Abstract
Inorganic plasma sulfate (SO4)derives mainly from the metabolic breakdown of sulfur-containing amino acids. Most of the ingested sulfur is excreted as SO4 by the kidneys, the remainder being incorporated into glycosaminoglycans and sulfatides or needed for the detoxification of various compounds. The plasma concentration of SO4 is regulated by the kidney, since it is freely filtered by the glomerulus (Goudsmit et al. 1939) and actively reabsorbed by the proximal tubule (Ullrich et al. 1980). The renal handling of SO4 in chronic renal failure has been studied in only a few clinical investigations (Hayman and Johnson 1932; Hanze 1966), and none of them deals with children. Investigations of SO4 metabolism in chronic renal failure seems to be of special interest in children because of the higher protein turnover during growth.
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References
Becker EL, Heinemann OH, Igareski K, Hodler JE, Gershberg H (1960) Renal mechanism for the exretion of inorganic sulfate in man. J Clin Invest 39: 1909–1913
Globus DL, Becker E, Thompson DD (1961) Renal tubular transport of inorganic sulfate. Am J Physiol 200: 1105–1110
Goudsmit A Jr, Power MH, Bollmann JL (1939) The excretion of sulfates by the dog. Am J Physiol 125: 506–520
Hänze S (1966) Serumsulfat und Sulfatclearance bei normaler und eingeschränkter Nierenfunktion. Klin Wochenschr 44: 1247–1251
Hayman JM Jr, Johnson SM (1932) The excretion of inorganic sulfates. J Clin Invest 11: 607–619
Liappis N (1977) Geschlechtspezifische Unterschiede der Ausscheidung von freiem anorganischem Sulfat im 24-h-Urin von gesunden Kindern. Klin Pediatr 189: 248–252
Lotspeich WD (1947) Renal tubular reabsorption of inorganic sulfate in the normal dog. Am J Physiol 151: 311–318
Michalk D, Manz F (1980) Determination of inorganic plasma sulfate by indirect atomic absorption spectrophotometry. Clin Chim Acta 107: 43–48
Mudge GH, Berndt WO, Valtin H (1973) Tubular transport of urea, phosphate, uric acid, sulfate and thiosulfate. In: Orloff J, Berliner R, Geiger SR (eds) Handbook of physiology, Sect 8, Williams & Williams, Baltimore, pp 587–652
Ullrich KJ, Rumrich G, Klöss S (1980) Active sulfate reabsorption in the proximal convolution of the rat kidney: specificity, Na+ and HCO3 dependence. Pfluegers Arch 383: 159–163
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© 1982 Springer-Verlag Berlin Heidelberg
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Michalk, D., Manz, F., Schärer, K. (1982). Studies of Sulfate in Children with Chronic Renal Failure. In: Bulla, M. (eds) Renal Insufficiency in Children. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-68144-8_13
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DOI: https://doi.org/10.1007/978-3-642-68144-8_13
Publisher Name: Springer, Berlin, Heidelberg
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