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The Electroencephalogram in Anesthesia pp 90–123Cite as

Intravenous Anesthetics

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Abstract

The intravenous induction of anesthesia has the great advantage of a rapid onset without any significant psychic distress to the patient. In 1847, the infusion of ether was used for the first time of intravenous anesthesia by Piro-goff. Worldwide acceptance of intravenous anesthesia was brought about by Weese and Scharpf in 1932, who developed the water-soluble barbituric acid derivatives [64]. A large number of substances have since been developed and introduced for intravenous use. They differ according to the degree of distress they induce in parenchymous organs and their ability to be regulated; they can be used selectively for anesthesia. A classification of the various intravenous drugs assists in providing a summary of the choices available and in indicating drug application. The chemical substances for i.v. use can be divided into two major groups according to their historical development — the barbituric acid derivatives (barbiturates) and the non barbituric acid anesthetics. The latter are a mixed group as they include some drugs that are chemically unrelated. Kugler (1981) suggested a classification of the intravenous hypnotics and anesthetics into five groups on the basis of their central nervous site of action. They are listed below.

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Authors and Affiliations

  1. Zentrum für Anästhesiologie der Medizinischen Hochschule Hannover, Abt. IV, Krankenhaus Oststadt, Podbielskistr. 380, D-3000, Hannover 51, Germany

    Professor Dr. Ina Pichlmayr & Privat-Dozent Dr. Ulrich Lips

  2. Zentrum Neurologische Medizin, Abt. II, Institut für Klinische Neurophysiologie und Experimentelle Neurologie, Konstanty-Gutschow-Str. 8, D-3000, Hannover 61, Germany

    Professor Dr. Helmut Künkel

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  1. Professor Dr. Ina Pichlmayr
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  2. Privat-Dozent Dr. Ulrich Lips
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  3. Professor Dr. Helmut Künkel
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Pichlmayr, I., Lips, U., Künkel, H. (1984). Intravenous Anesthetics. In: The Electroencephalogram in Anesthesia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-69562-9_8

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  • DOI: https://doi.org/10.1007/978-3-642-69562-9_8

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