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Attempts to Understand Metastasis Formation III pp 155–166Cite as

Does Soluble CD44 Reflect the Clinical Behavior of Human Cancer?

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Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 213/3))

Abstract

Adhesion molecules are intimately involved in mediation of proper cell—cell contacts and communications in a wide variety of biological functions. During malignant trasformation, cells often lose precisely regulated contacts to the mircoenvironment. This may result in an increase of the amount of soluble adhesion molecules in blood circulation. In this review, we will present data on soluble forms of one adhesion molecule, CD44, and discuss the possibilities of using CD44 analyses in clinical practice.

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Authors and Affiliations

  1. National Public Health Institute, and MediCity Research Laboratory, Turku University, Tykistökatu 6, 20520, Turku, Finland

    R. Ristamäki & S. Jalkanen

  2. Department of Oncology and Radiotheraphy, Turku University, Kiinamyllynhatu 4-8, 20520, Turku, Finland

    R. Ristamäki

  3. Department of Oncology and Radiotheraphy, Helsinki University, Haartmaninkatu 4, 00290, Helsinki, Finland

    H. Joensuu

Authors
  1. R. Ristamäki
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  2. H. Joensuu
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  3. S. Jalkanen
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Editor information

Editors and Affiliations

  1. Basel Institute for Immunology, Grenzacherstraße 487, CH-4005, Basel, Switzerland

    Ursula Günthert Ph.D., P.D.

  2. Virchow Klinikum, Chirurgische Abteilung, Robert-Rössle-Klinik, Max-Delbrück-Centrum Berlin, Lindenberger Weg 80, D-13122, Berlin, Germany

    Peter M. Schlag M.D.

  3. Max-Delbrück-Centrum für Molekulare Medizin, Robert-Rössle-Straße 10, D-13122, Berlin, Germany

    Walter Birchmeier Ph.D.

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© 1996 Springer-Verlag Berlin Heidelberg

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Ristamäki, R., Joensuu, H., Jalkanen, S. (1996). Does Soluble CD44 Reflect the Clinical Behavior of Human Cancer?. In: Günthert, U., Schlag, P.M., Birchmeier, W. (eds) Attempts to Understand Metastasis Formation III. Current Topics in Microbiology and Immunology, vol 213/3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80071-9_10

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  • DOI: https://doi.org/10.1007/978-3-642-80071-9_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80073-3

  • Online ISBN: 978-3-642-80071-9

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