersonen und Patienten mit chronischer lymphatischer Leukämie (Vortrag). Blut 31, 180 (1975).

    Google Scholar 

  • Daniel, M.T., Flandrin, G.: Fine structure of abnormal cells in hairy cell (tricholeukocytic) leukemia with special reference to their in vitro phagocytic capacity. Lab. Invest. 30, 1–8 (1974).

    PubMed  CAS  Google Scholar 

  • Debusscher, L., Bernheim, J.L., Collard-Rongé, E., Govaerts, A., Hooghe, R., Lejeune, F.J., Zeicher, M., Stryckmans, P.A.: Hairy cell leukemia: Functional, immunologic, kinetic, and ultrastructural characterization. Blood 46, 495–507 (1975).

    PubMed  CAS  Google Scholar 

  • Diebold, J., Reynes, M., Kalifat, R., Tricot, G.: Les inclusions intranucléaires de la maladie de Waldenström. Signification biologique et valeur diagnostique. Nouv. Presse méd. 3, 1067–1070 (1974).

    PubMed  CAS  Google Scholar 

  • Diebold, J., Reynes, M., Kalifat, R., Tricot, G.: Les expressions morphologiques de la maladie de Waldenström. Sem. Hôp. Paris 51, 2927–2934 (1975).

    PubMed  CAS  Google Scholar 

  • Djaldetti, M., Landau, M., Mandel, E.M., Har-Zaav, L., Lewinski, U.: Electron microscopic study of lymphosarcoma cell leukemia. Blut 29, 210–215 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Dorfman, R.F.: Diagnosis of Burkitt’s tumor in the United States. Cancer 21, 563–574 (1968).

    Article  PubMed  CAS  Google Scholar 

  • Douglas, S.D., Borjeson, J., Chessin, L.N.: Studies on human lymphocytes in vitro. IV. Comparative fine structural features of the established Burkitt lymphoma cell lines AL-1, EB-2 and phytomitogen-transformed lymphocytes. J. Immunol. 99, 340–346 (1967).

    PubMed  CAS  Google Scholar 

  • Douglas, S.D., Cohnen, G., Brittinger, G.: Ultrastructural comparison between phytomitogen transformed normal and chronic lymphocytic leukemia lymphocytes. J. Ultrastruct. Res. 44, 11–26 (1973).

    Article  PubMed  CAS  Google Scholar 

  • Douglas, S.D., Cohnen, G., König, E., Brittinger, G., Fischer, K., Bremer, K.: Electron microscopic and biochemical studies on lysosomes and lysosomal enzymes in “resting” and phytohemagglutinin (PHA) stimulated lymphocytes from patients with chronic lymphatic leukemia (CLL). In: Leukämie, pp. 29–35. Gross, R., van de Loo, J., Eds. Berlin-Heidelberg-New York: Springer 1972.

    Chapter  Google Scholar 

  • Edelson, R.L., Kirkpatrick, C.H., Shevach, E.M., Schein, P.S., Smith, R.W., Green, I., Lutzner, M.: Preferential cutaneous infiltration by neoplastic thymus-derived lymphocytes. Morphologic and functional studies. Ann. intern. Med. 80, 685–692 (1974).

    PubMed  CAS  Google Scholar 

  • Edelson, R.L., Lutzner, M.A., Kirkpatrick, C.H., Shevach, E.M., Green, I.: Morphologic and functional properties of the atypical T lymphocytes of the Sezary syndrome. Mayo Clin. Proc. 49, 558–566 (1974).

    PubMed  CAS  Google Scholar 

  • Epstein, M.A.: Histogenesis of the Burkitt lymphoma. In: Treatment of Burkitt’s Tumour. UICC Monograph Series, Vol. 8, pp. 29–33. Burchenal, J.H., Burkitt, D.P., Eds. Berlin-Heidelberg-New York: Springer 1967.

    Google Scholar 

  • Epstein, M.A., Achong, B.G.: Fine structural organization of human lymphoblasts of a tissue culture strain (EBl) from Burkitt’s lymphoma. J. nat. Cancer Inst. 34, 241–253 (1965).

    PubMed  CAS  Google Scholar 

  • Epstein, M.A., Achong, B.G.: The fine structure of cultured Burkitt lymphoblasts of established in vitro strains. In: Burkitt’s Lymphoma, pp. 118–133. Burkitt, D.P., Wright, D.H., Eds. Edinburgh-London: Livingstone 1970.

    Google Scholar 

  • Epstein, M.A., Achong, B.G., Barr, Y.M.: Virus particles in cultured lymphoblasts from Burkitt’s lymphoma. Lancet 1964, I, pp. 702–703.

    Article  Google Scholar 

  • Epstein, M.A., Achong, B.G., Barr, Y.M., Zajac, B., Henle, G., Henle, W.: Morphological and virological investigations on cultured Burkitt tumor lymphoblasts (strain Raji). J. nat. Cancer Inst. 37, 547–559 (1966).

    PubMed  CAS  Google Scholar 

  • Fagraeus, A.: Antibody production in relation to the development of plasma cells. In vivo and in vitro experiments. Acta med. scand. 130, Suppl. 204 (1948).

    Google Scholar 

  • Flad, H.-D., Huber, C., Bremer, K., Menne, H.-D., Huber, H.: Impaired recirculation of B lymphocytes in chronic lymphocytic leukemia. Europ. J. Immunol. 3, 688–693 (1973).

    Article  CAS  Google Scholar 

  • Flandrin, G., Daniel, M.T.: La leucémia à tricholeucocytes (hairy cell leukemia). Une variété rare et mal connue d’hématopathic maligne. Nouv. Presse méd. 3, 581–586 (1974).

    PubMed  CAS  Google Scholar 

  • Flaxman, B.A., Zelazny, G., van Scott, E.J.: Nonspecificity of characteristic cells in mycosis fungoides. Arch. Derm. 104, 141–147 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Foa, R., Foa, C., Muratore, R.: Aspects particuliers du réticulum endoplasmique dans trois cas de leucose et un cas de réticulosarcome. C.R. Soc. Biol. (Paris) 164, 1048–1054 (1970).

    CAS  Google Scholar 

  • Ghadially, F.N., Skinnider, L.F.: Ultrastructure of hairy cell leukemia. Cancer (Philad.) 29, 444–452 (1972).

    Article  CAS  Google Scholar 

  • Glick, A.D., Leech, J.H., Waldron, J.A., Flexner, J.M., Horn, R.G., Collins, R.D.: Malignant lymphomas of follicular center cell origin in man. II. Ultrastructural and cytochemical studies. J. nat. Cancer Inst. 54, 23–36 (1975).

    PubMed  CAS  Google Scholar 

  • Golomb, H.M., Braylan, R., Polliack, A.: ‘Hairy’ cell leukaemia (Leukaemic reticuloendotheliosis): A scanning electron microscopic study of eight cases. Brit. J. Haemat. 29, 455–460 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Gomez Orbaneja, J., Sanchez Yus, E., Diaz-Flores, L., Simon Huarte, P.: Cytology of the mycosis fungoides and the Sézary syndrome. Correlation between light and electron microscopy. Brit. J. Derm. 87, 96–105 (1972).

    Article  Google Scholar 

  • Goos, M., Kaiserling, E., Lennert, K.: Mycosis fungoides: model for T-lymphocyte homing to the skin? Brit. J. Derm. 94, 221–222 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Griffin, E.R., Wright, D.H., Bell, T.M., Ross, M.G.R.: Demonstration of virus particles in biopsy material from cases of Burkitt tumor. Europ. J. Cancer 2, 235–358 (1966).

    Google Scholar 

  • Haak, H.L., de Man, J.C.H., Hijmans, W., Knapp, W., Speck, B.: Further evidence for the lymphocytic nature of leukaemic reticuloendotheliosis (hairy-cell-leukaemia). Brit. J. Haemat. 27, 31–38 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Haegert, D.G., Cawley, J.C., Collins, R.D., Flemans, R.J., Smith, J.L.: Leukaemic reticuloendotheliosis: A morphological and immunological study of four cases. J. clin. Path. 27, 967–972 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Hamburg, A., Brynes, R.K., Reese, C., Golomb, H.M.: Human cord blood lymphocytes. Ultra-structural and immunologic surface marker characteristics; a comparison with B- and T-cell lymphomas. Lab. Invest. 34, 207–215 (1976).

    PubMed  CAS  Google Scholar 

  • Hanna, Jr., M.G., Szakal, A.K., Tyndall, R.L.: Histoproliferative effect of Rauscher leukemia virus on lymphatic tissue: Histological and ultrastructural studies of germinal centers and their relation to leukemogenesis. Cancer Res. 30, 1748–1763 (1970).

    PubMed  Google Scholar 

  • Henry, K.: Electron microscopy in the non-Hodgkin’s lymphomata. Brit. J. Cancer 31, Suppl. II, 73–93 (1975).

    Google Scholar 

  • Huhn, D.: Feinstruktur peripherer Lymphozyten bei chronischer lymphatischer Leukämie. Dtsch. med. Wschr. 95, 897–901 (1970).

    Article  PubMed  CAS  Google Scholar 

  • Huhn, D., Dobbelstein, H., Engelhardt, D.: Sézary-Syndrom. Blut 25, 352–363 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Huhn, D., Rodt, H., Thiel, E., Grosse-Wilde, H., Fink, U., Theml, H., Jäger, G., Steidle, C., Thierfelder, S.: T-Zell-Leukämien des Erwachsenen. Blut 33, 141–160 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Huhn, D., Thiel, E., Rodt, H.: Immunglobulin-Ablagerungen in Lymphadenose-Zellen. Klin. Wschr. 53, 317–320 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Hurez, D., Flandrin, G., Preud’Homme, J.L., Seligmann, M.: Unreleased intracellular monoclonal macroglobulin in chronic lymphocytic leukaemia. Clin. exp. Immunol. 10, 223–234 (1972).

    PubMed  CAS  Google Scholar 

  • Insel, R.A., Melewicz, F.M., La Via, M.F., Balch, C.M.: Morphology, surface markers, and in vitro responses of a human leukemic T cell. Clin. Immunol. Immunopath. 4, 382–391 (1975).

    Article  CAS  Google Scholar 

  • Ito, S.: Study on the in vitro Rieder cell. Scand. J. Haemat. 12, 355–365 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Jaffe, E.S., Shevach, E.M., Frank, M.M., Berard, C.W., Green, I.: Nodular lymphoma— evidence for origin from follicular B lymphocytes. New Engl. J. Med. 290, 813–819 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Jeffree, G.M.: Enzymes of round cell tumours in bone and soft tissue: A histochemical survey. J. Path. 113, 101–115 (1974).

    Article  PubMed  CAS  Google Scholar 

  • Kaiserling, E.: Verzweigte tubuläre Cytoplasmaeinschlüsse im menschlichen Lymphknoten. Beitr. Path. 147, 237–248 (1972).

    Article  CAS  Google Scholar 

  • Kaiserling, E.: Feinstrukturelle Befunde bei Non-Hodgkin-Lymphomen. Habil. Schrift, Kiel 1975.

    Google Scholar 

  • Kaiserling, E.: Elektronenmikroskopische Befunde bei Non-Hodgkin-Lymphomen. In: Maligne Lymphome und monoklonale Gammopathien. Hämatologie und Bluttransfusion, Bd. 18, pp. 185–198. Löffler, H., Ed. München: Lehmanns 1976.

    Google Scholar 

  • Kaiserling, E.: Non-Hodgkin-Lymphome. Ultrastruktur und Cytogenese. Veröff. Path., Heft 105. Stuttgart: G. Fischer 1977

    Google Scholar 

  • Kaiserling, E., Lennert, K.: Die interdigitierende Reticulumzelle im menschlichen Lymphknoten. Eine spezifische Zelle der thymusabhängigen Region. Virchows Arch. B16, 51–61 (1974).

    Google Scholar 

  • Kaiserling, E., Stein, H., Lennert, K.: IgM-producing malignant lymphomas without macroglobulinemia. Morphological and immunochemical findings. Virchows Arch. B 14, 1–18 (1973).

    CAS  Google Scholar 

  • Katayama, I., Li, C.Y., Yam, L.T.: Ultrastructural characteristics of the “hairy cells” of leukemic reticuloendotheliosis. Amer. J. Path. 67, 361–370 (1972a).

    PubMed  CAS  Google Scholar 

  • Katayama, I., Li, C.Y., Yam, L.T.: Ultrastructural characteristics of the “hairy cells” of leukemic reticuloendotheliosis. Amer. J. Path. 67, 361–370 (1972b).

    PubMed  CAS  Google Scholar 

  • Katayama, I., Nagy, G.K., Balogh, Jr., K.: Light microscopic identification of the ribosome-lamella complex in “hairy cells” of leukemic reticuloendotheliosis. Cancer (Philad.) 32, 843–846 (1973).

    Article  CAS  Google Scholar 

  • Katayama, I., Uehara, H., Gleser, R.A., Weintraub, L.: The value of electron microscopy in the diagnosis of Burkitt’s lymphoma. Amer. J. clin. Path. 61, 540–548 (1974).

    CAS  Google Scholar 

  • Kim, H., Heller, P., Rappaport, H.: Monoclonal gammopathies associated with lymphoproliferative disorders: A morphologic study. Amer. J. clin. Path. 59, 282–294 (1973).

    CAS  Google Scholar 

  • King, G.W., Hurtubise, P.E., Sagone, Jr., A.L., LoBuglio, A.F., Metz, E.N.: Leukemic reticuloendotheliosis. A study of the origin of the malignant cell. Amer. J. Med. 59, 411–416 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Klippel, J.H., Decker, J.L., Grimley, P.M., Evans, A.S., Rothfield, N.F.: Epstein-Barr virus antibody and lymphocyte tubuloreticular structures in systemic lupus erythematosus. Lancet 1973, II, pp. 1057–1058.

    Article  Google Scholar 

  • Knapp, W., Schuit, H.R.E., Bolhuis, R.L.H., Hijmans, W.: Surface immunoglobulins in chronic lymphatic leukaemia, macroglobulinaemia and myelomatosis. Clin. exp. Immunol. 16, 541–552 (1974).

    Google Scholar 

  • Kojima, M.: Cytopathological study on lymph node, especially reference to germinal center. [Jap.] Nippon Byöri Gakkai Kaishi (Trans. Soc. Path. Jap.) 58, 3–28 (1969).

    Google Scholar 

  • Kojima, M., Imai, Y., Mori, N.: A concept of follicular lymphoma. A proposal for the existence of a neoplasm originating from the germinal center. In: Malignant Diseases of the Hematopoietic System. GANN Monograph on Cancer Research, No. 15, pp. 195–207. Akazaki, K., Rappaport, H., Berard, C.W., Bennett, J.M., Ishikawa, E., Eds. Baltimore-London-Tokyo: University of Tokyo Press 1973.

    Google Scholar 

  • Krüger, G., O’Conor, G.T.: Epidemiologic and immunologic considerations on the pathogenesis of Burkitt’s tumor. In: Current Problems in the Epidemiology of Cancer and Lymphomas. Recent Results in Cancer Research, Vol. 39, pp. 211–224. Grundmann, E., Tulinius, H., Eds. Berlin-Heidelberg-New York: Springer 1972.

    Chapter  Google Scholar 

  • Kuhn, C.: Nuclear bodies and intranuclear globulin inclusions in Waldenström’s macroglobulinemia. Lab. Invest. 17, 404–415 (1967).

    PubMed  CAS  Google Scholar 

  • Labaze, J.J., Moscovic, E.A., Pham, T.D., Azar, H.A.: Histological and ultrastructural findings in a case of the Sézary syndrome. J. clin. Path. 25, 312–319 (1972).

    Article  PubMed  CAS  Google Scholar 

  • Laszlo, J., Gerber, H.J., Sommer, J.R.: Composition and structure of cytoplasmic globules in leukemic lymphocytes. Blood 29, 77–86 (1967).

    PubMed  CAS  Google Scholar 

  • van Leeuwen, A.W.F.M., Meijer, C.J.L.M., de Man, J.C.H.: T-cell membrane characteristics of mycosis cells’ in the skin and lymph node. J. invest. Derm. 65, 367–369 (1975).

    Article  PubMed  Google Scholar 

  • van Leeuwen, A.W.F.M., Meijer, C.J.L.M., van Vloten, W.A., Scheffer, E., de Man, J.C.H.: Further evidence for the T-cell nature of the atypical mononuclear cells in mycosis fungoides. Virchows Arch. B 21, 179–187 (1976).

    Google Scholar 

  • Lennert, K.: Follicular lymphoma. A tumor of the germinal centers. In: Malignant Diseases of the Hematopoietic System. GANN Monograph on Cancer Research, Vol. 15, pp. 217–231. Akazaki, K., Rappaport, H., Berard, C.W., Bennett, J.M., Ishikawa, E., Eds. Tokyo: University of Tokyo Press 1973.

    Google Scholar 

  • Lennert, K.: Klassifikation und Morphologie der Non-Hodgkin-Lymphome. In: Maligne Lymphome und monoklonale Gammopathien. Hämatologie und Bluttransfusion, Bd. 18, pp. 145–166. Löffler, H., Ed. München: Lehmanns 1976.

    Google Scholar 

  • Lennert, K., Caesar, R., Müller, H.K.: Electron microscopic studies of germinal centers in man. In: Germinal Centers in Immune Responses, pp. 49–59. Cottier, H., Odartchenko, N., Schindler, R., Congdon, C.C., Eds. Berlin-Heidelberg-New York: Springer 1967.

    Google Scholar 

  • Lennert, K., Kaiserling, E., Müller-Hermelink, H.K.: T-associated plasma-cells. [Letter to the Editor.] Lancet 1975, I, pp. 1031–1032.

    Article  Google Scholar 

  • Lennert, K., Kaiserling, E., Müller-Hermelink, H.K.: Malignant lymphomas: Models of differentiation and cooperation of lymphoreticular cells. Paper presented at Cold Spring Harbor Meeting on “Differentiation of Normal and Neoplastic Hematopoietic Cells” in Cold Spring Harbor, New York, USA, Sept. 6–11, 1977. In press.

    Google Scholar 

  • Lennert, K., Niedorf, H.R.: Nachweis von desmosomal verknüpften Reticulumzellen im follikulären Lymphom (Brill Symmers). Virchows Arch. B 4, 148–150 (1969).

    CAS  Google Scholar 

  • Levine, G.D., Dorfman, R.F.: Nodular lymphoma: An ultrastructural study of its relationship to germinal centers and a correlation of light and electron microscopic findings. Cancer (Philad.) 35, 148–164 (1975).

    Article  CAS  Google Scholar 

  • Litovitz, T.L., Lutzner, M.A.: Quantitative measurements of blood lymphocytes from patients with chronic lymphocytic leukemia and the Sézary syndrome. J. nat. Cancer Inst. 53, 75–77 (1974).

    PubMed  CAS  Google Scholar 

  • Löffler, H., Meyhöfer, W., Lange, R.H., Ehlers, G., Remmele, W.: Sézary-Syndrom — eine leukämische Variante der Mykosis fungoides. Dtsch. med. Wschr. 99, 429–434 (1974).

    Article  PubMed  Google Scholar 

  • Löffler, H., Roux, A., Fischer, J., Desaga, J.F., Pralle, H., Graubner, M.: Hairy cell-Leukämie. In: Maligne Lymphome und monoklonale Gammopathien. Hämatologie und Bluttransfusion, Bd. 18, pp. 255–272. Löffler, H., Ed. München: Lehmanns 1976.

    Google Scholar 

  • Lukes, R.J., Butler, J.J., Hicks, E.B.: Natural history of Hodgkin’s disease as related to its pathologic picture. Cancer (Philad.) 19, 317–344 (1966).

    Article  Google Scholar 

  • Lukes, R.J., Collins, R.D.: New approaches to the classification of the lymphomata. Brit. J. Cancer 31, Suppl. II, 1–28 (1975).

    Google Scholar 

  • Lutzner, M.A., Emerit, I., Durepaire, R., Flandrin, G., Grupper, C., Prunieras, M.: Cytogenetic, cytophotometric, and ultrastructural study of large cerebriform cells of the Sézary syndrome and description of a small-cell variant. J. nat. Cancer Inst. 50, 1145–1162 (1973).

    PubMed  CAS  Google Scholar 

  • Lutzner, M.A., Hobbs, J.W., Horvath, P.: Ultrastructure of abnormal cells. In Sezary syndrome, mycosis fungoides, and parapsoriasis en plaque. Arch. Derm. 103, 375–386 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Lutzner, M.A., Jordan, H.W.: The ultrastructure of an abnormal cell in Sézary’s syndrome. Blood 31, 719–726 (1968).

    PubMed  CAS  Google Scholar 

  • de Man, J.C.H., Meiners, W.B.H.: Crystals of protein nature in the cytoplasm of lymphatic cells in a case of lymphoreticular malignancy. Blood 20, 492–500 (1962).

    Google Scholar 

  • de Martino, C., Zamboni, L.: Silver methenamine stain for electron microscopy. J. Ultrastruct. Res. 19, 273–282 (1967).

    Article  PubMed  Google Scholar 

  • McLaughlin, H., Wetherly-Mein, G., Pitcher, C., Hobbs, J.R.: Non-immunoglobulin-bearing ‘B’ lymphocytes in chronic lymphatic leukaemia? Brit. J. Haemat. 25, 7–14 (1973).

    Article  PubMed  CAS  Google Scholar 

  • Mollo, F., Monga, G., Stramignoni, A.: Dark reticular cells in human lymphadenitis and lymphomas. Virchows Arch. B 3, 117–126 (1969).

    CAS  Google Scholar 

  • Mollo, F., Monga, G., Stramignoni, A.: Electron microscopy in morphological classification of human lymphomas. J. submicroscop. Cytol. 3, 105–120 (1971).

    Google Scholar 

  • Moragas, A., Guardia, J., Martinez-Vazquez, J.M., Vilaseca, J., Ferragut, A., Bacardi, R., Tornos, J.: Lymphome nodulaire associé à une macroglobulinémie. Lyon méd. 230, 691–694 (1973).

    Google Scholar 

  • Mori, Y., Lennert, K.: Electron microscopic atlas of lymph node cytology and pathology. Berlin-Heidelberg-New York: Springer 1969.

    Google Scholar 

  • Müller-Hermelink, H.K., Caesar, R.: Elektronenmikroskopische Untersuchung der Keimzentren in menschlichen Tonsillen. Z. Zellforsch. 96, 521–547 (1969).

    Article  PubMed  Google Scholar 

  • Müller-Hermelink, H.K., Kaiserling, E.: Seminar für elektronenmikroskopisch-histochemische Techniken. Verh. dtsch. Ges. Path. 59, 522–527(1975).

    Google Scholar 

  • Müller-Hermelink, H.K., Kaiserling, E., Lennert, K.: Pseudofollikuläre Nester von Plasmazellen (eines besonderen Typs?) in der paracorticalen Pulpa menschlicher Lymphknoten. Virchows Arch. B14, 47–56 (1973).

    Google Scholar 

  • Nies, K.M., Marshall, J., Oberlin, M.A., Halpern, M.S., Brown, J.C.: Chronic lymphocytic leukemia with gamma chain cytoplasmic inclusions. Amer. J. clin. Path. 65, 948–956 (1976).

    CAS  Google Scholar 

  • Orfanos, C., Stüttgen, G.: Elektronenmikroskopische Beobachtungen bei der Mycosis fungoides. Nachweis von cytoplasmatischen „Zelleinschlüssen“. Arch. klin. exp. Derm. 215, 438–460 (1963).

    Article  PubMed  CAS  Google Scholar 

  • Ottó, S., Balogh, I., Jákó, J.: Electron microscopic study of plasma cells in immunoproliferative diseases. Acta morph. Acad. Sci. hung. 22, 331–336 (1974).

    Google Scholar 

  • Padilla, F., Soloff, B.L.: Electron microscopic observations on ‘hairy’ lymphoreticular cells. [Abstr.] Clin. Res. 17, 32 (1969).

    Google Scholar 

  • Padilla, F., Soloff, B.L.: Leukemic reticuloendotheliosis. Electron microscopy of circulating lymphoid cells. Nouv. Rev. franç. Hémat. 11, 547–554 (1971).

    PubMed  CAS  Google Scholar 

  • Paintrand, M., Dantchev, D., Mathé, G.: Electron microscopic aspects of cells in the four subvarieties of acute lymphoid leukemia. In: Recent Results Cancer Res. 43, 71–75. Berlin-Heidelberg-New York: Springer 1973.

    Google Scholar 

  • Pedio, G., Rüttner, J.R., Spycher, M.A., Gut, D.: Virus-bearing plasma cells in peripheral blood of a patient with ‘hairy cell’ leukemia. Acta haemat. (Basel) 54, 297–305 (1975).

    Article  CAS  Google Scholar 

  • Polliack, A., Siegal, F.P., Clarkson, B.D., Fu, S.M., Winchester, R.J., Lampen, N., Siegal, M., DeHarven, E.: A scanning electron microscopy and immunological study of 84 cases of lymphocytic leukaemia and related lymphoproliferative disorders. Scand. J. Haemat. 15, 359–376 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Pope, J.H., Achong, B.G., Epstein, M.A.: Cultivation and fine structure of virus-bearing lymphoblasts from a second New Guinea Burkitt lymphoma: Establishment of sublines with unusual cultural properties. Int. J. Cancer 3, 171–182 (1968).

    Article  PubMed  CAS  Google Scholar 

  • Pope, J.H., Achong, B.G., Epstein, M.A., Biddulph, J.: Burkitt lymphoma in New Guinea: Establishment of a line of lymphoblasts in vitro and description of their fine structure. J. nat. Cancer Inst. 39, 933–945 (1967).

    PubMed  CAS  Google Scholar 

  • Rabson, A.S., O’Conor, G.T., Baron, S., Whang, J.J., Legallais, F.Y.: Morphologic, cytogenetic and virologic studies in vitro of a malignant lymphoma from an African child. Int. J. Cancer 1, 89–106 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Rinneberg, H.: Adenosintriphosphatase, 5-Nukleotidase und Glycerophosphatase im Schnitt und Ausstrich menschlicher Lymphknoten. Diss. med., Frankfurt 1961.

    Google Scholar 

  • Rivas, C., Oliva, H.: El diagnóstico óptico de reticulosarcoma, revisado y corregido por la microscopia electrónica. Bol. Fund. Jiminez Diaz 7, 71–80 (1975).

    Google Scholar 

  • Robinowitz, B.N., Noguchi, S., Roenigk, Jr., H.H.: Tumor cell characterization in mycosis fungoides. Cancer (Philad.) 57, 1747–1753 (1976).

    Article  Google Scholar 

  • Rodt, H., Thiel, E., Thierfelder, S., Huhn, D., Götze, D., Brehm, G.: Spezifisches Anti-T-Lymphocyten-Globulin (sATG) für die Diagnostik lymphoproliferativer Erkrankungen. Klin. Wschr. 54, 361–366 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Rosas-Uribe, A., Variakojis, D., Molnar, Z., Rappaport, H.: Mycosis fungoides: An ultrastructural study. Cancer (Philad.) 34, 634–645 (1974).

    Article  Google Scholar 

  • Rosenthal, A.S., Davie, J.M., Rosenstreich, D.L., Cehrs, K.U.: Antibody-mediated internalization of B lymphocyte surface membrane immunoglobulin. Exp. Cell Res. 81, 317–329 (1973).

    Article  PubMed  CAS  Google Scholar 

  • Rozenszajn, L.A., Gutman, A., Radnay, J., Ben David, E., Shoham, D.: A study of the nature of ‘hairy’ cells, with emphasis on enzymatic markers. Amer. J. clin. Path. 66, 432–441 (1976).

    CAS  Google Scholar 

  • Rubin, A.D., Douglas, S.D., Chessin, L.N., Glade, P.R., Dameshek, W.: Chronic reticulolymphocytic leukemia. Reclassification of ‘leukemic reticuloendotheliosis’ through functional characterization of the circulating mononuclear cells. Amer. J. Med. 47, 149–162 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Ryan, E.A., Sanderson, K.V., Barták, P., Samman, P.D.: Can mycosis fungoides begin in the epidermis? A hypothesis. Brit. J. Derm. 88, 419–429 (1973).

    Article  PubMed  CAS  Google Scholar 

  • Sandbank, M.: Mycosis fungoides. Ultrastructural study with demonstration of atypical cells and nuclear bodies. Arch. Derm. 103, 206–214 (1971).

    Article  PubMed  CAS  Google Scholar 

  • Sandbank, M., Ben-Bassat, M.: Mycosis fungoides and Sézary’s syndrome. Israel J. med. Sci. 7, 1262–1270 (1971).

    PubMed  CAS  Google Scholar 

  • Schaefer, H.-E.: Die Ultrastruktur maligner Lymphome. In: Maligne Lymphome und monoklonale Gammopathien. Hämatologie und Bluttransfusion, Bd. 18, pp. 49–61. Löffler, H., Ed. München: Lehmanns 1976.

    Google Scholar 

  • Schaefer, H.E., Krüger, G.R.F., Fischer, R.: Morphological classification of malignant lymphomas: Ultrastructural, cytochemical and immunological results. Acta neuropath. (Berl.) Suppl. 6, 21–29 (1975).

    Google Scholar 

  • Schmalzl, F., Huhn, D., Asamer, H., Braunsteiner, H.: Hairy cell leukemia (‘leukemic reticuloendotheliosis’), reticulosarcoma, and monocytic leukemia. Cytochemical and ultrastructural investigations. Acta haemat. (Basel) 53, 257–276 (1975).

    Article  Google Scholar 

  • Schnitzer, B., Hammack, W. J.: B-lymphocyte nature of hairy cells in hairy-cell leukaemia. [Letter to the Editor.] Lancet 1974, II, p. 649.

    Article  Google Scholar 

  • Schnitzer, B., Hammack, W.J.: The hairy cell. [Letter to the Editor.] Hum. Path. 6, 262–263 (1975).

    Article  PubMed  CAS  Google Scholar 

  • Schnitzer, B., Kass, L.: Hairy-cell leukemia. A clinicopathologic and ultrastructural study. Amer. J. clin. Path. 61, 176–187 (1974).

    CAS  Google Scholar 

  • Schrek, R.: Ultrastructure of blood lymphocytes from chronic lymphocytic and lymphosarcoma cell leukemia. J. nat. Cancer Inst. 48, 51–64 (1972).

    PubMed  CAS  Google Scholar 

  • Schrek, R., Donnelly, W.J.: “Hairy” cells in blood in lymphoreticular neoplastic disease and “flagellated” cells of normal lymph nodes. Blood 27, 199–211 (1966).

    PubMed  CAS  Google Scholar 

  • Schumacher, H.R., Maugel, T.K., Davis, K.D.: The lymphocyte of chronic lymphatic leukemia. I. Electron microscopy — onset. Cancer (Philad.) 26, 895–903 (1970).

    Article  CAS  Google Scholar 

  • Schumacher, H.R., Szekely, I.E., Park, S.A., Fisher, D.R.: Ultrastructural studies on the acute leukemic lymphoblast. Blut 27, 396–406 (1973).

    Article  Google Scholar 

  • Schwarze, E.-W., Radaszkiewicz, T., Pülhorn, G., Goos, M., Lennert, K.: Maligne und benigne Lymphome des Auges, der Lid- und Orbitalregion. Virchows Arch. A 370, 85–96 (1976).

    CAS  Google Scholar 

  • Shigematsu, T., Kozuru, M., Hattori, K.: The fine structure of human myeloma cells and macroglobulin-producing cells. Acta haemat. jap. 33, 37–50 (1970).

    PubMed  CAS  Google Scholar 

  • Smetana, K., Gyorkey, F., Gyorkey, P., Busch, H.: Comparative studies on the ultrastructure of nucleoli in human lymphosarcoma cells and leukemic lymphocytes. Cancer Res. 30, 1149–1155 (1970).

    PubMed  CAS  Google Scholar 

  • Smetana, K., Heřmansky, F., Janele, J., Busch, H.: A further note on the ultrastructure of leukemic lymphocytes. Folia haemat. (Lpz.) 89, 1–14 (1968).

    CAS  Google Scholar 

  • Smith, J.L., Cawley, J.C., Barker, C.R.: The response to plant mitogens of two subpopulations of lymphocytes in a case of chronic lymphocytic leukaemia. Clin. exp. Immunol. 14, 397–408 (1973).

    PubMed  CAS  Google Scholar 

  • Söderström, N., Norberg, B.: Observations regarding the specific post-capillary venules of lymph nodes in malignant lymphomas. Acta path. microbiol. scand. A 82, 71–79 (1974).

    Google Scholar 

  • Splinter, T.A.W., Helder, A.W., Lucas, C.J., Feltkamp-Vroom, T.M.: Tubuloreticular structures in human lymphoid cell lines. A cell biological study. Brit. J. exp. Path. 56, 124–132 (1975).

    PubMed  CAS  Google Scholar 

  • Stein, H., Kaiserling, E., Lennert, K.: Immunoglobulin-production and surface-bound immunoglobulins in chronic lymphocytic leukemia, lymphosarcoma, and so-called reticulum cell sarcoma. In: Modern Trends in Human Leukemia. Hämatologie und Bluttransfusion, Bd. 14, pp. 97–106. Neth, R., Gallo, R.C., Spiegelman, S., Stohlman, Jr., F., Eds. München: Lehmanns 1974.

    Google Scholar 

  • Stein, H., Kaiserling, E., Stein, G.: Surface markers on hairy cells. Boll. Ist. sieroter. milan. Suppl. 53, 305 (1974).

    Google Scholar 

  • Stempak, J.G., Ward, R.T.: An improved staining method for electron microscopy. J. Cell Biol. 22, 697–701 (1964).

    Article  PubMed  CAS  Google Scholar 

  • Stewart, S.E., Lovelace, E., Whang, J.J., Ngu, V.A.: Burkitt tumor: Tissue culture, cytogenetic and virus studies. J. nat. Cancer Inst. 34, 319–327 (1965).

    PubMed  CAS  Google Scholar 

  • Stockinger, L.: Elektronenoptische Darstellung einer Makroglobulinretention in Plasmazellen des menschlichen Knochenmarks. J. Cell Biol. 15, 131–136 (1962).

    Article  PubMed  CAS  Google Scholar 

  • Suchi, T., Sato, T., Kobayashi, H., Akatsuka, H., Akaza, T., Kurita, S., Hoshino, M.: Reticulum cell sarcoma. Some characteristics of reticulum-cell-sarcoma cells. [Jap.] Jap. J. Cancer Clin. 19, 419–425 (1973).

    Google Scholar 

  • Swartzendruber, D.C., Il Ma, B., Murphy, W.H.: Localization of C-type virus particles in lymphoid germinal centers of C58 mice. Proc. Soc. exp. Biol. (N.Y.) 126, 731–734 (1967).

    Google Scholar 

  • Szakal, A.K., Hanna, Jr., M.G.: The ultrastructure of antigen localization and virus-like particles in mouse spleen germinal centers. Exp. mol. Path. 8, 75–89 (1968).

    Article  CAS  Google Scholar 

  • Thiel, E., Rodt, H., Huhn, D., Thierfelder, S.: Decrease and altered distribution of human T antigen on chronic lymphatic leukemia cells of T type, suggesting a clonal origin. Blood 47, 723–736 (1976).

    PubMed  CAS  Google Scholar 

  • Toshima, S., Takagi, N., Minowada, J., Moore, G.E., Sandberg, A.A.: Electron microscopic and cytogenetic studies of cells derived from Burkitt’s lymphoma. Cancer Res. 27, 753–771 (1967).

    PubMed  CAS  Google Scholar 

  • Trubowitz, S., Masek, B., Frasca, J.M.: Leukemic reticuloendotheliosis. Blood 38, 288–298 (1971).

    PubMed  CAS  Google Scholar 

  • Uzman, B.G., Saito, H., Kasac, M.: Tubular arrays in the endoplasmic reticulum in human tumor cells. Lab. Invest. 24, 492–498 (1971).

    PubMed  CAS  Google Scholar 

  • Variakojis, D., Rosas-Uribe, A., Rappaport, H.: Mycosis fungoides: Pathologic findings in staging laparotomies. Cancer (Philad.) 33, 1589–1600 (1974).

    Article  CAS  Google Scholar 

  • Veldman, J.E.: Histophysiology and Electron Microscopy of the Immune Response. Thesis, Groningen 1970. Groningen: N.V. Boekdrukkerij Dijkstra Niemeyer 1970.

    Google Scholar 

  • Venable, J.H., Coggeshall, R.: A simplified lead citrate stain for use in electron microscopy. J. Cell Biol. 25, 407–408 (1965).

    Article  PubMed  CAS  Google Scholar 

  • Vykoupil, K.F., Thiele, J., Georgii, A.: Hairy cell leukemia. Bone marrow findings in 24 patients. Virchows Arch. A 370, 273–289 (1976).

    CAS  Google Scholar 

  • Ward, A.M., Shortland, J.R., Darke, C.S.: Lymphosarcoma of the lung with monoclonal (IgM) gammopathy. A clinicopathologic, histochemical, immunologic, and ultrastructural study. Cancer (Philad.) 27, 1009–1028 (1971).

    Article  CAS  Google Scholar 

  • Willighagen, R.G.J.: Histochemistry of enzymes in tumours. Ned. T. Geneesk. 105, 1356–1357 (1961).

    PubMed  CAS  Google Scholar 

  • Woessner, S., Rozman, C.: Ribosome-lamellae complex in chronic lymphatic leukaemia. Blut 33, 23–28 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Zucker-Franklin, D.: Virus-like particles in the lymphocytes of a patient with chronic lymphocytic leukemia. Blood 21, 509–512 (1963).

    PubMed  CAS  Google Scholar 

  • Zucker-Franklin, D.: Structural features of cells associated with the paraproteinemias. Semin. Hemat. 1, 165–198 (1964).

    PubMed  CAS  Google Scholar 

  • Zucker-Franklin, D.: Properties of the Sezary lymphoid cell. An ultrastructural analysis. Mayo Clin. Proc. 49, 567–574 (1974).

    PubMed  CAS  Google Scholar 

  • Zucker-Franklin, D., Melton III, J.W., Quagliata, F.: Ultrastructural, immunologic, and functional studies on Sézary cells: A neoplastic variant of thymus-derived (T) lymphocytes. Proc. nat. Acad. Sci. (Wash.) 71, 1877–1881 (1974).

    Article  CAS  Google Scholar 

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Kaiserling, E. (1978). Ultrastructure of Non-Hodgkin’s Lymphomas. In: Malignant Lymphomas Other than Hodgkin’s Disease. Handbuch der Speziellen Pathologischen Anatomie und Histologie, vol 1 / 3 / B. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81092-3_5

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