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Assessing Virtual Reality Environments as Cognitive Stimulation Method for Patients with MCI

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Technologies of Inclusive Well-Being

Part of the book series: Studies in Computational Intelligence ((SCI,volume 536))

Abstract

Advances in technology in the last decade have created a diverse field of applications for the care of persons with cognitive impairment. This chapter is an attempt to introduce a virtual reality computer-based intervention, which can used for cognitive stimulating and disease progression evaluation of a wide range of cognitive disorders ranging from mild cognitive impairment (MCI) to Alzheimer’s disease and various dementias. Virtual reality (VR) environments have already been successfully used in cognitive rehabilitation and show increased potential for use in neuropsychological evaluation allowing for greater ecological validity while being more engaging and user friendly. Nevertheless a holistic approach has been attempted, in order to view the research themes and applications that currently exist around the “intelligent systems” healthcare given to the cognitively impaired persons, and thus looking at research directions, systems, technological frameworks and perhaps trends.

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Notes

  1. 1.

    Microsoft Kinect—www.kinectforwindows.org/www.xbox.com/kinect.

References

  1. Virvou, M., Katsionis, G.: On the usability and likeability of virtual reality games for education: the case of VR-ENGAGE. Comput. Educ. 50, 154–178 (2008)

    Article  Google Scholar 

  2. Lewis, T.M., Aggarwal, R., Rajaretnam, N., Grantcharov, T.P., Darzi, A.: Training in surgical oncology: the role of virtual reality simulation. Surg. Oncol. 20, 134–139 (2011)

    Article  Google Scholar 

  3. Rizzo, A., Kim, G.J.: A SWOT analysis of the field of virtual reality rehabilitation and therapy. Presence 14(2), 119–146 (2005)

    Article  Google Scholar 

  4. Rizzo, A., Schultheis, M., Kerns, K.A., Mateer, C.: Analysis of assets for virtual reality applications in neuropsychology. Neuropsychol. Rehabil. 14(1/2), 207–239 (2004)

    Article  Google Scholar 

  5. Laczo, J., Vlcek, K., Vyhnalek, M., Vajnerova, O., Ort, M., Holmerova, I., Tolar, M., Andel, R., Bojar, M., Hort, J.: Spatial navigation testing discriminates two types of amnestic mild cognitive impairment. Behav. Brain Res. 202, 252–259 (2009)

    Article  Google Scholar 

  6. Petersen, R.C., Smith, G.E., Waring, S.C., Ivnik, R.J., Tangalos, E.G., Kokmen, E.: Mild cognitive impairment: clinical characterization and outcome. Arch. Neurol. 56(3), 303–308 (1999)

    Article  Google Scholar 

  7. Gauthier, S., Reisberg, B., Zaudig, M., Petersen, R.C., Ritchie, K., Broich, K., Belleville, S., et al.: Mild cognitive impairment. Lancet 367(9518), 1262–1270 (2006)

    Article  Google Scholar 

  8. Petersen, R.C.: Mild cognitive impairment as a diagnostic entity. J. Intern. Med. 256(3), 183–194 (2004)

    Article  Google Scholar 

  9. Winblad, B., Palmer, K., Kivipelto, M., Jelic, V., Fratiglioni, L., Wahlund, L.-O., Nordberg, A., et al.: Mild cognitive impairment–beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment. J. Intern. Med. 256(3), 240–246 (2004)

    Article  Google Scholar 

  10. Eschweiler, G.W., Leyhe, T., Klöppel, S., Hüll, M.: New developments in the diagnosis of dementia. Dtsch. Ärzteblatt Int. 107(39), 677–683 (2010)

    Google Scholar 

  11. Hanfelt, J.J., Wuu, J., Sollinger, A.B., Greenaway, M.C., Lah, J.J., Levey, A.I., Goldstein, F.C.: An exploration of subgroups of mild cognitive impairment based on cognitive, neuropsychiatric and functional features: analysis of data from the National Alzheimer’s Coordinating Center. Am. J. Geriatr. Psychiatry: Official J. Am. Assoc. Geriatr. Psychiatry 19(11), 940–950 (2011)

    Article  Google Scholar 

  12. Petersen, R.C., Roberts, R.O., Knopman, D.S., Boeve, B.F., Geda, Y.E., Ivnik, R.J., Smith, G.E., et al.: Mild cognitive impairment: ten years later. Arch. Neurol. 66(12), 1447–1455 (2009)

    Article  Google Scholar 

  13. Gold, D.A.: An examination of instrumental activities of daily living assessment in older adults and mild cognitive impairment. J. Clin. Exp. Neuropsychol. 37–41 (2012)

    Google Scholar 

  14. Perneczky, R., Pohl, C., Sorg, C., Hartmann, J., Komossa, K., Alexopoulos, P., Wagenpfeil, S., et al.: Complex activities of daily living in mild cognitive impairment: conceptual and diagnostic issues. Age Ageing 35(3), 240–245 (2006)

    Article  Google Scholar 

  15. Guerreiro, R., Wojtas, A., Bras, J., Carrasquillo, M., Rogaeva, E., Majounie, E., Cruchaga, C., et al. : TREM2 Variants in Alzheimer’s Disease. N. Engl. J. Med. (2012) (121114171407007)

    Google Scholar 

  16. Patel, B.B., Holland, N.W.: Mild cognitive impairment: hope for stability, plan for progression. Clevel. Clin. J. Med. 79(12), 857–864 (2012)

    Article  Google Scholar 

  17. Albert, M.S., DeKosky, S.T., Dickson, D., Dubois, B., Feldman, H.H., Fox, N.C., Gamst, A., et al.: The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer’s & Dement. J. Alzheimer’s Assoc. 7(3), 270–279 (2011)

    Article  Google Scholar 

  18. Wang, H.-M., Yang, C.-M., Kuo, W.-C., Huang, C.-C., Kuo, H.-C.: Use of a modified spatial-context memory test to detect amnestic mild cognitive impairment. PLoS ONE 8(2), e57030 (2013)

    Article  Google Scholar 

  19. Pai, M.C., Jacobs, W.J.: Int. J. Geriatr. Psychiatry 19, 250–255 (2004)

    Google Scholar 

  20. Cherrier, M.M., Mendez, M., Perryman, K.: Neuropsychiatry Neuropsychol. Behav. Neurol. 14, 159–168 (2001)

    Google Scholar 

  21. Kalova, E., Vlcek, K., Jarolimova, E., Bures, J.: Behav. Brain Res. 159, 175–186 (2005)

    Article  Google Scholar 

  22. Kessels, R.P., Feijen, J., Postma, A.: Dement. Geriatr. Cogn. Disord. 20, 184–191 (2005)

    Article  Google Scholar 

  23. Mapstone, M., Steffenella, T.M., Duffy, C.J.: A visuospatial variant of mild cognitive impairment: getting lost between aging and AD. Neurology 60(5), 802–808 (2003)

    Article  Google Scholar 

  24. Hort, J., Laczó, M., Vyhnálek, M., Bojar, J., Bureš, J., Vlček, K.: Spatial navigation deficit in amnestic mild cognitive impairment. Proc. Natl. Acad. Sci. 104(10), 4042–4047 (2007)

    Google Scholar 

  25. Rey, B., Alcañiz, M.: Research in Neuroscience and Virtual Reality. InTech (2010)

    Google Scholar 

  26. Cornwell, B.R., Johnson, L.L., Holroyd, T., Carver, F.W., Grillon, C.: Human hippocampal and parahippocampal theta during goal-directed spatial navigation predicts performance on a virtual Morris water maze. J. Neurosci.: Official J. Soc. Neurosci. 28(23), 5983–5990 (2008)

    Article  Google Scholar 

  27. Harvey, C.D., Collman, F., Dombeck, D.A., Tank, D.W.: Intracellular dynamics of hippocampal place cells during virtual navigation. Nature 461(7266), 941–946 (2009)

    Article  Google Scholar 

  28. Plancher, G., Tirard, A., Gyselinck, V., Nicolas, S., Piolino, P.: Using virtual reality to characterize episodic memory profiles in amnestic mild cognitive impairment and Alzheimer’s disease: influence of active and passive encoding. Neuropsychologia 50(5), 592–602 (2012)

    Article  Google Scholar 

  29. Slater, M., Antley, A., Davison, A., Swapp, D., Guger, C., Barker, C., Pistrang, N., et al.: A virtual reprise of the Stanley Milgram obedience experiments. PLoS ONE 1, e39 (2006)

    Article  Google Scholar 

  30. Waller, D., Richardson, A.R.: Correcting distance estimates by interacting with immersive virtual environments: effects of task and available sensory information. J. Exp. Psychol. Appl. 14(1), 61–72 (2008). doi:10.1037/1076-898X.14.1.61

    Article  Google Scholar 

  31. Klauer, K.C., Zhao, Z.: Double dissociations in visual and spatial short-term memory. J. Exp. Psychol. Gen. 133(3), 355–381 (2004)

    Article  Google Scholar 

  32. Lithfous, S., Dufour, A., Després, O.: Spatial navigation in normal aging and the prodromal stage of Alzheimer’s disease: insights from imaging and behavioral studies. Ageing Res. Rev. 12(1), 201–213 (2012)

    Article  Google Scholar 

  33. O’Keefe, J., Dostrovsky, J.: Brain Res. 34, 171–175 (1971)

    Google Scholar 

  34. Morris, R.G., Garrud, P., Rawlins, J.N., O’Keefe, J.: Nature 297, 681–683 (1982)

    Article  Google Scholar 

  35. Astur, R.S., Taylor, L.B., Mamelak, A.N., Philpott, L., Sutherland, R.J.: Behav. Brain Res. 132, 77–84 (2002)

    Article  Google Scholar 

  36. Feigenbaum, J.D., Morris, R.G.: Neuropsychology 18, 462–472 (2004)

    Article  Google Scholar 

  37. Maguire, E.A., Burgess, N., Donnett, J.G., Frackowiak, R.S., Frith, C.D., O’Keefe, J.: Science 280, 921–924 (1998)

    Article  Google Scholar 

  38. Abrahams, S., Pickering, A., Polkey, C.E., Morris, R.G.: Neuropsychologia 35, 11–24 (1997)

    Article  Google Scholar 

  39. De Lillo, C., James, F.C.: Spatial working memory for clustered and linear configurations of sites in a virtual reality foraging task. Cogn. Process. 13(Suppl 1), S243–S246 (2012)

    Article  Google Scholar 

  40. Koenig, S., Crucian, S., Dalrymple-Alford, J., Dünser, A.: Assessing navigation in real and virtual environments: a validation study. Int. J. Disabil. Hum. Dev. 10(4), 325–330 (2010)

    Google Scholar 

  41. Caffo, A., De Caro, M., Picucci, L., Notarnicola, A., Settanni, A., Livrea, P., Lancioni, G., Bosco, A.: Reorientation deficits are associated with amnestic mild cognitive impairment. Am. J. Alzheimer’s Dis. Dement. 27(5), SAGE Aug 1 (2012)

    Google Scholar 

  42. Liarokapis, F., Anderson, E.: Using augmented reality as a medium to assist teaching in higher education. To appear in Eurographics 2010, Education Program, Norrkfping, Sweden, 4–7 May 2010

    Google Scholar 

  43. Tsolaki, M., Kounti, F., Agogiatou, C., Poptsi, E., Bakoglidou, E., Zafeiropoulou, M., Soumbourou, A., et al.: Effectiveness of nonpharmacological approaches in patients with mild cognitive impairment. Neuro-degenerative Dis. 8(3), 138–145 (2011)

    Article  Google Scholar 

  44. Tsatali, M., Tarnanas, I., Malegiannaki, A., Tsolaki, M.: Does cognitive training with the use of a virtual museum improve neuropsychological performance in aMCI? In: 22nd Alzheimer Europe Conference in Vienna, Assistive Technologies P3, 121–134 (2012)

    Google Scholar 

  45. Ackerman, P.L., Kanfer, R., Calderwood, C.: Use it or lose it? WII brain exercise practice and reading for domain knowledge. Psychol. Aging 25, 753–766 (2010)

    Article  Google Scholar 

  46. Owen, A.M., Hampshire, A., Grahn, J.A., Stenton, R., Dajani, S., Burns, A.S., Howard, R.J., Ballard, C.G.: Putting brain training to the test. Nature 465, 775–778 (2010)

    Article  Google Scholar 

  47. Peretz, C., Korczyn, A.D., Shatil, E., Aharonson, V., Birnboim, S., Giladi, N.: Computer-based, personalized cognitive training versus classical computer games: a randomized double-blind prospective trial of cognitive stimulation. Neuroepidemiology 36, 91–99 (2011)

    Article  Google Scholar 

  48. Hertzog, C., Kramer, A.F., Wilson, R.S., Lindenberger, U.: Enrichment effects on adult cognitive development: can the functional capacity of older adults be preserved and enhanced? Psychol. Sci. Public Interest 9, 1–65 (2009)

    Google Scholar 

  49. Denney, N.W.: A model of cognitive-development across the life-span. Dev. Rev. 4, 171–191 (1984)

    Article  Google Scholar 

  50. Baron, A., Mattila, W.R.: Response slowing of older adults: effects of time-limit contingencies on single- and dual-task performances. Psychol. Aging 4, 66–72 (1989)

    Article  Google Scholar 

  51. Buschkuehl, M., Jaeggi, S.M., Hutchison, S., Perrig-Chiello, P., Dapp, C., Muller, M., Breil, F., Hoppeler, H., Perrig, W.J.: Impact of working memory training on memory performance in old–old adults. Psychol. Aging 23, 743–753 (2008)

    Article  Google Scholar 

  52. Dahlin, E., Neely, A.S., Larsson, A., Backman, L., Nyberg, L.: Transfer of learning after updating training mediated by the striatum. Science 320, 1510–1512 (2008)

    Article  Google Scholar 

  53. Sammer, G., Reuter, I., Hullmann, K., Kaps, M., Vaitl, D.: Training of executive functions in Parkinson’s disease. J. Neurol. Sci. 248, 115–119 (2006)

    Article  Google Scholar 

  54. Bherer, L., Kramer, A.F., Peterson, M.S., Colcombe, S., Erickson, K., Becic, E.: Transfer effects in task-set cost and dual-task cost after dual-task training in older and younger adults: further evidence for cognitive plasticity in attentional control in late adulthood. Exp. Aging Res. 34, 188–219 (2008)

    Article  Google Scholar 

  55. Davidson, D.J., Zacks, R.T., Williams, C.C.: Stroop interference, practice, and aging. Neuropsychol. Dev. Cogn. B AgingNeuropsychol. Cogn. 10, 85–98 (2003)

    Article  Google Scholar 

  56. Karbach, J., Kray, J.: How useful is executive control training? Age differences in near and far transfer of task-switching training. Dev. Sci. 12, 978–990 (2009)

    Article  Google Scholar 

  57. Ball, K., Berch, D.B., Helmers, K.F., Jobe, J.B., Leveck, M.D., Marsiske, M., Morris, J.N., Rebok, G.W., Smith, D.M., Tennstedt, S.L., Unverzagt, F.W., Willis, S.L.: Effects of cognitive training interventions with older adults: a randomized controlled trial. JAMA 288, 2271–2281 (2002)

    Article  Google Scholar 

  58. Schmiedek, F., Lovden, M., Lindenberger, U.: Hundred days of cognitive training enhance broad cognitive abilities in adulthood: findings from the COGITO study. Front. Aging Neurosci. 2, 27 (2010)

    Google Scholar 

  59. Klingberg, T.: Training and plasticity of working memory. Trends Cogn. Sci. 14, 317–324 (2010)

    Article  Google Scholar 

  60. Achtman, R.L., Green, C.S., Bavelier, D.: Video games as a tool to train visual skills. Restor. Neurol. Neurosci. 26, 435–446 (2008)

    Google Scholar 

  61. Green, C.S., Bavelier, D.: Exercising your brain: a review of human brain plasticity and training-induced learning. Psychol. Aging 23, 692–701 (2008)

    Article  Google Scholar 

  62. Gee, J.P.: What Video Games Have to Teach Us about Learning and Literacy. Palgrave Macmillan, New York, NY (2007)

    Google Scholar 

  63. Shiffrin, R.M., Schneider, W.: Controlled and automatic human information processing: II. Perceptual learning, automatic attending and a general theory. Psychol. Rev. 84, 127–190 (1977)

    Article  Google Scholar 

  64. Logan, G.D.: Automaticity, resources, and memory: theoretical controversies and practical implications. Hum. Factors 30, 583–598 (1988)

    Google Scholar 

  65. Feng, J., Spence, I., Pratt, J.: Playing an action video game reduces gender differences in spatial cognition. Psychol. Sci. 18, 850–855 (2007)

    Article  Google Scholar 

  66. Basak, C., Boot, W.R., Voss, M.W., Kramer, A.F.: Can training in a real-time strategy video game attenuate cognitive decline in older adults? Psychol. Aging 23(4), 756–777 (2008)

    Article  Google Scholar 

  67. Mahncke, H.W., Connor, B.B., Appelman, J., Ahsanuddin, O.N., Hardy, J.L., Wood, R.A., Joyce, N.M., Boniske, T., Atkins, S.M., Merzenich, M.M.: Memory enhancement in healthy older adults using a brain plasticity-based training program: a randomized, controlled study. Proc. Natl. Acad. Sci. U.S.A. 103, 12523–12528 (2006)

    Article  Google Scholar 

  68. Uchida, S., Kawashima, R.: Reading and solving arithmetic problems improves cognitive functions of normal aged people: a randomized controlled study. Age (Dordr.) 30, 21–29 (2008)

    Article  Google Scholar 

  69. Smith, G.E., Housen, P., Yaffe, K., Ruff, R., Kennison, R.F., Mahncke, H.W., Zelinski, E.M.: A cognitive training program based on principles of brain plasticity: results from the improvement in Memory with Plasticity-based Adaptive Cognitive Training (IMPACT) study. J. Am. Geriatr. Soc. 57, 594–603 (2009)

    Article  Google Scholar 

  70. Cicerone, K.D., Dahlberg, C., Kalmar, K., Langenbahn, D.M., Malec, J.F., Bergquist, T.F., Felicetti, T., Giacino, J.T., Harley, P.J., Harrington, D.E., Herzog, J., Kneipp, S., Laatsch, L., Morse, P.A.: Evidence-based cognitive rehabilitation: recommendations for clinical practice. Arch. Phys. Med. Rehabil. 81, 1596–1615 (2000)

    Article  Google Scholar 

  71. Cicerone, K.D., Dahlberg, C., Malec, J.F., Langenbahn, D.M., Felicetti, T., Kneipp, S., Ellmo, W., Kalmar, K., Giacino, J.T., Harlez, P., Laatsch, L., Morse, P., Catanese, J.: Evidence-based cognitive rehabilitation: updated review of the literature from 1998 through 2002. Arch. Phys. Med. Rehabil. 86, 1596–1615 (2005)

    Google Scholar 

  72. Tucker-Drob, E.M.: Neurocognitive functions and everyday functions change together in old age. Neuropsychology 25, 368–377 (2011)

    Article  Google Scholar 

  73. Ylvisaker, M., Turkstra, L.S., Coelho, C.: Behavioral and social interventions for individuals with traumatic brain injury: a summary of the research with clinical implications. Semin. Speech Lang. 26(4), 256–257 (2005)

    Article  Google Scholar 

  74. Sohlberg, M.M., Mateer, C.A. (eds.): Cognitive rehabilitation: an integrative neuropsychological approach. Guilford Press, New York (2001)

    Google Scholar 

  75. Mozolic, J.L., Hayasaka, S., Laurienti, P.J.: A cognitive training intervention increases resting cerebral blood flow in healthy older adults. Front. Hum. Neurosci. 4 (2010)

    Google Scholar 

  76. Lustig, C., Shah, P., Seidler, R., Reuter-Lorenz, P.A.: Aging, training, and the brain: a review and future directions. Neuropsychol. Rev. 19(4), 504–522 (2009)

    Google Scholar 

  77. Petersen, R.C., Parisi, J.E., Dickson, D.W., et al.: Neuropathologic features of amnestic mild cognitive impairment. Arch. Neurol. 63(5), 665–672 (2006)

    Article  Google Scholar 

  78. Stroop, J.R.: Studies of interference in serial verbal reactions. J. Exp. Psychol. 18, 643–662 (1935)

    Article  Google Scholar 

  79. Papaliagkas, V., Kimiskidis, V., Tsolaki, M., Anogianakis, G.: Usefulness of event-related potentials in the assessment of mild cognitive impairment. BMC Neurosci. 9, 107 (2008)

    Google Scholar 

  80. Kimiskidis, V., Papaliagkas, V.: Event-related potentials for the diagnosis of mild cognitive impairment and Alzheimer’s disease. Expert Opin. Med. Diagn. 6(1), 15–26 (2012)

    Google Scholar 

  81. Pascual-Marqui, D.: Standardized low-resolution brain electromagnetic tomography (sLORETA): technical details. Methods Find. Exp. Clin. Pharmacol. D 24, 5–12 (2002)

    Google Scholar 

  82. Holmes, A.P., Blair, R.C., Watson, J.D.G., Ford, I.: Nonparametric analysis of statistic images from functional mapping experiments. J. Cereb. Blood Flow Metab. 16(1), 7–22 (1996)

    Google Scholar 

  83. Li, S.C., Schmiedek, F., Huxhold, O., Röcke, C., Smith, J., Lindenberger, U.: Working memory plasticity in old age: practice gain, transfer, and maintenance. Psychol. Aging 23(4), 731–742 (2008)

    Google Scholar 

  84. Dennis, W., Scialfa, C.T., Ho, G.: Age differences in feature selection in triple conjunction search. J. Gerontol. B 59(4), P191–P198 (2004)

    Google Scholar 

  85. Ho, G., Scialfa, C.T.: Age, skill transfer, and conjunction search. J. Gerontol. B 57(3), P277–P287 (2002)

    Google Scholar 

  86. Cant, J.S., Goodale, M.A.: Attention to form or surface properties modulates different regions of human occipitotemporal cortex. Cereb. Cortex 17(3), 713–731 (2007)

    Google Scholar 

  87. Mechelh, A., Humphreys, G.W., Mayall, K., Olson, A., Price, C.J.: Differential effects of word length and visual contrast in the fusiform and lingual gyri during reading. Proc. Royal Soc. B 267(1455), 1909–1913 (2000)

    Google Scholar 

  88. Epstein., R.A.: Parahippocampal and retrosplenial contributions to human spatial navigation. Trends Cogn. Sci. 12(10), 88–396 (2008)

    Google Scholar 

  89. Falkenstein, M., Hohnsbein, J., Hoormann, J.: Effects of choice complexity on different subcomponents of the late positive complex of the event-related potential. Electroencephalogr. Clin. Neurophysiol. 92(2), 148–160 (1994a)

    Google Scholar 

  90. Falkenstein, M., Hohnsbein, J., Hoormann, J.: Time pressure effects on late components of the event-related potential (ERP). J. Psychophysiol. 8(1), 22–30 (1994b)

    Google Scholar 

  91. Tam, C.W., Lam, L.C., Chiu, H.F., Lui, V.W.: Characteristic profiles of instrumental activities of daily living in Chinese older persons with mild cognitive impairment. Am. J. Alzheimers Dis. Dement. 22, 211–217 (2007)

    Article  Google Scholar 

  92. Pereira, F.S., Yassuda, M.S., Oliveira, A.M., Forlenza, O.V.: Executive dysfunction correlates with impaired functional status in older adults with varying degrees of cognitive impairment. Int. Psychogeriatr. 20, 1104–1115 (2008)

    Article  Google Scholar 

  93. Ahn, I.S., et al.: Impairment of instrumental activities of daily living in patients with mild cognitive impairment. Psychiatry Inv. 6, 180–184 (2009)

    Article  Google Scholar 

  94. Burton, C.L., Strauss, E., Bunce, D., Hunter, M.A., Hultsch, D.F.: Functional abilities in older adults with mild cognitive impairment. Gerontology 55, 570–581 (2009)

    Article  Google Scholar 

  95. Schmitter-Edgecombe, M., Woo, E., Greeley, D.R.: Characterizing multiple memory deficits and their relation to everyday functioning in individuals with mild cognitive impairment. Neuropsychology 23, 168–177 (2009)

    Article  Google Scholar 

  96. Aretouli, E., Brandt, J.: Everyday functioning in mild cognitive impairment and its relationship with executive cognition. Int. J. Geriatr. Psychiatry 25, 224–233 (2010)

    Article  Google Scholar 

  97. Bangen, K.J., et al.: Complex activities of daily living vary by mild cognitive impairment subtype. J. Int. Neuropsychol. Soc. 16, 630–639 (2010)

    Article  Google Scholar 

  98. Teng, E., Becker, B.W., Woo, E., Cummings, J.L., Lu, P.H.: Subtle deficits in instrumental activities of daily living in subtypes of mild cognitive impairment. Dement. Geriatr. Cogn. Disord. 30, 189–197 (2010)

    Article  Google Scholar 

  99. Teng, E., Becker, B.W., Woo, E., Knopman, D.S., Cummings, J.L., Lu, P.H.: Utility of the functional activities questionnaire for distinguishing mild cognitive impairment from very mild Alzheimer disease. Alzheimer Dis. Assoc. Disord. 24, 348–353 (2010)

    Article  Google Scholar 

  100. Schmiedek, F., Bauer, C., Lovden, M., Brose, A., Lindenberger, U.: Cognitive enrichment in old age: web-based training programs. GeroPsych 23(2), 59–67 (2010)

    Google Scholar 

  101. Nouchi, R., Taki, Y., Takeuchi, H., Hashizume, H., Akitsuki, Y., Shigemune, Y., Sekiguchi, A., Kotozaki, Y., Tsukiura, T., Yomogida, Y., Kawashima, R.: Brain training game improves executive functions and processing speed in the elderly. PLoS ONE 7, e29676 (2012)

    Article  Google Scholar 

  102. Saczynski, J.S., Rebok, G.W., Whitfield, K.E., Plude, D.J.: Effectiveness of CD-ROM memory training as a function of within-session autonomy. Int. J. Cogn. Technol. 9(1), 25–33 (2004)

    Google Scholar 

  103. Lee, B., Chen, Y., Hewitt, L.: Age differences in constraints encountered by seniors in their use of computers and the internet. Comput. Hum. Behav. 27(3), 1231–1237 (2011)

    Article  Google Scholar 

  104. Torres, A.: Cognitive effects of video games on older people. ICDVRAT 19, 191–198 (2008)

    Google Scholar 

  105. Belchior, P.D.C. Cognitive training with video games to improve driving skills and driving safety among older adults [dissertation]. ProQuest Information and Learning (2008)

    Google Scholar 

  106. Colcombe, S., Kramer, A.F.: Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychol. Sci. 14, 125–130 (2003)

    Article  Google Scholar 

  107. Weiand, C.: Neuropsychologische Behandlungsmethoden im Vergleich—Eine randomisierte klinische Studie [Comparing neuropsychological treatment methods—A randomized clinical trial]. PhD dissertation, University of Konstanz, Konstanz (2006)

    Google Scholar 

  108. Colzato, L.S., Van Muijden, J., Band, G.P.H., Hommel, B.: Genetic modulation of training and transfer in older adults: BDNF Val66Met polymorphism is associated with wider useful field of view. Front. Psychol. 2, 199 (2011)

    Article  Google Scholar 

  109. Geusgens, C., Winkens, I., van Heugten, C., Jolles, J., van den Heuvel, W.: The occurence and measurement of transfer in cognitive rehabilitation: a critical review. J. Rehabil. Med. 39(6), 425–439 (2007)

    Google Scholar 

  110. Slater, M.: Place illusion and plausibility can lead to realistic behaviour in immersive virtual environments. Philos. Trans. R. Soc. B: Biol. Sci. 364, 3549–3557 (2009)

    Article  Google Scholar 

  111. Lange, B., Rizzo, A., Chang, C.-Y., Suma, E., Bolas, M.: Markerless Full Body Tracking: Depth-Sensing Technology within virtual environments. Paper presented at the Interservice/Industry Training, Simulation, and Education Conference (I/ITSEC), Orlando (2011)

    Google Scholar 

  112. Nebelrath, R., Lu, C., Schulz, C.H., Frey, J., Alexandersson, J.: A gesture based system for context-sensitive interaction with smart homes. In: Wichert, R., Eberhardt, B. (eds.), 4. AALKongress, pp. 209–222 (2011)

    Google Scholar 

  113. Hart, T.A., Chaparro, B.S., Halcomb, C.G.: Evaluating websites for older adults: adherence to ‘senior-friendly’ guidelines and end-user performance. Behav. Info. Technol. 27(3), 191–199 (2008)

    Article  Google Scholar 

  114. Pew Internet and American Life Project: Changes in internet use by age, 2000–2010. Accessed 24 Jul 2011 (2010)

    Google Scholar 

  115. Gamberini, L., Alcaniz, M., Barresi, G., Fabregat, M., Ibanez, F., et al.: Cognition, technology and games for the elderly: an introduction to ELDERGAMES project. PsychNology J 4(3), 285–308 (2006)

    Google Scholar 

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Authors and Affiliations

  1. School of Medicine, Aristotle University of Thessaloniki, 3rd Neurological Clinic, Papanikolaou Avenue, 570 10, Exohi, Thessaloniki, Greece

    Ioannis Tarnanas & Magda Tsolaki

  2. School of Electrical and Computer Engineering, Aristotle University of Thessaloniki, Egnatia Street, 54124, Thessaloniki, Greece

    Apostolos Tsolakis

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  1. Ioannis Tarnanas
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  2. Apostolos Tsolakis
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  3. Magda Tsolaki
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Correspondence to Ioannis Tarnanas .

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Editors and Affiliations

  1. Department of Architecture, Design and Media Technology, Aalborg University, Esbjerg, Denmark

    Anthony Lewis Brooks

  2. Computer Information Systems, Missouri State University, Springfield, Massachusetts, USA

    Sheryl Brahnam

  3. Faculty of Education, Science, Technology & Mathematics, University of Canberra, Canberra, Australia

    Lakhmi C. Jain

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Tarnanas, I., Tsolakis, A., Tsolaki, M. (2014). Assessing Virtual Reality Environments as Cognitive Stimulation Method for Patients with MCI. In: Brooks, A., Brahnam, S., Jain, L. (eds) Technologies of Inclusive Well-Being. Studies in Computational Intelligence, vol 536. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-45432-5_4

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  • DOI: https://doi.org/10.1007/978-3-642-45432-5_4

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